Journals / Romatizma Dergisi / 2007 / Cilt: 22 - Sayı: 3

Lipid profile in female patients with rheumatoid arthritis

Romatoid artritli kadın hastalarda lipid profili

Pages
88–90
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: According to this study no significant difference was found in lipid levels between the RA patients and control group.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To investigate the lipid profile in patients with rheumatoid athritis Patients and Methods: The levels of total serum cholesterol, triglycerides, high density lipoprotein cholesterol (HDL-chol), low density lipoprotein cholesterol (LDL-chol), sedimentation, C reactive protein (CRP) and rheumatoid factor (RF) in 40 postmenopausal female patients diagnosed as Rheumatoid Arthritis according to ACR criteria were compared with 40 postmenopausal healthy women at the same age group.
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Key Findings & Data:Results: The mean age, menopausal status and body mass index were similar in both groups (p>0.05).
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Conclusion & Impact:Conclusion: According to this study no significant difference was found in lipid levels between the RA patients and control group.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Lipidler · Artrit · romatoid

Abstract

Objective: To investigate the lipid profile in patients with rheumatoid athritis Patients and Methods: The levels of total serum cholesterol, triglycerides, high density lipoprotein cholesterol (HDL-chol), low density lipoprotein cholesterol (LDL-chol), sedimentation, C reactive protein (CRP) and rheumatoid factor (RF) in 40 postmenopausal female patients diagnosed as Rheumatoid Arthritis according to ACR criteria were compared with 40 postmenopausal healthy women at the same age group. Results: The mean age, menopausal status and body mass index were similar in both groups (p>0.05). In RA group, the levels of erythrocyte sedimentation rate and CRP were significantly higher than the control group (p=0.005, p=0.041 respectively). Levels of total cholesterol, triglycerides, LDL-chol levels did not show a significant difference between the groups (p>0.05). Serum HDL-chol levels were higher in RA patients but this difference was not significant (p=0.059). Conclusion: According to this study no significant difference was found in lipid levels between the RA patients and control group.

Özet

Amaç: Romatoid artritli (RA) hastaların lipid profilini incelemek Hastalar ve Yöntem: American College of Rheumatology (ACR) kriterlerine göre RA tanısı almış, postmenapozal döneminde 40 kadın hasta ile benzer yaş grubunda 40 sağlıklı kadın hastanın serum total kolesterol, trigliserid, yüksek dansiteli lipooprotein kolesterol (HDL-kol), düşük dansiteli lipoprotein kolesterol (LDL-kol), sedimentasyon, serum reaktif protein (CRP), romatoid faktör (RF) düzeyleri karşılaştırıldı. Bulgular: RA ve kontrol grubu arasında ortalama yaş, menapoz durumu ve vücut kitle indeksi yönünden anlamlı bir fark yoktu (p>0.05). RA grubunda sedimentasyon ve CRP düzeyleri istatistiksel anlamlı olarak yüksek bulundu (sırasıyla p=0.005, p=0.041). Her iki grup arasında serum total kolesterol, trigliserid, LDL-kol düzeyleri arasında anlamlı bir fark bulunamadı (p>0.05). Serum HDL-kol düzeyleri RA‘lı hastalarda daha yüksek olmasına karşın bu fark istatistiksel olarak anlamlı değildi (p=0.059). Sonuç: Bu çalışmada RA hasta grubu ile kontrol grubu arasında lipid düzeyleri açısından anlamlı bir fark bulunamamıştır.

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Cite This Article

GÜNDÜZ, B., ERHAN, B., BORİÇİ, S. H., BARDAK, A. N., KILIÇ, Z., AKYÜREK, B. (2007). Lipid profile in female patients with rheumatoid arthritis. Romatizma Dergisi, Cilt: 22 - Sayı: 3, 88–90. https://ajindex.com/articles/305932

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References (15)

  1. Allebeck P, Ahlbom A, Allander E. Increased mortality among per- sons with rheumatoid arthritis. Scand J Rheumatol 1981; 10: 301-6
  2. Goodson N, Marks J, Lunt M, Symmons D. Cardiovascular admissions and mortality in an inception cohort of patients with rheumatoid arthritis with onset in the 1980s and 1990s. Ann Rheum Dis. 2005; 64:1595-601
  3. Dahlqvist SR, Jonsson SW, Dahlen G. Lipoprotein (a) lipids and lipoproteins in patients with rheumatoid arthiritis. Ann Rheum Dis. 1991; 50: 366 -8
  4. Robert WC. Factors linking cholesterol to atherosclerotic plaques. Am J Cardiol 1988; 10; 62; 495-9
  5. Blakburn WD, Chatham WW. Laboratory findings in rheumatoid arthritis. In: Koopman WJ (ed). Arthritis and Allied conditions. Philadelphia: William & Wilkins, 1997:1089-109
  6. Lorber M, Aviram M, Linn S, Scharf Y,Brook JG. Hipocholestero- laemia and abrnormal high density lipoprotein in rheumatoid arthritis. Br J Rheum 1985; 24: 250-5
  7. Lakatos J, Harsagyi A. Serum total, HDL, LDL-cholesterol and triglyceride levels in patients with rheumatoid arthritis. Clin Biochem 1988; 21: 93-6
  8. Bacon AP, Moots JR. Extra-articular rheumatoid arthritis. In: Koopman JW (ed). Arthritis and Allied Conditions. A Textbook of Rheumatology. Baltimore: Williams and Wilkins, 1997: 1071-88
  9. Sattar N, McCarey WD, Capell H, McInnes IB. Explaining how "High-Grade" systemic inflammation accelerates vascular risk in rheumatoid arthritis. Circulation 2003; 108: 2957-63
  10. Wallenberg- Jonsson S, Öhman ML, Rantapaa-Dahlqvist SR. Cardiovascular morbidity and mortality in patients with seropositive rheumatoid arthritis in Northern Sweden. J Rheumatol 1997; 24: 445-51
  11. Minaur NJ, Jacoby RK, Cosh JA, Taylor G. Rasker JJ. Outcome after 40 years with rheumatoid arthritis: a prospective study of function, disease activity and mortality. J Rheumatol 2004;69: 3-8
  12. Rincon DI, Williams K, Stern PM. High incidence ofcardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors. Arthritis Rheum 2001; 44: 2737-45
  13. Dursunoğlu D, Evrengül H, Polat B, Tanrıverdi H, Çobankara V, Kaftan A, et al. Lp (a) lipoprotein and lipids in patients with rheumatoid arthritis: serum levels and relationship to inflammation. Rheumatol Int 2005; 25: 241-5
  14. Magaro M, Altomonte L, Zoli A, Mirone L, Ruffini MP. Serum lipid pattern and-apolipoproteins (a1 and B100) in active rheumatoid arthritis. Z Rheumatologie 1991; 50: 168-70
  15. Vottery R, Saigal R, Singhal N