Journals / Retina-Vitreus / 2002 / Cilt: 10 - Sayı: 3

Risk factors effecting visual acuity in insulin-dependent diabetic subjects with diabetic retinopathy

İnsüline bağımlı olan diyabetik retinopatili hastalarda görme keskinliği üzerine etkili risk faktörleri

Pages
264–272
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: It is important to determine the risk factors effecting the visual acuity in decreasing the incidence of severe visual loss in insulin-dependent diabetic subjects.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To determine the risk factors affecting visual acuity in insulin-dependent diabetic subjects with diabetic retinopathy.
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Key Findings & Data:Methods: 72 eyes of 36 insulin-dependent diabetic patients attending to our clinic due to diabetic retinopathy were retrospectively analyzed.
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Conclusion & Impact:Conclusion: It is important to determine the risk factors effecting the visual acuity in decreasing the incidence of severe visual loss in insulin-dependent diabetic subjects.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Görme keskinliği · Diabetik retinopati · Geriyedönük çalışma

Abstract

Purpose: To determine the risk factors affecting visual acuity in insulin-dependent diabetic subjects with diabetic retinopathy. Methods: 72 eyes of 36 insulin-dependent diabetic patients attending to our clinic due to diabetic retinopathy were retrospectively analyzed. Medical history and detailed ocular findings were collected from patients' cards and records in diabetes clinic. Age, gender, age at the onset of diabetes, duration of diabetes, hemoglobin A1c (HbA1c) level, and presence of hypertension (HT), cataract, neovascularisation of iris (NVI), clinically significant macular edema (CSME), cystoid macular edema (CME), intraocular hemorrhage (IOH), fractional retinal detachment (TRD), preretinal hemorrhage, diabetic retinopathy (DR) and neovascular glaucoma (NVG) were the factors, which were evaluated for their effects on visual acuity. The multivariate-adjusted association between these factors and severe visual loss was evaluated with logistic regression analysis. On the other hand, Chi-square and Anova tests were used to investigate the independent effects of these factors on visual acuity. Results: As analyzed by multiple logistic regression model, HbA1c level, and presence of cataract, CME and IOH were found to be associated with severe visual loss (p<0,05); whereas, the effects of age, gender, age at the onset of diabetes, duration of diabetes, HT, NVI, NVG, CSME, TRD, preretinal hemorrhage and DR on visual acuity were found to be statistically insignificant (p>0,05). On the other hand, when the factors were investigated independently, high HbA1c level and presence of NVI, CSME, CME, IOH and proliferative DR were the statistically significant factors for visual loss (p<0,05); whereas, age, gender, age at the onset of diabetes, duration of diabetes, HT, cataract, NVG, TRD and preretinal hemorrhage did not have a statistically significant effect on visual acuity (p>0,05). Conclusion: It is important to determine the risk factors effecting the visual acuity in decreasing the incidence of severe visual loss in insulin-dependent diabetic subjects.

Özet

Amaç: Insulin bağımlı diyabetik retinopatili hastalarda, görme keskinliği üzerinde etkili olan risk faktörlerini belirlemek Gereç ve Yöntem: Diyabetik retinopati nedeniyle kliniğimize başvuran 36 insulin bağımlı diyabetik hastanın 72 gözü retrospektif olarak incelendi. Hastaların dosyalarından ve diyabet polikliniğindeki kayıtlarından, tıbbi hikayeleri ve ayrıntılı oküler muayene bulguları elde edildi. Görme keskinliği üzerine etkileri araştırılan faktörler yaş, cinsiyet, diyabetin başlangıç yaşı, diyabet süresi, hipertansiyon (HT), glikolize hemoglobin (HbA1c) seviyesi, katarakt, iris neovaskülarizasyonu (İN), klinik anlamlı maküla ödemi (KAMÖ), kistoid maküla ödemi (KMÖ), intraoküler hemoraji (İOH), traksiyonel retina dekolmanı (TRD), preretinal hemoraji, diyabetik retinopati (DR) ve neovasküler glokom (NVG) idi. Ciddi görmekaybı ve bu faktörler arasındaki çok değişkenli ilişki lojistik regresyon analizi ile değerlendirildi. Öte yandan, faktörlerin birbirinden bağımsız olarak görme keskinliği üzerine etkilerinin incelenmesinde Ki-kare ve Anova testleri kullanıldı. Bulgular: Lojistik regresyon analizinde, istatistiksel olarak anlamlı ciddi görme kaybına yol açan faktörlerin HgA1c seviyesi, katarakt, KMÖ, ve İOH olduğu bulunurken (p 0,05). Faktörler birbirinden bağımsız incelendiğinde ise, yüksek HgA1c seviyesi, İN, KAMÖ, KMÖ, İOH ve proliferatif DR' li olgularda görme keskinliğinin istatistiksel olarak anlamlı düzeyde düşük olduğu görülürken (p 0,05). Sonuç: Tip l diyabetik hastalarda görme keskinliği üzerine etkili olan risk faktörlerinin belirlenmesi, ciddi görme kaybı sıklığının azaltılmasında önemlidir.

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Cite This Article

BAYRAK, Y., YANYALI, A., ÖZMEN, D., KARAAĞAÇ, H., NOHUTÇU, A. F. (2002). Risk factors effecting visual acuity in insulin-dependent diabetic subjects with diabetic retinopathy. Retina-Vitreus, Cilt: 10 - Sayı: 3, 264–272. https://ajindex.com/articles/305415

References (15)

  1. Silink M. (Editör): Tanımlama, Epidemiyoloji ve Sınıflama, Çocukluk ve Ergenlik Döneminde Tip I Diyabet Elkitabı, Ankara, MedicoGraphics Ajans ve Matbaacılık Hizmetleri 1997;1
  2. Garcia CA, Ruiz RS: Clinical Symposia, Ocular Complications of Diabetes. Volume 44, Number 1. New Jersey. CIBA-GEIGY Corporation 1992;2-4,32
  3. Klein R, Klein BE, Moss SE, Davis MD, DeMets DL: The Wisconsin Epidemiologie Study of Diabetic Retinopathy II Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years. Arch Ophthalmol 1984; 102:520-526
  4. Diabetic Retinopathy, Retina and Vitreus, Basic and Clinical Science Course 1999-2000, San Francisco; 70-71
  5. Klein R, Klein BE, Moss SE, Cruickshanks KJ: The Wisconsin Epidemiologie Study of Diabetic Retinopathy: XVII. The 14-year incidence and progression of diabetic retinopathy and associated risk factors in type I diabetes. Ophthalmology 1998;105:1799-800
  6. Jerneld B, Algvere P: Relationship of duration and onset of diabetes to prevalence of diabetic retinopathy. Am J Ophthalmol 1986;102:431-437
  7. Spencer R, McMeel JW, Franks EP: Visual outcome in moderate and severe proiiferative diabetic retinopathy. Arch Ophthalmol 1981;99:1551-4
  8. Rand LI, Prud'homme GJ, Ederer F, Canner PL: Factors influencing the development of visual loss in advanced diabetic retinopathy. Diabetic Retinopathy Study (DRS) Report No
  9. Invest Ophthalmol Vis Sei 1985;26:983-91
  10. Fong DS, Ferris FL, Davis MD, Chew EY: The Early Treatment Diabetic Retinopathy Study Research Group: Causes of severe visual loss in the early treatment diabetic retinopathy study: ETDRS Report No.24. Am J Ophthalmol 1999;127:137-141
  11. The Diabetic Retinopathy Study Research Group: Four risk factors for severe visual loss in diabetic retinopathy. The third report from the diabetic retinopathy study. Arch Ophthalmol 1979;97:654-655
  12. Palmberg P, Smith M, Waltman S, et al: The natural history of retinopathy in insulin-dependent juvenile-onset diabetes. Ophthalmology 1981;88:613-618
  13. Frank RN, Hoffman WH, Podger MJ, et al: Retinopathy in juvenile-onset type I diabetes of short duration. Diabetes 1982;31:874-ê82
  14. Jackson RL, Ide CH, Guthrie RA, et al: Retinopathy in adolescents and young adults with onset of insulin-dependent diabetes in childhood. Ophthalmology 1982;89:7-13
  15. Klein R, Klein BE, Moss SE, Cruickshanks KJ: The Wisconsin. Epidemiologie Study of Diabetic Retinopathy. XIV. Ten-year incidence and progression of diabe