Ön üveitli gözlerde maküler kalınlaşma

Objective & Hypothesis:Purpose: To investigate pre- and post-treatment macular and peripapillary nerve fiber layer (RNFL) changes in eyes with acute anterior uveitis (AU) by optical coherence tomography (OCT).

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Key Findings & Data:Materials and Methods: Seventeen eyes of 17 patients with AU (uveitic eyes) and unaffected fellow (control) eyes of these patients were enrolled to the study.

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Conclusion & Impact:OCT devices may be useful for noninvasive evaluation of microscopic macular changes that are not yet obvious in a standard clinical examination.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Purpose: To investigate pre- and post-treatment macular and peripapillary nerve fiber layer (RNFL) changes in eyes with acute anterior uveitis (AU) by optical coherence tomography (OCT). Materials and Methods: Seventeen eyes of 17 patients with AU (uveitic eyes) and unaffected fellow (control) eyes of these patients were enrolled to the study. Peripapillary RNFL, optic nerve head, and macular scans were performed using Cirrus HD OCT. OCT measurements were performed at baseline (before starting treatment) and two months after the remission for each subject. Results: The mean age of the patients was 32.0±12.3 years. Uveitic eyes had significantly higher central subfield thickness (CST) values than healthy fellow control eyes (p=0.010). CST decreased significantly after the treatment compared with baseline (p=0.001) in the uveitic eyes, whereas there was no significant difference between pre- and post-treatment CST values of healthy fellow control eyes. Conclusions: We have shown that eyes with AU had higher CST than healthy fellow eyes in Cirrus HD OCT. OCT devices may be useful for noninvasive evaluation of microscopic macular changes that are not yet obvious in a standard clinical examination.

Özet

Amaç: Ön üveitli gözlerin tedavi öncesi ve sonrası maküler ve peripapiller retinal sinir lifi tabakası (RSLT) değişiklikleri- nin optik koherens tomografi (OKT) ile araştırılması. Gereç ve Yöntem: On yedi ön üveitli hastanın üveitli gözleri ile sağlıklı diğer gözleri (kontrol) çalışmaya dâhil edildi. Te- davi öncesi ve remisyon sonrası 2. ay peripapiller RSLT, optik sinir başı ve maküler ölçümler Cirrus HD OKT kullanılarak yapıldı. Bulgular: Hastaların yaş ortalaması 32.0±12.3 idi. Üveitli gözler sağlıklı control gözlerine göre anlamlı olarak daha yüksek santral subfield kalınlık (CST) değerlerine sahipti (p=0.010). Üveitli gözlerde CST tedavi sonrası anlamlı derecede düşer- ken, sağlıklı control gözlerde tedavi öncesi ve sonrası CST değerleri arasında fark yoktu. Sonuçlar: Bu çalışmada Cirrus HD OKT ile yapılan ölçümlerde ön üveitli gözlerin sağlıklı kontrol gözlere göre anlamlı derecede yüksek CST değerlerine sahip olduğunu gösterdik. OKT cihazları ön üveitli gözlerde klinik muayene ile tespit edilemeyen mikroskopik değişikliklerin invaziv olmayan yöntemle saptanması için kullanılabilir.

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Cite This Article

ÖNER, V., TÜRKYILMAZ, K., KÜÇÜKALİ, A. T., GEDİZ, B. Ş., DURMUŞ, M. (2013). Ön üveitli gözlerde maküler kalınlaşma. Retina-Vitreus, Cilt: 21 - Sayı: 3, 193–196. https://ajindex.com/articles/305111

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