Journals / Romatizma Dergisi / 1999 / Cilt: 14 - Sayı: 1

Serum levels of prolactin in women with rheumatoid arthritis

Romatoid artritli kadınlarda serum prolaktin düzeyleri

Pages
11–14
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A better understanding of the factor that regulates prolactin secretion and the modulation of the immune system may provide new clues to the pathogenesis of rheumatoid arthritis.

📌 3 Key Takeaways

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Objective & Hypothesis:Basal serum levels of prolactin in 20 female patients with rheumatoid arthritis (RA) was assessed and compared with that of age matched 20 healthy female controls.
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Key Findings & Data:No significant differences (p>0.05) were found for serum prolactin measured thought it was slightly higher in RA patients (16.02±8.92 ng/ml)compared with controls (10.96±5.83 ng/ml).
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Conclusion & Impact:A better understanding of the factor that regulates prolactin secretion and the modulation of the immune system may provide new clues to the pathogenesis of rheumatoid arthritis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Artrit · romatoid · Prolaktin

Abstract

Basal serum levels of prolactin in 20 female patients with rheumatoid arthritis (RA) was assessed and compared with that of age matched 20 healthy female controls. No significant differences (p>0.05) were found for serum prolactin measured thought it was slightly higher in RA patients (16.02±8.92 ng/ml)compared with controls (10.96±5.83 ng/ml). The levels of prolactin in patients with RA did not correlate to the indices of disease activity, defined by disease duration, ESR, Latex titre, morning stiffness, pain visual analogue scores and the Ritchie articular index. A better understanding of the factor that regulates prolactin secretion and the modulation of the immune system may provide new clues to the pathogenesis of rheumatoid arthritis.

Özet

Romatoid artritli 20 kadın hastanın bazal serum prolaktin düzeyleri ölçüldü ve bu hastalarla yaşları bakımından eşleştirilmiş 20 sağlıklı kontrolün değerleriyle karşılaştırıldı. Romatoid artritli grubun (16,02±8,92 ng/m) serum prolaktin değerleri, kontrol grubuna (1096±5,83 ng/ml) göre biraz daha yüksek bulundu. Fakat bu yükseklik istatistiksel olarak anlamlılık göstermemiştir (p>0,05). Romatoid artritli hastaların prolaktin düzeyleri; hastalık süresi, sedimentasyon hızı, Latex titrasyonu, sabah tutukluğu süresi, ağrı VAS skoru ve Ritchie eklem indeksi gibi hastalık aktivasyon göstergeleri ile korele bulunmadı. Prolaktin salınımını ve immün sistemi regüle eden faktörlerin daha iyi anlaşılmasıyla romatoid artrit patogenezinde yeni ipuçları sağlanabilir.

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Cite This Article

KOÇYİĞİT, H., ÖLMEZ, N., ATAY, A., HIZLI, N., MEMİŞ, A., HASIRCI, M. (1999). Serum levels of prolactin in women with rheumatoid arthritis. Romatizma Dergisi, Cilt: 14 - Sayı: 1, 11–14. https://ajindex.com/articles/306074