SavedAdd your journal

Journals / Retina-Vitreus / 2012 / Cilt: 20 - Sayı: 2

Posterior mikroftalmi: 3 Vakanın klinik ve görüntüleme bulgularıyla değerlendirilmesi

Posterior microphthalmos: Assessment with clinical and imaging features of 3 cases

MEHMET YASİN TEKE
Alper YAZICI
MÜGE PINAR ÇAKAR ÖZDAL
YASEMİN ÖZDAMAR EROL
Faruk ÖZTÜRK
Pages
141–145
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Patients should be followed up properly for refractive amblyopia and for the complications that may emerge.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Posterior microphthalmos (PM) is a relatively rare type of microphthalmos in which the posterior segment is predominantly affected with normal anterior segment findings.
📊
Key Findings & Data:This paper consists of clinical and imaging findings of 3 PM cases.
💡
Conclusion & Impact:Patients should be followed up properly for refractive amblyopia and for the complications that may emerge.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Posterior microphthalmos (PM) is a relatively rare type of microphthalmos in which the posterior segment is predominantly affected with normal anterior segment findings. The main findings are high hypermetropia and elevated papillomacular folds. This paper consists of clinical and imaging findings of 3 PM cases. All cases had high hypermetropia (+17.00, +19.00, +17.00 dioptry) in cycloplegic refraction. The dilated fundus examination revealed elevated papillomacular folds in all the cases and crowded disk in only 2 of the 3 cases. In the B-scan ultrasound evaluation sclerochoroidal thickening, decreased total axial length (14.6-15.0 mm), and marked foreshortening of the posterior segment were noted. Fundus fluorescein angiography was performed in 2 patients and in those in which angiography was performed the foveal avascular zone seemed to be significantly reduced. Optic coherence tomography demonstrated the elevated papillomacular folds seen on dilated fundus examinations. The diagnosis of PM should be considered in patients with high axial hypermetropia, elevated papillomacular retinal folds, and normal anterior segment examination. Patients should be followed up properly for refractive amblyopia and for the complications that may emerge.

Özet

Posterior mikroftalmi (PM) normal ön segment bulgularıyla birlikte arka segmentin baskın olarak tutulduğu nadir bir mikroftalmi şeklidir. Temel bulguları yüksek hipermetropi ve yüzeyden kabarık papillomaküler retinal katlantılardır. Bu yazı 3 PM olgusunun klinik ve görüntüleme bulgularını içermektedir. Bütün olgularda sikloplejik refraksiyonda yüksek hipermetropi (+17.00, +19.00, +17.00 dioptri) mevcuttu. Dilate fundus muayenesinde tüm hastalarda yüzeyden kabarık papillomaküler katlantılar ve 3 hastanın 2 sinde kalabalık optik sinir başı görüldü. B-mod ultrason değerlendirmesinde sklerokoroidal kalınlaşma, azalmış total aksiyel uzunluk (14.6-15.0 mm) ve arka segmentin belirgin kısalığı izlendi. Fundus floresein anjiografi 2 olguda yapıldı, yapılan hastalarda foveal avasküler alanda ciddi daralma görüldü. Optik koherens tomografi dilate fundus muayenesinde izlenen yüzeyden kabarık papillomaküler foldları göstermiştir. PM tanısı aksiyel hipermetropi, yüzeyden kabarık papillomaküler retinal katlantılar ve normal ön segment muayenesi olan hastalarda düşünülmelidir. Hastalar refraktif ambliyopi ve gelişebilecek komplikasyonlar açısından doğru şekilde takip edilmelidir.

🔖

Cite This Article

TEKE, M. Y., YAZICI, A., ÖZDAL, M. P. Ç., EROL, Y. Ö., ÖZTÜRK, F. (2012). Posterior mikroftalmi: 3 Vakanın klinik ve görüntüleme bulgularıyla değerlendirilmesi. Retina-Vitreus, Cilt: 20 - Sayı: 2, 141–145. https://ajindex.com/articles/307693

References (14)

  1. Elder MJ. Aetiology of severe visual impairment and blindness in microphthalmos. Br J Ophthalmol 1994;78:332-4
  2. Khairallah M, Messaoud R, Zaouali S, et al. Posterior segment changes associated with posterior microphthalmos. Ophthalmology 2002;109:569-74
  3. Weiss AH, Kousseff BG, Ross EA, et al. Simple microphthalmos. Arch Ophthalmol 1989;107:1625-30
  4. Weiss AH, Kousseff BG, Ross EA, et al. Complex microphthalmos. Arch Ophthalmol 1989;107:1619-24
  5. Duke-Elder S. Anomalies in the size of the eye. In: Duke-Elder S editors. System of Ophthalmology. St Louis: C.V. Mosby 1963;3:488-95
  6. Brockhurst RJ. Nanophthalmos with uveal effusion (A new clinical entity). Trans Am Ophthalmol Soc 1974;72:371-403
  7. Spitznas M, Gerke E, Bateman VB. Hereditary posterior microphthalmos with papillomacular fold and high hyperopia. Arch Ophthalmol 1983;101:413-7
  8. Kida Y, Kurome H, Hayasaka S. Bilateral microphthalmos with poor visual acuity, high hyperopia, and papillomacular retinal folds in siblings. Jpn J Ophthalmol 1995;39:177-9
  9. Cennamo G, Magli A, Corvino C. Genetic and ultrasound study of hereditary pure microphthalmos. Ophthalmic Paediatr Genet 1985;6:277-82
  10. Boynton JR, Purnel EW. Bilateral microphthalmos without microcornea associated with unusual papillomacular folds and high hyperopia. Am J Ophthalmol 1975;79:820-6
  11. Hmani-Aifa M, Ben Salem S, Benzina Z, et al. A genomewide linkage scan in Tunisian families identifies a novel locus for non-syndromic posterior microphthalmia to chromosome 2q37.1. Hum Genet 2009;126:575-87
  12. Gal A, Rau I, El Matri L, et al. Autosomal-recessive posterior microphthalmos is caused by mutations in PRSS56, a gene encoding a trypsin-like serine protease. Am J Hum Genet 2011;11;88:382-90
  13. Ryckewaert M, Zanlonghi X, Bertrand-Cuignet H, et al. High hyperopia with papillomacular fold. Ophthalmologica 1992;204:49-53
  14. Crespı´ J, Buil JA. A novel mutation confirms MFRP as the gene causing the syndrome of nanophthalmos-retinitis pigmentosa- foveoschisis-optic disk drusen. Am J Ophthalmol 2008;146:323-8.