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Journals / Retina-Vitreus / 2006 / Cilt: 14 - Sayı: 3

Value of haemodynamic changes in the orbital arteries in the early recognition of ocular involvement of Behçet’s disease

Behçet hastalığının göz tutulumunun erken saptanmasında orbital arterlerdeki hemodinamik değişikliklerin değeri

Murat SÖNMEZ
Dilaver ERŞANLI
Zekai PEKKAFALI
Pages
175–180
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Particularly, end-diastolic velocity and pulsatility index are useful parameters in the recognition of ocular Behçet’s disease.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To investigate the changes in haemodynamic parameters in the orbital arteries by Color Doppler Ultrasonography (CDU) and to determine useful parameter(s) in the early recognition of ocular Behçet’s disease Materials and Methods: Study group included 104 eyes[30 eyes with ocular involvement (ocular Behçet’s-OB), 34 eyes without ocular involvement (non-ocular Behçet’s- NOB) and 40 normal eyes in control group (CG)].
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Key Findings & Data:T test with Bonferroni’s adjustment was used in statistical analysis.
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Conclusion & Impact:Particularly, end-diastolic velocity and pulsatility index are useful parameters in the recognition of ocular Behçet’s disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Oftalmik arter · Ultrasonografi · doppler

Abstract

Purpose: To investigate the changes in haemodynamic parameters in the orbital arteries by Color Doppler Ultrasonography (CDU) and to determine useful parameter(s) in the early recognition of ocular Behçet&#8217;s disease Materials and Methods: Study group included 104 eyes[30 eyes with ocular involvement (ocular Behçet&#8217;s-OB), 34 eyes without ocular involvement (non-ocular Behçet&#8217;s- NOB) and 40 normal eyes in control group (CG)]. Ocular blood flow velocities (OBFV) were obtained from ophthalmic artery (OA), central retinal artery (CRA) and posterior ciliary artery (PCA) by CDU, pulsatility index (PI) and resistivity index (RI) were calculated. T test with Bonferroni&#8217;s adjustment was used in statistical analysis. Results: OBFV&#8217;s significantly decreased in ocular compared to NOB and CG (p<0.0001). They were almost equal to or slightly different in NOB from CG for CRA. PI&#8217;s of OA and PCA in OB and NOB groups were higher than CG, and more evident in OB group (p< 0.03). In OB group, RI&#8217;s were higher than CG for all arteries, however higher only in OA when comparing with NOB(p<0.0001). Conclusion: There are significant reductions in the OBFV&#8217;s in the cases with Behçet&#8217;s disease and they are more evident in case of ocular involvement. Particularly, end-diastolic velocity and pulsatility index are useful parameters in the recognition of ocular Behçet&#8217;s disease.

Özet

Amaç: Behçet hastalığında Renkli Doppler Ultrasonografi (RDUS) ile orbital arterlerin hemodinamik parametrelerindeki değişikliklerin araştırılması ve Behçet hastalığının göz tutulumunun erken tanısında kullanışlı parametrelerin saptanmasıdır. Gereç ve Yöntem: Çalışma grubu 104 gözü kapsadı [30 göz tutulumlu(oküler Behçet- OB), 34 göz tutulumsuz (non-oküler Behçet- NOB) ve 40 normal (göz kontrol grubu- KG)] .Oftalmik arter (OA), santral retinal arter (SRA) ve arka silier arterden (ASA) RDUS ile oküler kan akım hızları (OKAH) parametreleri (MSH=maksimum sistolik hız, DSH=diastol sonu hız, OH=ortalama hız) elde edildi; pulzatilite indeksi (Pİ), rezistivite indeksi (Rİ) hesaplandı. İstatistiksel analizde Bonferroni düzeltmeli t testi kullanıldı. Bulgular: Oküler kan akım hızı oküler Behçet grubunda non-oküler Behçet grubuna ve kontrol grubuna göre anlamlı olarak azdı (p< 0.0001). SRA oküler kan akım hızı değeri non-oküler Behçet grubunda kontrol grubuna göre eşit veya hafifçe farklıydı. Oküler Behçet grubunda daha belirgin olmak üzere OA ve ASA’in pulzatilite indeks değeri non-oküler Behçet ve oküler Behçet grubunda kontrol grubuna göre yüksekti (p< 0.03). Oküler Behçet grubunda tüm arterlerde rezistivite indeks değeri kontrol grubundan anlamlı yüksek, non-oküler Behçet grubuna kıyasla ise sadece OA’de yüksekti (p< 0.0001). Sonuç: Behçet hastalığında OKAH değerinde belirgin azalma vardır ve göz tutulumu olan olgularda daha belirgindir. Özellikle diastol sonu hızı (DSH) ve pulzatilite indeksi (Pİ) Behçet hastalığının göz tutulumunun erken tanısında kullanışlı parametreler olabilir.

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Cite This Article

SÖNMEZ, M., ERŞANLI, D., PEKKAFALI, Z. (2006). Value of haemodynamic changes in the orbital arteries in the early recognition of ocular involvement of Behçet’s disease. Retina-Vitreus, Cilt: 14 - Sayı: 3, 175–180. https://ajindex.com/articles/305344

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