Journals / Retina-Vitreus / 2007 / Cilt: 15 - Sayı: 2

The role of hemorheologic factors in age related macular degeneration

Yaşa bağlı maküla dejenerasyonunda hemoreolojik faktörlerin rolü

Pages
129–131
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This can play a role in the development of AMD.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To investigate the role of plasma fibrinogen, hemoglobin, hematocrit, lipid and platelet levels in age related macular degeneration (AMD).
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Key Findings & Data:Materials and Methods: 30 patients with AMD and 29 healthy subjects as a control group were included in the study.
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Conclusion & Impact:This can play a role in the development of AMD.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To investigate the role of plasma fibrinogen, hemoglobin, hematocrit, lipid and platelet levels in age related macular degeneration (AMD). Materials and Methods: 30 patients with AMD and 29 healthy subjects as a control group were included in the study. Serum fibrinogen, hemoglobin, hematocrit, lipid and platelet counts were determined in two groups. Results: Serum fibrinogen level was 364.7±70.7 mg/dl in AMD group and 319.6±54.2 mg/dl in the control group. Fibrinogen levels were significantly higher in AMD group compared with control group (p<0.05). There was no statistically significant difference between two groups for the other parameters (p>0.05). Conclusion: Serum fibrinogen level is higher in patients with AMD. This can play a role in the development of AMD.

Özet

Amaç: Yaşa bağlı maküla dejenerasyonunda (YBMD) plazma fibrinojen, hemoglobin, hematokrit ve lipit düzeyleri ile trombosit sayısının etkisinin olup olmadığının araştırılması. Gereç ve Yöntem: Çalışmamıza 30 YBMD’si olan hasta ile kontrol grubu olarak 29 sağlıklı birey dahil edildi. Her iki grupta plazma fibrinojen düzeyi, hemoglobin, hematokrit ve lipit düzeyleri ile trombosit sayıları değerlendirildi. Bulgular: YBMD grubunda ortalama plazma fibrinojen düzeyi 364.7±70.7 mg/dl iken, kontrol grubunda 319.6±54.2 mg/dl idi. Fibrinojen düzeyleri kontrol grubu ile karşılaştırıldığında, YBMD grubunda anlamlı olarak daha yüksekti (p 0.05). Sonuç: Serum fibrinojeni, YBMD olan hastalarda daha yüksek olup, bu durum hastalığın oluşmasında rol oynayan faktörlerden biri olabilir

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Cite This Article

YAĞCI, R., OFLU, Y., ERDURMUŞ, M., DEMİR, N., ÜNLÜ, N., DURMUŞ, M., DUMAN, S. (2007). The role of hemorheologic factors in age related macular degeneration. Retina-Vitreus, Cilt: 15 - Sayı: 2, 129–131. https://ajindex.com/articles/305252

References (15)

  1. Weih L, Van Newkirk MR, McCarty CA,et al.: Age-specific causes of bilateral visual impairment. Arch Ophthalmol. 2000;11 8:264-269
  2. Vingerling J, Klaver CCW, Hofman A, et al.: Epidemiology of age-related maculopathy. Epidemiol Rev. 1995;17:347-360
  3. Lip PL, Blann AD, Hope-Ross M, et al.: Age-related macular degeneration is associated with increased vascular endothelial growth factor, hemorheology and endothelial dysfunction. Ophthalmology. 2001;108:705-710 4. Bird AC.: Age related macular disease. Br J Ophthalmol. 1996;80:1-2
  4. Hyman LG, Lilienfeld AM, Ferris FL 3rd, et al.: Senile macular degeneration: a case-control study. Am J Epidemiol. 1 983;1 1 8:213-227
  5. Goldberg J, Flowerdew G, Smith E, et al.: Factors associated with age-related macular degeneration. An analysis of data from the first National Health and Nutrition Examination Survey. Am J Epidemiol. 1988;128:700-710
  6. Vingerling JR, Dielemans I, Bots ML, et al.: Age-related macular degeneration is associated with atherosclerosis. The Rotterdam Study. Am J Epidemiol. 1995;142:404-409
  7. Sperduto RD, Hiller R. Systemic hypertension and age-related maculopathy in the Framingham Study. Arch Ophthalmol. 1986;104:216-219
  8. Kamış U, Okudan S, Özkağnıcı A.: Yaşa bağlı makula dejenerasyonunun oküler ve sistemik faktörler ile ilişkisi. T Oft Gaz. 2003;33:673-681
  9. The Eye Disease Case-Control Study Group: Risk factors for ne-ovascular age-related macular degeneration. Arch Ophthalmol. 1992;110:1701-1708
  10. Klein R, Klein BE, Franke T.: The relationship of cardiovascular disease and its risk factors to age-related maculopathy. The Beaver Dam Eye Study. Ophthalmology. 1993;100:406-414
  11. Vinding T, Appleyard M, Nyboe J,et al.: Risk factor analysis for atrophic and exudative age-related macular degeneration. An epidemiological study of 1000 aged individuals. Acta Ophthalmol. 1992;70:66-72
  12. Erakgün T, Nalçacı S, Menteş J, ve ark.: Eksüdatif tip yaşa bağlı makula dejeneresansında antioksidan indeks ve aterosklerotik risk faktör tayini. T Oft Gaz. 2003;33:278-284
  13. Blumenkranz MS, Russell SR, Robey MG, et al.: Risk factors in age-related maculopathy complicated by choroidal neovascularization. Ophthalmology. 1986;93:552-558 15. Klein BE, Klein R.: Cataracts and macular degeneration in older Americans. Arch Ophthalmol. 1982;100:571-573
  14. Lip GYH.: Fibrinogen and cardiovascular disease. Q Med. 1995;88:155-165
  15. Lowe GDO.: Blood rheology in arterial disease. Clin Sci. 1986;71:13