Journals / Retina-Vitreus / 2009 / Cilt: 17 - Sayı: 1

Optic coherence tomography and autofluorescence findings in chronic central serous chorioretinopathy

Kronik santral seröz koriyoretinopatide optik koherens tomografi ve otofloresans bulguları

Pages
9–13
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These granules can be visualize by OCT and AF imaging noninvasively.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: The purpose of the current study is to present optic coherence tomography (OCT) and autofluorescence (AF) finding of patients with chronic central serous chorioretinopathy (CSC).
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Key Findings & Data:Materials and Methods: Fifteen eyes of 15 patients diagnosed as chronic CSC in our retina department within the last two years was investigated retrospectively.
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Conclusion & Impact:These granules can be visualize by OCT and AF imaging noninvasively.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Tomografi · optik koherens · Melaninler

Abstract

Purpose: The purpose of the current study is to present optic coherence tomography (OCT) and autofluorescence (AF) finding of patients with chronic central serous chorioretinopathy (CSC). Materials and Methods: Fifteen eyes of 15 patients diagnosed as chronic CSC in our retina department within the last two years was investigated retrospectively. All patients underwent complete ophthalmic examination, fluorescein angiography, AF image (blue and infrared light), OCT imaging. A scanning laser ophthalmoscope (HRA2, Heidelberg Retina Angiograph 2) was used for FA and AF imaging. Nidek brand third generation spectral domain OCT was used for OCT imaging. Results: OCT imaging revealed subretinal granular aggregation especially in patients with prolonged serous detachment. These aggregates were observed as hyperautofluorescent mottling in AF imaging. Retinal pigment epithelial irregularities observed with OCT sections corresponding to leaking site were seen as hypoautofluorescecnt in AF imaging. Conclusion: In normal retinal physiology, photoreceptors continuously spread out their discoid outer segments into the subretinal space and they phagocytosed by the RPE. In the case of CSC with neurosensory retinal detachment the cycle disrupts. However photoreceptor outer segments continue to elongate and spreading towards the subretinal fluid and appear subretinal granular deposits. These granules can be visualize by OCT and AF imaging noninvasively.

Özet

Amaç: Bu çalışmada kronik santral seröz koriyoretinopatide (SSKR) optik koherens tomografi (OKT) ve otoflöresans bulgularının sunulması amaçlanmıştır. Gereç ve Yöntem: Kliniğimizde son iki yıl içerisinde kronik SSKR tanısı alan 15 olgunun 15 gözü retrospektif olarak çalışma kapsamında değerlendirildi. Tüm olguların tam oftalmolojik muayene bulguları, flöresein anjiyografi ve otoflöresans (mavi ışık ve kızılötesi) görüntüleri kayıt edildi. Bunun için bir konfokal tarayıcı lazer oftalmoskop olan Heidelberg Retina Angiograph 2 cihazı kullanıldı. OKT görüntülemede Nidek marka üçüncü kuşak spektral domain optik koherens tomografi cihazı kullanıldı. Bulgular: OKT incelemde seröz dekolmanın sebat ettiği olgularda hiperintens birikimler izlendi. Bu birikimlerin otoflöresans görüntülemede hiperotoflöresans gösterdiği izlendi. OKT kesitlerinde sızıntı bölgesinde izlenen retina pigment epitel düzensizliklerinin otoflöresans görüntülemede hipootoflöresan alanlar olarak izlendi. Sonuç: Normal retinada diskler halindeki fotoreseptör dış segmentleri zamanla potansiyel boşluk olan subretinal alana dökülür ve RPE tarafından bu diskler fagosite edilirler. RPE ile fotoreseptör dış segmentlerinin birbirinden uzaklaşmasına neden olan SSKR’de dış segmentler uzamaya ve dökülmeye devam etmesine rağmen RPE tarafından fagosite edilemezler. OKT ve otoflöresans görüntüleme teknikleri ile bu granüler birikimleri non invaziv bir şekilde tespit etmek mümkündür.

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Cite This Article

AYATA, A., KAR, T., ÜNAL, M., ERŞANLI, D. (2009). Optic coherence tomography and autofluorescence findings in chronic central serous chorioretinopathy. Retina-Vitreus, Cilt: 17 - Sayı: 1, 9–13. https://ajindex.com/articles/305179

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