Journals / Retina-Vitreus / 2010 / Cilt: 18 - Sayı: 4

Case of severe sterile endophthalmitis after intravitreal bevacizumab

İntravitreal bevacizumab sonrası gelişen ağır bir steril endoftalmi olgusu

Pages
330–332
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Differentiation between sterile and infectious endophthalmitis is important as unnecessary treatment in the former case and the delay in treatment in the latter case.

📌 3 Key Takeaways

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Objective & Hypothesis:In this case report a severe sterile endophthalmitis after intravitreal bevacizumab injection for exudative age-related macular degeneration is presented.
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Key Findings & Data:He had conjunctival hyperemia and decreased visual acuity one week following 2nd dose of intravitreal injection of bevacizumab.
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Conclusion & Impact:Differentiation between sterile and infectious endophthalmitis is important as unnecessary treatment in the former case and the delay in treatment in the latter case.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this case report a severe sterile endophthalmitis after intravitreal bevacizumab injection for exudative age-related macular degeneration is presented. The patient had anterior uveitis with hypopyon, and severe vitritis that obscured fundus. He had conjunctival hyperemia and decreased visual acuity one week following 2nd dose of intravitreal injection of bevacizumab. The patient was presumed to have sterile intraocular inflammation since the vitreal cultures were negative, and the inflammation resolved with cycloplegic and topical corticosteroid therapy. Severe sterile endophthalmitis with hypopyon that mimics infectious endophthalmitis can occur after intravitreal bevacizumab. Differentiation between sterile and infectious endophthalmitis is important as unnecessary treatment in the former case and the delay in treatment in the latter case.

Özet

Bu çalışmada yaşa bağlı eksüdatif makula dejeneresansında intravitreal bevacizumab enjeksiyonu sonrası gelişen ağır bir steril endoftalmi olgusu sunulmuştur. Hastanın hipopiyonlu ön üveiti ve fundusun görülmesini engelleyen vitritisi mevcuttu. İntravitreal 2. doz bevacizumab enjeksiyonunu takiben bir hafta sonra konjonktival hipremi ve azalmış görme keskinliği bulunmaktaydı. Alınan vitreus kültürlerinin negatif olması ve topikal sikloplejik ve steroid tedavisi sonrası inflamasyonun gerilemesi nedeniyle hasta bir steril endoftalmi olgusu olarak değerlendirildi. Enfeksiyöz endoftalmiyi taklit edebilen hipopiyonlu ağır steril endoftalmi intravitreal bevacizumab enjeksiyonu sonrasında görülebilir. Steril ve enfeksiyöz endoftalmi ayrımının yapılması ilk durumun gereksiz tedavisini ve ikinci durumun da geç tedavisini engeller.

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Cite This Article

HAZIROLAN, D., ÜNLÜ, N., ACAR, M. A., ÜNEY, G. Ö., SUNGUR, G., DUMAN, S. (2010). Case of severe sterile endophthalmitis after intravitreal bevacizumab. Retina-Vitreus, Cilt: 18 - Sayı: 4, 330–332. https://ajindex.com/articles/307740

References (8)

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