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Journals / Retina-Vitreus / 2015 / Cilt: 23 - Sayı: 1

Diyabetik Retinopatili Olgularda Panretinal Argon Lazer Fotokoagülasyon Sonrası Elektrofizyolojik Değişiklikler

Electrophysiologic Changes After Panretinal Argon Laser Photocoagulation in Patients with Diabetic Retinopathy

Ayşe ÖNER
Cengiz AKARSU
HATİCE ARDA
Koray GÜMÜŞ
Sarper KARAKÜÇÜK
Ertuğrul MİRZA
Pages
21–25
DOI
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⚡ TL;DR(Too Long; Didn't Read)

However we found a statistically significant reduction in the b wave amplitude of rod response, maximal combined response and cone response at the first month recordings after PRP.Conclusion: These findings indicated that both rods and cones could be damaged during the PRP treatment, however the damage might be more significant in the rod photoreceptors

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: The aim of this study is to evaluate the changes in functions of the retina and electrophysiologic tests after panretinal photocoagulation (PRP) in patients with diabetic retinopathy.
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Key Findings & Data:Material and Methods: 21 eyes of 21 diabetic patients with diabetic retinopathy who received laser treatment were included in the study.
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Conclusion & Impact:However we found a statistically significant reduction in the b wave amplitude of rod response, maximal combined response and cone response at the first month recordings after PRP.Conclusion: These findings indicated that both rods and cones could be damaged during the PRP treatment, however the damage might be more significant in the rod photoreceptors
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: The aim of this study is to evaluate the changes in functions of the retina and electrophysiologic tests after panretinal photocoagulation (PRP) in patients with diabetic retinopathy. Material and Methods: 21 eyes of 21 diabetic patients with diabetic retinopathy who received laser treatment were included in the study. At each visit a complete ophthalmic examination was performed including electrophysiologic tests (ERG, PERG, PVER and FVER).Results: When compared with pretreatment values there was not a statistically significant reduction in the amplitudes and latencies of P50 and N95 waves of PERG, P 100 waves of PVER at the first month recordings after PRP. However we found a statistically significant reduction in the b wave amplitude of rod response, maximal combined response and cone response at the first month recordings after PRP.Conclusion: These findings indicated that both rods and cones could be damaged during the PRP treatment, however the damage might be more significant in the rod photoreceptors

Özet

Amaç: Bu çalışmanın amacı diabetik retinopatili olgularda panretinal argon laser fotokoagülasyon (PRF) sonrası retina fonksiyonlarında ve elektrofizyolojik testlerde oluşan değişiklikleri değerlendirmektir. Gereç ve Yöntem: Lazer tedavisi alan 21 olgunun 21 gözü çalışmaya dahil edildi. Her kontrolde elektrofizyolojik testleri (ERG, PERG, PVER and FVER) de içeren tam oftalmolojik muayene yapıldı. Bulgular: Tedavi öncesi değerler ile PRF'den bir ay sonraki değerler karşılaştırıldığında PERG'in P50 ve N95 dalgasının, PVER'in P100 dalgasının amplitüd ve latansları arasında istatistiksel olarak anlamlı farklar yoktu. Bununla beraber birinci ayda yapılan kayıtlarda rod yanıtının, maksimal kombine yanıtın ve kon yanıtının b dalga amplitüdünde anlamlı olarak azalma saptandı. Sonuç: Bu bulgular PRF sırasında her iki tür fotoreseptörün de hasar görebileceğini ancak rodlardaki hasarın daha belirgin olabileceğini gösterir

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Cite This Article

ÖNER, A., AKARSU, C., ARDA, H., GÜMÜŞ, K., KARAKÜÇÜK, S., MİRZA, E. (2015). Diyabetik Retinopatili Olgularda Panretinal Argon Lazer Fotokoagülasyon Sonrası Elektrofizyolojik Değişiklikler. Retina-Vitreus, Cilt: 23 - Sayı: 1, 21–25. https://ajindex.com/articles/307668

References (7)

  1. Diabetes control and complications trial research group. The relationship of glycemic exposure (HbA1c) to the risk of development and progression of retinopathy in the diabetes control and complications trial. Diabetes 1995;44:968-83. Early worsening of diabetic retinopathy in the diabetes control and complications trial. Arch Ophthalmol 1998;116:874-86. Aiello ML. Perspectives on diabetic retinopathy. Am J Ophthalmol 2003;136:122-35. Early treatment diabetic retinopathy study research group. Techniques for scatter and local photocoagulation treatment of diabetic retinopathy. Early treatment diabetic retinopathy study Report No. 3. Int. Ophthalmol. Clin 1987;27:254-64. Diabetic retinopathy study research group. Photocoagulation treatment of proliferative diabetic retinopathy: Clinical application of diabetic retinopathy study (DRS) findings: DRS Report Number 8. Ophthalmology 1981;88:583-600. Gündüz MK. Oftalmik elektrofizyoloji. Ret-Vit 2011;19:1-5.
  2. Afrashi F, Köse S, Eğrilmez D, ve ark. The evaluation of insulin dependent diabetes mellitus patients by visual evoked potential and electroretinography testing. Turkiye Klinikleri J Ophthalmol 2001;10:153-7.
  3. Odom JV, Bach M, Barber C, et al. Vaegan (2004) Visual evoked potentials Standard. Doc Ophthalmol 2004;108:115-23. ISCEV standard for clinical pattern electroretinography-2007 update. Holder GE, Brigell ME, Hawlina M, et al. for the International Society for Clinical Electrophysiology of Vision. Doc Ophthalmol 2007; 114:111-6. ISCEV Standard for full-field clinical electroretinography (2008 update) Marmor MF, Fulton AB, Holder GE, et al. (for the International Society for Clinical Electrophysiology of Vision) Doc Ophthalmol 2009;118:69-77.
  4. Roider J, Michaud N, Flotte T, et al. Histology of retinal lesions after continuous irradiation and selective microcoagulation of the retinal pigment epithelium. Ophthalmologe 1993;90:274-8. Stefansson E. Ocular Oxygenation and the treatment of diabetic retinopathy. Survey of Ophthalmology 2006;51:364-80.
  5. Zweng HC, Little HL, Han DP. Complications of argon laser photocoagulation. Trans Am Acad Ophthalmol Otolaryngol 1974;78:195-204.
  6. Shimura M, Yasuda K, Nakazawa T, et al. Visual dysfunction after panretinal photocoagulation in patients with severe diabetic retinopathy and good vision. Am J Ophthalmol 2005;140:8-15.
  7. Ferris FL, Podgor MJ, Davis MD. Diabetic retinopathy study research group. Macular edema in diabetic retinopathy study patients diabetic retinopathy study re