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Journals / Retina-Vitreus / 2019 / Cilt: 28 - Sayı: 1

Effect of Photodynamic Therapy on Choroidal Vascular Index in Central Serous Chorioretinopathy

Santral Seröz Koryoretinopatide Fotodinamik Tedavinin Koroidal Vasküler İndekse Etkisi

ZAFER CEBECİ
ŞERİFE BAYRAKTAR
EMRE ALTINKURT
Nur KIR
Pages
7–11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The choroidal vascular index may be a useful biomarker for follow-up response in CSC.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate the changes in choroidal vascular index (CVI) after low fl uence photodynamic theraphy (PDT) in central serous chori- oretinopathy (CSC).
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Key Findings & Data:Materials and Methods: Patients with a complaint of longer than 6 months with the diagnosis of CSC and who has done low fl uence PDT was reviewed retrospectively.
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Conclusion & Impact:The choroidal vascular index may be a useful biomarker for follow-up response in CSC.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate the changes in choroidal vascular index (CVI) after low fl uence photodynamic theraphy (PDT) in central serous chori- oretinopathy (CSC). Materials and Methods: Patients with a complaint of longer than 6 months with the diagnosis of CSC and who has done low fl uence PDT was reviewed retrospectively. Patients with enhanced depth imaging (EDI) - optical coherence tomography (OCT) images before and after treatment were included in the study. 1500 μm subfoveal area evaluated after segmentation. CVI was defi ned as ratio of lumen area (LA) to total choroidal area (TCA) according to EDI-OCT images. Results: Twenty-three eyes of 19 patients were included in the study. The mean age was 43.21 ± 7.4, and 10 (52.6%) of the patients were male. Choroidal vascular index was 65.4% before treatment, 64.82% at 1 week, 62.42% at 1 month, and 62.97% at 6 months after treatment. A signifi cant decrease in choroidal vascular indecency was detected at 1 month and 6 months after treatment compared with before treatment (p<0.05). The pre-treatment subfoveal choroidal thickness was 457.65 ± 108.15 μm; 443,30 ± 108,38 μm in the 1. week, 416,60 ± 89,71 μm in the 1. month and 411,47 ± 101,29 μm in the 6. month. All choroidal thickness measurements after treatment were signifi cantly lower than before treatment (p <0.05). Conclusion: There was a signifi cant decrease in choroidal vascular index after PDT in CSC. The choroidal vascular index may be a useful biomarker for follow-up response in CSC.

Özet

Amaç: Santral seröz koryoretinopatide (SSKR) düşük fl uens fotodinamik tedavi sonrası (FDT) koroidal vasküler indeks (KVİ) üzerindeki değişimlerini değerlendirmek. Gereç ve Yöntemler: Altı aydan uzun şikayetleri olan ve kronik SSKR tanısı konularak düşük fl uens FDT tedavisi uygulanan hastaların dos- yaları retrospektif olarak incelendi. Tedavi öncesi ve tedavi sonrası arttırılmış derinlikli görüntülemeli (EDI) - optik koherens tomografi (OKT) görüntüleri olanlar çalışmaya alındı. 1500 μm’lik subfoveal alan segmente edilerek incelendi. Koroidal vasküler indeks; EDI-OKT’de koroidal damarların lümen boşluğu alanının (LA) tüm koroidal alana (TKA) oranlaması olarak bulundu. Bulgular: On dokuz hastanın 23 gözü çalışmaya alındı. Ortalama yaş 43.21±7.4, bulundu ve hastaların 10’u (%52.6) erkekti. Koroidal vasküler indeks tedavi öncesi % 65.4 iken tedavi sonrası 1. haftada % 64.82, 1. ayda % 62.42, 6. ayda % 62.97 saptandı. Tedavi öncesi ile tedavi sonrası karşılaştırıldığında 1. ay ve 6. ayda koroidal vasküler indekste anlamlı azalma saptandı (p<0.05). Tedavi öncesi subfoveal koroid kalınlığı de- ğeri 457.65±108,15 μm iken; 1. haftada 443.30±108.38 μm , 1. ayda 416.60±89.71 μm ve 6. ayda 411.47±101.29 μm bulundu. Tedavi sonrası tüm koroid kalınlığı ölçümleri tedavi öncesine göre anlamlı azalmıştı (p<0.05). Sonuç: SSKR’de fotodinamik tedavi sonrası koroidal vasküler indekste anlamlı azalma saptanmıştır. Koroidal vasküler indeks SSKR’de teda- viye cevabı izlemede faydalı bir gösterge olabilir.

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Cite This Article

CEBECİ, Z., BAYRAKTAR, Ş., ALTINKURT, E., KIR, N. (2019). Effect of Photodynamic Therapy on Choroidal Vascular Index in Central Serous Chorioretinopathy. Retina-Vitreus, Cilt: 28 - Sayı: 1, 7–11. https://ajindex.com/articles/307581

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