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Journals / Retina-Vitreus / 2014 / Cilt: 22 - Sayı: 3

Evaluation of choroidal thickness by using optical coherence tomography in healthy individuals

Toplumumuzda sağlıklı bireylerde optik koherens tomografi ile koroidal pleksus kalınlık değerlendirilmesi

Mustafa GÖK
Mehmet Ş. ASLAN
V. Levent KARABAŞ
Pages
184–188
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this way, the EDI OCT setting out these changes can be a good instrument to follow.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: To evaluate subfoveal choroidal thickness in healthy Turkish subjects with wide age range by using optical coher- ence tomography (OCT).
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Key Findings & Data:Materials and Methods: In this retrospective study, we evaluated 478 eyes of 239 healthy individuals.
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Conclusion & Impact:In this way, the EDI OCT setting out these changes can be a good instrument to follow.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate subfoveal choroidal thickness in healthy Turkish subjects with wide age range by using optical coher- ence tomography (OCT). Materials and Methods: In this retrospective study, we evaluated 478 eyes of 239 healthy individuals. The age range was (10-83) years. Subfoveal choroidal thickness (SFCT) measurements was performed with spectral-domain OCT in EDI (enhanced depth imaging) mode. Age and OCT measurements was assessed by Pearson correlation analysis and regression analysis. Results: Subfoveal choroidal thickness (SFCT) measurements showed a significant negative correlation with age. (p<0.001, r=-0.578). The regression analysis showed that a 1.797 milimicron SFCT reduction for the increase each year of age. Conclusions: Similar to age-related SFCT decrease, choroidal vascular bed-as well as other microvascular tissues-may be influenced by structural changes in the aging process. In this way, the EDI OCT setting out these changes can be a good instrument to follow.

Özet

Amaç: Toplumumuzda geniş yaş aralığında, sağlıklı bireylerde optik koherens tomografi (OKT) ile subfoveal koroid kalın- lığı analizi. Gereç ve Yöntem: Bu geriye dönük çalışmada, 239 sağlıklı bireyin 478 gözü değerlendirildi. Yaş aralığı (10-83) olan sağ- lıklı bireylerde subfoveal koroid kalınlığı (SKK) ölçümleri spektral domain OKT ile EDI (enhanced depth imaging) modunda yapıldı. Yaş ve OKT ölçümleri pearson korelasyon analizi ve regresyon analizi ile değerlendirildi. Bulgular: Subfoveal koroid kalınlığı (SKK) ölçümleri ile yaş arasında anlamlı negatif korelasyon saptandı. (p<0.001, r=-0.578). Yapılan regresyon analizinde ortalama SKK için her yaş artışına karşılık 1.797 milimikronluk bir azalma tespit edildi. Sonuç: Yaşa bağlı SKK azalması ile birlikte koroidal vasküler yatağın vücuttaki diğer mikrovasküler dokulardaki gibi yaşlanma sürecindeki yapısal değişikliklerden etkileniyor olabileceği kanaatine varıldı. Bu sayede bu değişimleri ortaya koymada EDI OKT iyi bir takip enstrümanı olabilir.

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Cite This Article

GÖK, M., ASLAN, M. Ş., KARABAŞ, V. L. (2014). Evaluation of choroidal thickness by using optical coherence tomography in healthy individuals. Retina-Vitreus, Cilt: 22 - Sayı: 3, 184–188. https://ajindex.com/articles/305014

References (15)

  1. Bill A, Tornquist P, Alm A. Permeability of the intraocular blood vessels. Trans. Ophthalmol. Soc. U. K. 1980
  2. Chan-Ling T, Koina ME, McColm JR, et al. Role of CD44+ stem cells in mural cell formation in the human cho- roid: evidence of vascular instability due tolimited pericyte en- sheathment. Invest. Ophthalmol Vis Sci 2011
  3. Bruun A, Ehinger B, Sundler F, et al. immunoreactive neu- rons in the guinea-pig uvea and retina. Invest. Ophthalmol Vis Sci 1984
  4. Bill A, Sperber GO. Control of retinal and choroidal blood flow. Eye (Lond) 1990
  5. Alm A. The effect of sympathetic stimula- tion on blood flow throught, e uvea, retina and optic nerve in monkeys (Macaccairus). Exp Eye Res 1977
  6. Kawarai M, Koss MC. Sympathetic vasoconstriction in the rat anterior choroid is mediated by alpha1-adrenoceptors. Eur J Pharmacol 1998
  7. Nilsson SF. Nitric oxide as a mediator of parasympathet- ic vasodilation in ocular and extraocular tissues in the rab- bit. Invest Ophthalmol Vis Sci 1996
  8. de Hoz R, Ramírez AI, Salazar JJ, et al. Substance P and cal- citonin gene-related peptide intrinsic choroidal neu- rons in human choroidal whole-mounts. Histol Histopathol 2008
  9. Spaide RF, Koizumi H, Pozzoni MC. Enhanced depth imaging spectral-domain optical coherence tomography. Am J Oph- thalmol 2008
  10. Chhablani J, Barteselli G, Wang H, et al. Repeatabil- ity and reproducibility of manual choroidalvolume mea- surements using enhanced depth imagingoptical coher- ence tomography. Invest Ophthalmol Vis Sci 2012
  11. Ikuno Y, Maruko I, Yasuno Y, et al. Reproducibility of retinal and choroidal thickness measurements in enhanced depth im- aging and high-penetration optical coherence tomography. In- vest Ophthalmol Vis Sci 2011
  12. Margolis R, Spaide RF. A pilot study of enhanced depth im- aging opti­cal coherence tomography of the choroid in normal eyes. Am J Oph­thalmol 2009
  13. Goldenberg D, Moisseiev E, Goldstein M, et al. En- hanced depth imaging optical coherence tomography: choroidal thickness and correlations with age, refractive error, and axial length.Ophthalmic Surg Lasers Imaging 2012
  14. Tan CS, Ouyang Y, Ruiz H, et al. Diurnal variation of choroi- dal thickness in normal, healthy subjects measured by spec- tral domainoptical coherence tomography.Invest Ophthalmol Vis Sci 2012
  15. Yamazaki T, Koizumi H, Yamagishi T,