Journals / Retina-Vitreus / 2014 / Cilt: 22 - Sayı: 4

Evaluation of retrobulber flow parameters in non proliferatif diabetic retinopathy with color doppler ultrasonography

Non proliferatif diyabetik retinopatide retrobulber akım parametrelerinin renkli doppler ultrasonografi ile değerlendirilmesi

Pages
273–278
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: We found that increasing duration of DM and higher HbA1c levels increased vascular resistance and reduced retrobulber flow.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: Evaluation of retrobulber flow parameters in cases which have early stage diabetic retinopathy with color doppler ultrasonography Material and Methods: In our study we examined a total of 90 subjects consist of 60 type 2 diabetic patients and 30 healty controls.
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Key Findings & Data:All patient’s fasting blood glucose level before doppler ultrasonography, HbA1c, LDL, HDL levels, duration of dia- betes mellitus (DM), systolic/diastolic and mean blood pressure were recorded.
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Conclusion & Impact:Conclusion: We found that increasing duration of DM and higher HbA1c levels increased vascular resistance and reduced retrobulber flow.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: Evaluation of retrobulber flow parameters in cases which have early stage diabetic retinopathy with color doppler ultrasonography Material and Methods: In our study we examined a total of 90 subjects consist of 60 type 2 diabetic patients and 30 healty controls. All patient’s fasting blood glucose level before doppler ultrasonography, HbA1c, LDL, HDL levels, duration of dia- betes mellitus (DM), systolic/diastolic and mean blood pressure were recorded. Visual acuity, intraoculer pressure, anterior segment examination were done all patients. Diabetic patients were divided into 2 groups according to the degree of diabetic retinopathy. Diabetic patients without retinopathy (group 2) and mild non proliferatif diabetic retinopathy (group 3) were classified. The peak systolic (Vmax) and diastolic blood flow (Vmin), resistivity index (RI) and pulsatility index (PI) of oph- talmic artery (OA), central retinal artery (CRA), short posterior ciliary artery (SPSA) were measured. Results: In group 3 fasting blood glucose level before doppler ultrasonography, HbA1c, LDL, HDL levels, duration of DM were significantly higher than control and group 2. Vmax and Vmin was lower and mean RI was higher in the diabetic reti- nopathy than control group regarding the OA, CRA, SPSA. Vmax and Vmin was lower and mean RI was higher in group 2 than group 3. There was significantly positive corelation between OA-RI and HbA1c values and duration of DM. Conclusion: We found that increasing duration of DM and higher HbA1c levels increased vascular resistance and reduced retrobulber flow.

Özet

Amaç: Erken evre diyabetik retinopatili olgularda retrobuleber kan akım parametrelerini renkli doppler ultrasonografi ile değerlendirmek. Gereç ve Yöntem: Çalışmaya 60 tip 2 diyabetli hasta ve 30 sağlıklı birey toplam 90 birey alındı. Tüm hastaların tam kan, hemoglobin, hematokrit, kan LDL, HDL, sistolik/diyastolik ve ortalama kan basınçları, diyabetik hastalarda, HbA1c, renkli doppler ultrasonografi (RDUS) öncesi açlık kan glukoz değerleri, diyabet süresi kaydedildi. Tüm hastaların görme keskin- likleri, göz içi basınçları, ön segment muayeneleri yapıldı. Diyabetik gruptaki hastalar diyabetik retinopatisi olmayanlar (Grup 2) ve hafif-orta derecede non-proliferatif diyabetik retinopatisi (NPDR) olanlar (Grup 3) olarak sınıflandırıldı. Tüm olguların oftalmik arter (OA), santral retinal arter (SRA), kısa posterior siliyer arter (KPSA) sistolik (Vmax) ve diastolik (Vmin) akım hızları, rezistivite indeksi (Rİ) ve pulsatilite indeksleri (Pİ) renkli doppler ile değerlendirildi. Bulgular: Grup 3’te diğer iki gruba göre, DM süresi, HbA1c düzeyi, LDL, ortalama kan basıncı, ölçüm öncesi kan glukoz düzeyi değerleri daha yüksek bulundu (p<0.05). OA, SRA ve KPSA’daki akım hızları diyabetik grupta kontrol grubuna göre düşük, direnç indeksleri yüksek bulundu. Diyabetik grup kendi arasında değerlendirildiğinde retinopatili olgularda retinopatisiz gruba göre akım hızlarının azalmış, direnç indekslerinin artmış olduğu tespit edildi. Sonuç: Diyabetik retinopatide artan diyabet süresi ve yüksek HbA1c düzeylerinin damar direncini arttırdığı ve retrobulber kan akım hızlarını azalttığı tespit edildi. Erken evre diyabetik retinopatide OA-RI değerlerinin diyabetik retinopatinin progresyonun takibinde kullanılabileceği sonucuna varıldı.

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Cite This Article

EKMEN, M. R., YEŞİLKAYA, Y., KOÇAK, A. G. A. (2014). Evaluation of retrobulber flow parameters in non proliferatif diabetic retinopathy with color doppler ultrasonography. Retina-Vitreus, Cilt: 22 - Sayı: 4, 273–278. https://ajindex.com/articles/305022

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