Journals / Retina-Vitreus / 2019 / Cilt: 28 - Sayı: 3

Ocular and Cerebral Blood Flow Analysis in Cases with Retinopathy of Prematurity

Prematüre Retinopatisi Olgularında Oküler ve Serebral Kan Akım Analizi

Pages
234–238
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: There were signifi cant changes of ocular and cerebral blood fl ow parameters between premature infants with Zon 2 stage 3 ROP with plus disease and premature infants who did not have ROP and/or plus disease.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To compare ocular and cerebral blood fl ow parameters between infants who had retinopathy of prematurity (ROP) with plus disease and infants who did not have any sign of ROP and plus disease.
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Key Findings & Data:Materials and Methods: A total of 33 cases were studied.
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Conclusion & Impact:Conclusion: There were signifi cant changes of ocular and cerebral blood fl ow parameters between premature infants with Zon 2 stage 3 ROP with plus disease and premature infants who did not have ROP and/or plus disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To compare ocular and cerebral blood fl ow parameters between infants who had retinopathy of prematurity (ROP) with plus disease and infants who did not have any sign of ROP and plus disease. Materials and Methods: A total of 33 cases were studied. Group 1 included 23 infants who had Zon 2 stage 3 ROP with plus disease, group 2 included 10 infants who did not have ROP and/or plus disease. Ophthalmic artery (OA) and median cereabral artery (MCA) were evaluated during measurements. Peak systolic velocity (PSV), end-diastolic velocity (EDV), mean velocity (MV), pulsatility index (PI) and resistivity index (RI) were recorded. Results: Gestational age and birth weight did not signifi cantly differ between the groups (p=0.69, p=0.91, respectively). For OA; PSV, EDV, MV, PI and RI values were 45.35±14.25 cm/s, 7.83±4.14 cm/s, 19.00±4.35 cm/s, 0.64±0.13 and 0.83±0.07 in group 1, 37.40±5.02 cm/s, 9.70±1.49 cm/s, 18.68±3.38 cm/s, 0.48±0.06 and 0.71±0.11 in group 2, respectively. TSH (p=0.034), Pİ (p<0.001) and Rİ (p<0.001) in OA did signifi cantly differ between the groups. For MCA; PSV, EDV, MV, PI and RI values were 62.60±13.46 cm/s, 13.43±4.30 cm/s, 31.91±7.22 cm/s, 0.58±0.12 and 0.77±0.07 in group 1, 68.70±20.41, 19.60±8.36, 38.40±13.59, 0.51±0.08 and 0.71±0.06 in group 2, respectively. EDV (p=0.008) and RI (p=0.028) in MCA did signifi cantly differ between the groups. Conclusion: There were signifi cant changes of ocular and cerebral blood fl ow parameters between premature infants with Zon 2 stage 3 ROP with plus disease and premature infants who did not have ROP and/or plus disease.

Özet

Amaç: Prematüre retinopatisi (ROP) ve plus gelişen bebekler ile ROP ve plus mevcut olmayan prematüre bebeklerin oküler ve serebral kan akım değerlerini karşılaştırmak. Gereç ve Yöntemler: Çalışmaya toplamda 33 olgu dahil edildi. Grup 1’de Zon 2 evre 3 ROP ve plus mevcut olan 23 olgu, Grup 2’de ise ROP ve/veya plus bulgusu olmayan 10 olgu mevcut idi. Ölçümlerde Oftalmik arter (OA) ve median serebral arter (MSA) değerlendirildi. Tepe sistolik hız (TSH), end-diastolik hız (EDH), ortalama hız (OH), pulsatilite indeksi (Pİ) ve rezistif indeks (Rİ) değerleri kaydedildi. Bulgular: Gruplar arasında ortalama doğum haftası ve doğum ağırlığı yöünden anlamlı fark yoktu (sırasıyla, p=0,69, p=0,91). Oftalmik arter için TSH, EDH, OH, Pİ ve Rİ değerleri grup 1’de sırası ile 45,35±14,25 cm/s, 7,83±4,14 cm/s, 19,00±4,35 cm/s, 0,64±0,13 ve 0,83±0,07 iken; grup 2’de sırası ile 37,40±5,02 cm/s, 9,70±1,49 cm/s, 18,68±3,38 cm/s, 0,48±0,06 ve 0,71±0,11 idi. İki grup arasında OA’da TSH (p=0,034), Pİ (p<0,001) ve Rİ (p<0,001) değerleri yönünden anlamlı farklılık mevcuttu. Median serebral arter için TSH, EDH, OH, Pİ ve Rİ değerleri grup 1’de sırası ile 62,60±13,46 cm/s, 13,43±4,30 cm/s, 31,91±7,22 cm/s, 0,58±0,12 ve 0,77±0,07 iken; grup 2’de 68,70±20,41, 19,60±8,36, 38,40±13,59, 0,51±0,08 ve 0,71±0,06 idi. İki grup arasında MSA’da EDH (p=0,008) ve Rİ (0,028) yönünden anlamlı farklılık mevcuttu. Sonuç: Plus hastalık eşliğinde Zon 2 evre 3 ROP olan prematüre olgularda, ROP ve/veya plus bulgusu olmayan prematüre olgulara göre oküler ve serebral kan akım değerlerinde anlamlı değişimler gözlenmektedir. Plus bulgusu varlığı bu bulgunun ortaya çıkmasında önemli rol oynamaktadır.

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Cite This Article

GÜNAY, M., ÇELİK, G., TUTEN, A. (2019). Ocular and Cerebral Blood Flow Analysis in Cases with Retinopathy of Prematurity. Retina-Vitreus, Cilt: 28 - Sayı: 3, 234–238. https://ajindex.com/articles/304818

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