Journals / Romatizma Dergisi / 2008 / Cilt: 23 - Sayı: 4

Pregnancy and rheumatic diseases

Gebelik ve romatizmal hastalıklar

Pages
143–150
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Post-partum flare is common in all the rheumatic diseases.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Pregnancy is an issue that should be well discussed in all patients with rheumatic diseases in reproductive age groups.
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Key Findings & Data:Most rheumatic diseases that are well controlled prior to pregnancy do not deteriorate in pregnancy, providing that the patient continues with appropriate disease-modifying therapy.
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Conclusion & Impact:Post-partum flare is common in all the rheumatic diseases.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Antifosfolipid sendromu · Lupus eritematozus · sistemik

Abstract

Pregnancy is an issue that should be well discussed in all patients with rheumatic diseases in reproductive age groups. Pregnancies in women with rheumatic diseases require a multidisciplinary, carefully monitored, coordinated approach before, during and after pregnancy to ensure the best possible success for mother and baby. Infertility is rarely due to the disease but can be associated with cyclophosphamide therapy. Most rheumatic diseases that are well controlled prior to pregnancy do not deteriorate in pregnancy, providing that the patient continues with appropriate disease-modifying therapy. In contrast to systemic lupus erythematozus, antiphospholipid syndrome, vasculitis and systemic sclerosis there is little evidence for poor maternal or fetal outcomes in rheumatoid arthritis or other forms of inflammatory arthritis such as psoriasis and seronegative spondyloarthropathies. Some patients with inflammatory arthritis go in to remission during pregnancy. Patients with renal involvement may be at increased risk of disease flare. During pregnancy it is essential to monitor all aspects of disease activity such as renal involvement, as well as pregnancy complications such as intrauterine growth retardation, thrombo-embolic disease and preeclampsia, particularly in patients with systemic lupus erythematozus, antiphospholipid syndrome , vasculitis and systemic sclerosis. Post-partum flare is common in all the rheumatic diseases.

Özet

Gebelik, üreme çağında olan romatizmal hastalıklı tüm bayanlarda önemle tartışılması gereken bir meseledir. Romatolojik hastalığı olan kadınlarda gebelik dönemi, öncesi ve sonrasında bebek ve annede en iyi sonucu sağlamak için multidisipliner, koordineli ve dikkatli bir yaklaşım gerekmektedir. Romatizmal hastalıklara bağlı infertilite nadir olmakla beraber siklofosfamid tedavisinin bir sonucu olarak ortaya çıkabilir. Çoğu romatizmal hastalıkta gebelik öncesinde yapılan iyi kontrol, uygun modifiye edici tedaviye gebelikte devam etmek şartıyla gebelik esnasında da kötüleşmeyi engeller. Sistemik lupus eritematozus, antifosfolipid sendrom, vaskülitler ve sistemik skleroz'un aksine romatoid artrit ve inflamatuar artritlerin diğer formları olan psöriasis ve seronegatif spondiloartropatilerde maternal ve fetal etkilere dair kanıtlar daha azdır. İnflamatuar artritli bazı hastalar gebelik esnasında remisyona girerler. Renal tutulumu olan hastalarda hastalığın alevlenme riskinde artış olabilir. Gebelik esnasında sistemik lupus eritematozus, antifosfolipid sendrom, vaskülitler ve sistemik sklerozisli gebelerin intrauterin gelişme geriliği, tromboembolik hastalıklar ve preeklampsi komplikasyonları açısından takip edilmeleri gerekmektedir. Gebelik sonrası alevlenme tüm romatizmal hastalıklarda yaygındır.

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Cite This Article

TEREKECİ, H., TOP, C. (2008). Pregnancy and rheumatic diseases. Romatizma Dergisi, Cilt: 23 - Sayı: 4, 143–150. https://ajindex.com/articles/305909

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