AI Summary & Key Takeaways
AI InsightCT (?m) was signifi cantly thinner in the eyes of patients with migraine at the fovea (270.47 ± 36.29 ?m), temporal (251.72 ± 35.09) and nasal (237.83 ± 32.86) region of the fovea (p< 0.05) in comparison with control group (290.44 ± 39.27, 270.47 ± 38.51, 256.97 ± 35.68).Conclusions: Migraine leads to thinning of the TL,TU, IN and mean RNFL thickness and CT.
📌 3 Key Takeaways
Abstract
Purpose: To compare the choroidal thickness (CT) and retinal nerve fi ber layer (RNFL) thickness in patients with migraine and healthy controls, using wide fi eld en face optical coherence tomography (OCT).Materials and Methods: This prospective study included 36 eyes of 36 patients in the migraine group and 36 healthy cases as control subjects. The RNFL thickness was analyzed with OCT protocol while CT was analyzed with Enhanced depth imaging (EDI) protocol in all subjects. CT was measured at the fovea, 1500 ?m nasal and 1500 ?m temporal to the fovea in a horizontal section. The values were compared in both groups. T-test was used as statistical analysis. p <0.05 values considered statistically signifi cant. Results: The mean RNFL thickness (?m) in the eyes of patients with migraine for temporal-upper (TU) (78.1 ± 7.2), temporal-lower (TL) (63.7 ± 5.) and infero-nasal (IN) (100.5 ± 10.8) sectors was signifi cantly thinner than the control group TU (89.3 ± 7.8), TL (75.9 ± 7.4) and IN (116.3 ± 12.1) sectors (p=.000). The mean RNFL thickness (?m) was signifi cantly thinner than in migraine patients (100.5 ± 9.1) compared to controls (109.6 ± 12.1). CT (?m) was signifi cantly thinner in the eyes of patients with migraine at the fovea (270.47 ± 36.29 ?m), temporal (251.72 ± 35.09) and nasal (237.83 ± 32.86) region of the fovea (p< 0.05) in comparison with control group (290.44 ± 39.27, 270.47 ± 38.51, 256.97 ± 35.68).Conclusions: Migraine leads to thinning of the TL,TU, IN and mean RNFL thickness and CT.
Özet
Amaç: Migren hastalarında wide fi eld en face optik koherens tomografi (OKT) kullanarak ölçülen koroid kalınlığı (KK) ve retina sinir lifi kalınlığının (RSLTK) sağlıklı kontrol grubu ile karşılaştırılması.Gereç ve Yöntem: Migreni olan 36 hastanın 36 gözü ve kontrol grubu olarak 36 sağlıklı olgu prospektif olarak çalışmaya dahil edildi. Tüm olgularda KK "Enhanced depth imaging" (EDİ) protokolü ile analiz edilirken RSLTK OKT protokolü ile analiz edildi. KK fovea altında, yatay düzlemde fovea merkezinin 1500 mikron nazal ve 1500 mikron temporal bölümünde ölçüldü. her iki gruptaki değerler karşılaştırıldı. İstatistik yöntem olarak t-testi kullanıldı. p< 0.05 olan değerler istatiksel olarak anlamlı kabul edildi. Bulgular: Migrenli hastalarda temporal-üst (TÜ) (78.1 ± 7.2) ve temporal -alt (TA) (63.7 ± 5.1) ve infero-nazal (İN) (100.5 ± 10.8) ortalama RSLTK (?m), kontrol grubuna göre TÜ (89.3 ± 7.8), TA (75.9 ± 7.4), İN (116.3 ± 12.1) anlamlı şekilde inceydi (p=.000). Ortalama RSLTK (?m) migrenli hastalarda (100.5 ± 9.1) kontrol grubuna (109.6 ± 12.1) kıyasla daha inceydi (p=.001). Ortalama KK (?m) migrenli hastalarda foveada (270.47 ± 36.29), fovea temporali (251.72 ± 35.09) ve fovea nazalinde (237.83 ± 32.86) kontrol grubuna göre (290.44 ± 39.27, 270.47 ± 38.51, 256.97 ± 35.68) anlamlı şekilde inceydi (p< 0.05).Tartışma: Migren TA, TÜ, İN ve ortalama RSLTK ve KK'da incelmeye yol açmaktadır.