Journals / Retina-Vitreus / 2013 / Cilt: 21 - Sayı: 3

Non-hodgkin lenfomalı bir olguda nüks sitomegalovirüs retiniti

Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma

Pages
231–233
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, we recommend at least six months ganciclovir therapy for such cases to prevent the recurrence of the disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 30-year-old female patient presented at our clinic suffering from decreasing vision in the left eye for the last 2 weeks.
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Key Findings & Data:According to the patient file, she had been started on chemotherapy six months ago due to a diagnosis of stage 4 peripheral T-cell non-Hodgkin’s lymphoma.
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Conclusion & Impact:In conclusion, we recommend at least six months ganciclovir therapy for such cases to prevent the recurrence of the disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 30-year-old female patient presented at our clinic suffering from decreasing vision in the left eye for the last 2 weeks. According to the patient file, she had been started on chemotherapy six months ago due to a diagnosis of stage 4 peripheral T-cell non-Hodgkin’s lymphoma. There was common vascular sheathing with an appearance of typical frosted branch an- giitis and white retinal lesions related to retinal hemorrhages in the right eye on fundoscopic examination. The left retina was hazy on fundoscopic examination but exudative lesions were observed around the optic disc and macula and on the peripheral retina. HIV and CMV IgM tests were negative on serological tests, but the CMV IgG test was positive. CMV retinitis was diagnosed and intravenous ganciclovir administered as the treatment. Ganciclovir was stopped after 4 months, but CMV retinitis recurred in both eyes two weeks later. The patient was transferred to the hematology service as he was in poor general condition but later passed away. In conclusion, we recommend at least six months ganciclovir therapy for such cases to prevent the recurrence of the disease.

Özet

Otuz yaşındaki kadın hasta sol gözünde 2 haftadır görme azalması şikayeti ile kliniğimize başvurdu. Hastanın hikayesin- den 6 ay önce evre 4 periferal T-hücreli non-Hodgkin lenfoma tanısı ile kemoterapi görmeye başladığı öğrenildi. Fundosko- pik muayenede sağ gözde tipik donmuş ağaç dal anjitisi görünümünde yaygın vasküler kılıflanma ve retinal hemorajilerle ilişkili beyaz retinal lezyonlar mevcuttu. Sol göz fundoskopik muayenede retina flue olarak değerlendirilmekle birlikte optik disk çevresinde ve periferik retina da eksudatif lezyonlar görülmekteydi. Serolojik testler HIV ve CMV Ig M testi negatif, CMV Ig G positif olarak sonuçlandı. Hastaya CMV retiniti tanısı konularak intravenöz gansiklovir tedavisi başlanıldı. Gansiklovir 4 ay sonra kesildi, ancak 2 hafta sonra her iki gözde CMV retiniti nüks etti. Genel durumu bozuk olan hasta hematoloji servisine transfer edildi ancak hasta kaybedildi. Sonuç olarak, bu tür olgularda hastalığın nüksetmemesi için en az 6 ay gansiklovir tedavisi önermekteyiz.

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Cite This Article

ÇETİN, A. B., KILIÇ, R., GÖKTOLGA, G., DEMİR, S., ÜSTÜN, S. Ç., ÇAKMAK, Y. (2013). Non-hodgkin lenfomalı bir olguda nüks sitomegalovirüs retiniti. Retina-Vitreus, Cilt: 21 - Sayı: 3, 231–233. https://ajindex.com/articles/305114

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