Journals / Retina-Vitreus / 2019 / Cilt: 28 - Sayı: 2

Quantitative Features of The Foveal Avascular Zone and Macular Capillary Plexuses In Healthy Individuals: An Optical Coherence Tomography Angiography Study

Sağlıklı Bireylerde Foveal Avasküler Zonun ve Maküler Kapiller Pleksusların Niceliksel Özellikleri: Bir Optik Koherens Tomografi Anjiyografi Çalışması

Pages
131–136
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These normative data may be of value as a reference of comparison in future studies of eyes with various pathologies.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To quantify foveal avascular zone (FAZ) area, FAZ perimeter, acircularity index of FAZ (AI), foveal density (FD) and vessel density of macular capillary plexuses using optical coherence tomography angiography (OCTA) in healthy individuals.
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Key Findings & Data:Inclusion criteria were best corrected visual acuity of at least 20/20 and no pathological fi ndings in ophthalmic examination.
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Conclusion & Impact:These normative data may be of value as a reference of comparison in future studies of eyes with various pathologies.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To quantify foveal avascular zone (FAZ) area, FAZ perimeter, acircularity index of FAZ (AI), foveal density (FD) and vessel density of macular capillary plexuses using optical coherence tomography angiography (OCTA) in healthy individuals. Materials and Methods: Healthy individuals who visited our outpatient clinic for routine ophthalmic examination were evaluated. Inclusion criteria were best corrected visual acuity of at least 20/20 and no pathological fi ndings in ophthalmic examination. The subjects were screened via FAZ, Non-Flow and Density assesment tool of OCTA. FAZ parameters and vessel density values of both superfi cial (SCP) and deep capillary plexuses (DCP) were measured. Results: In this cross-sectional study 95 eyes of 50 healthy individuals (22 male, 28 female) were evaluated. The mean age was 40.85 ± 15.22 (18 - 68) years. The mean FAZ area in SCP and full retinal vasculature was 0.50 ± 0.13 (0.23 ± 0.76) and 0.28 ± 0.11 (0.07 - 0.51) mm2 respectively. FAZ perimeter, AI and FD were 2.00 ± 0.44 (0.98 - 2.75) mm, 1.09 ± 0.03 (1.05 - 1.23) and 55.83±4.01 (45.16-64.90)% respectively. The vessel density values of whole image in SCP and DCP were 51.48 ± 2.44 (43.10 - 55.90) and 53.23 ± 5.34 (40.80 - 65.00)% respectively. Conclusion: OCTA provides objective values about FAZ area, perimeter, AI of FAZ, FD and vessel density of macular capillary plexuses. FD is a clinical indicator of macular capillary perfusion. These normative data may be of value as a reference of comparison in future studies of eyes with various pathologies.

Özet

Amaç: Sağlıklı bireylerde foveal avasküler zon (FAZ) alanı, FAZ çevresi, asirkülerite indeksi (Aİ), foveal dansite (FD) ve makuler kapiller pleksusların damarsal dansitelerinin optik koherens tomografi anjiyografi (OKTA) kullanarak ölçülmesi. Gereç ve Yöntemler: Polikliniğimize rutin göz muayenesi için gelen hastalar incelendi. Çalışma kapsamına alınma kriterleri en iyi düzeltilmiş görme keskinliğinin en az 20/20 olması ve oftalmik muayenede herhangi bir patolojisi olmaması olarak belirlendi. Bireyler OKTA’nın FAZ, Non-Flow ve Density değerlendirme aracı ile görüntülendi. FAZ parametreleri ve yüzeyel (YKP) ve derin (DKP) kapiller pleksusların damarsal yoğunlukları ölçüldü. Bulgular: Bu kesitsel çalışmada 50 sağlıklı bireyin (22 erkek, 28 bayan) 95 gözü incelendi. Ortalama yaş 40.85 ± 15.22 (18 - 68) yıldı. YKP’de ve tüm retina vaskülarizasyonunda ortalama FAZ alanı sırasıyla 0.50 ± 0.13 (0.23 ± 0.76) ve 0.28 ± 0.11 (0.07 - 0.51) mm2 idi. FAZ çevresi, Aİ ve FD sırasıyla 2.00 ± 0.44 (0.98 - 2.75) mm, 1.09 ± 0.03 (1.05 - 1.23) ve % 55.83 ± 4.01 (45.16 - 64.90) idi. Tüm retina damarsal yoğunluk alanları YKP ve DKP’de sırasıyla % 51.48 ± 2.44 (43.10 - 55.90) ve 53.23 ± 5.34 (40.80 - 65.00) idi. Sonuç: OKTA FAZ alanı, çevresi, asirkülerite indeksi, foveal dansite ve makuler kapiller pleksusların damarsal yoğunlukları hakkında objektif veriler sağlamaktadır. Foveal dansite makuler kapiller perfüzyonun klinik bir göstergesidir. Bu normatif veriler çeşitli patolojili gözlerde gelecek çalışmalar için referans değer olabilirler.

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Cite This Article

GÖKER, Y. Ş., KIZILTOPRAK, H. (2019). Quantitative Features of The Foveal Avascular Zone and Macular Capillary Plexuses In Healthy Individuals: An Optical Coherence Tomography Angiography Study. Retina-Vitreus, Cilt: 28 - Sayı: 2, 131–136. https://ajindex.com/articles/307586

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