AI Summary & Key Takeaways
AI InsightNeither clinical nor radiological findings demonstrated an association with ESR and CRP levels.
📌 3 Key Takeaways
Abstract
This study was planned to investigate the association of erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels with clinical and radiological findings of osteoarthritis. Forty-nine consecutive female patients with osteoarthritis of the knee enrolled in the study. Pain assessment was done using a visual analogue scale. Walking distance without pain, any joint deformity, Heberden and/or Bouchard nodules and body mass index (BMI) were recorded. All patients filled the Western Ontario and McMaster Universities Osteoarthritis Index. Laboratory investigations, including hemoglobin, ESR and CRP, were performed. Anteroposterior and lateral radiograms of the knee and posteroanterior radiograms of the hand were obtained. Osteoarthritis of the knee was scored according to the method of Kellgren-Lawrence. Mean age of the patients was 58.6±8.4 years. The mean values of ESR, CRP and BMI were 15,2±10 mm/h, 0.43±0.58 mg/dl (range 0-2.98), 30.64±4.43 kg/m2, respectively. A positive correlation was found between BMI and Kellgren-Lawrence score. There was no association between ESR and CRP levels with clinical findings. Neither clinical nor radiological findings demonstrated an association with ESR and CRP levels.
Özet
Amaç: Bu çalışma osteoartritli hastalarda eritrosit sedimentasyon hızı (ESH) ve C-reaktif protein (CRP) düzeyleri ile klinik ve radyolojik bulgular arasındaki ilişkiyi araştırmak amacıyla planlandı. Çalışmaya diz osteoartriti olan 49 kadın hasta alındı. Vizüel analog skala ile ağrı değerlendirmesi, ağrısız yürüme mesafesi, eklem deformitesi, Heberden ve/veya Bouchard nodülleri ve vücut kitle indeksi (VKÝ) kaydedildi. Bütün hastalara Western Ontario and McMaster Üniversitesi Osteoartrit indeksini içeren form dolduruldu, hemoglobin, ESH ve CRP düzeylerini içeren laboratuvar testleri yapıldı. Ayrıca anteroposterior ve lateral diz grafileri ile posteroanterior el grafileri çekildi. Diz osteoartriti Kellgren-Lawrence metoduna göre evrelendi. Hastaların ortalama yaşı 58,6 ± 8,4 yýl, ESH, CRP ve VKÝ ortalama değerleri ise sırasıyla 15,2±10 mm/saat, 0.43 ± 0,58 mg/dl (range 0-2,98) ve 30,64 ± 4,43 kg/m² idi. Kellgren-Lawrence skoru ve vücut kitle indeksi arasında pozitif korelasyon saptandı. ESH ve CRP değerleri ile klinik ve radyolojik bulgular arasında ilişki saptanmadı.