Journals / Retina-Vitreus / 2019 / Cilt: 28 - Sayı: 3

Optical Coherence Tomography Angiography Findings Before and After Photodynamic Therapy in Chronic Central Serous Chorioretinopathy: Report of Two Cases

Kronik Santral Seröz Koryoretinopatide Fotodinamik Tedavi Öncesi ve Sonrası Erken Dönem Optik Koherens Tomografi Anjiografi Bulguları: İki Olgu Sunumu

Pages
306–309
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion OCTA is a fast and reproducible technique that allows the evaluation of retinal and choroidal vasculature noninvasively.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to evaluate the changes of the fi ndings in optical coherence tomography angiography (OCTA) of two cases with chronic central serous chorioretinopathy (CSCR) before and after photodynamic therapy (PDT).
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Key Findings & Data:Retinal and choroidal vasculature changes of two cases diagnosed with chronic CSCR of whom the duration of the symptoms were longer than 6 months and were decided to receive PDT were evaluated with OCTA before treatment and at 1 month follow-up.
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Conclusion & Impact:In conclusion OCTA is a fast and reproducible technique that allows the evaluation of retinal and choroidal vasculature noninvasively.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aim of this study was to evaluate the changes of the fi ndings in optical coherence tomography angiography (OCTA) of two cases with chronic central serous chorioretinopathy (CSCR) before and after photodynamic therapy (PDT). Retinal and choroidal vasculature changes of two cases diagnosed with chronic CSCR of whom the duration of the symptoms were longer than 6 months and were decided to receive PDT were evaluated with OCTA before treatment and at 1 month follow-up. Choroidal vascular permeability is known to be increased in chronic CSCR. In both cases OCTA showed hyperrefl ectivity refl ecting the changes in vascular structures before treatment. In the OCTA imagings, at the fi rst month of treatment the vascular permeability and hyperrefl ectivity is shown to be decreased. In conclusion OCTA is a fast and reproducible technique that allows the evaluation of retinal and choroidal vasculature noninvasively. Choroidal vasculature changes after PDT can be evaluated in details with OCTA in cases with CSCR.

Özet

Bu çalışmada kronik santral seröz koryoretinopatili (SSKR) iki olguda fotodinamik tedavi (FDT) öncesi ve sonrası optik koherens tomografi anjiografi (OKTA) bulgularındaki değişiklikleri değerlendirmek amaçlanmıştır. Bulguları 6 aydan daha uzun süredir devam eden kronik SSKR tanısı almış ve FDT kararı verilmiş iki olgunun tedavi öncesinde ve tedaviden 1 ay sonraki kontrollerinde OKTA testleri tekrarlanarak, olguların retinal ve koroidal damarlarındaki değişiklikler değerlendirildi. Kronik SSKR’de koroidal vasküler geçirgenliğin arttığı bilinmektedir. Her iki olguda tedavi öncesi yapılan OKTA’da koroidal vasküler yapılardaki değişikliği gösteren hiperrefl ektivite saptanmıştır. FDT’den 1 ay sonra yapılan OKTA görüntülemesinde ise bu vasküler geçirgenliğin ve hiperrefl ektivitenin azaldığı görülmektedir. Sonuç olarak OKTA noninvaziv olarak retinal ve koroidal damar yapısının değerlendirilmesini sağlayan hızlı ve tekrarlanabilir bir tetkiktir. Kronik SSKR’li olgularda FDT sonrasında koroidal kan dolaşımında oluşan değişiklikler OKTA ile ayrıntılı bir şekilde değerlendirilebilmektedir.

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Cite This Article

SEVİM, D. G., ÖNER, A., ÜNLÜ, M. (2019). Optical Coherence Tomography Angiography Findings Before and After Photodynamic Therapy in Chronic Central Serous Chorioretinopathy: Report of Two Cases. Retina-Vitreus, Cilt: 28 - Sayı: 3, 306–309. https://ajindex.com/articles/304809

References (3)

  1. Nassisi M, Lavia C, Alovisi C, et al. Short-Term Choriocapillaris Changes in Patients with Central Serous Chorioretinopathy after Half-Dose Photodynamic Therapy. Int J Mol Sci. 2017;18(11). doi: 10.3390/ijms18112468 Nicholson B, Noble J, Forooghian F, et al. Central serous chorioretinopathy: update on pathophysiology and treatment. Surv Ophthalmol. 2013;58(2):103-26. doi: 10.1016/j.survophthal.2012.07.004 Schlotzer-Schrehardt U, Viestenz A, Naumann GO, et al. Doserelated structural effects of photodynamic therapy on choroidal and retinal structures of human eyes. Graefes Arch Clin Exp Ophthalmol. 2002;240(9):748-57. doi: 10.1007/s00417-002-0517-4
  2. Jia Y, Tan O, Tokayer J, et al. Split-spectrum amplitudedecorrelation angiography with optical coherence tomography. Opt Express. 2012;20(4):4710-25. doi: 10.1364/OE.20.004710 Quaranta-El Maftouhi M, El Maftouhi A, Eandi CM. Chronic central serous chorioretinopathy imaged by optical coherence tomographic angiography. Am J Ophthalmol. 2015;160(3):581-7 e1. doi: 10.1016/j.ajo.2015.06.016 Chan SY, Wang Q, Wei WB, et al. Optical Coherence Tomographic Angiography in Central Serous Chorioretinopathy. Retina. 2016;36(11):2051-8. doi: 10.1097/IAE.0000000000001064 Cardillo Piccolino F, Eandi CM, Ventre L, et al. Photodynamic therapy for chronic central serous chorioretinopathy. Retina. 2003;23(6):752-63. doi, https://www.ncbi.nlm.nih.gov/pubmed/14707823
  3. Chan WM, Lam DS, Lai TY, et al. Treatment of choroidal neovascularization in central serous chorioretinopathy by photodynamic therapy with verteporfi n. Am J Ophthalmol. 2003;136(5):836-45. doi, https://www.ncbi.nlm.nih.gov/ pubmed/14597034 Xu Y, Su Y, Li L, et al. Effect of Photodynamic Therapy on Optical Coherence Tomography Angiography in Eyes with Chronic Central Serous Chorioretinopathy. Ophthalmologica. 2017;237(3):167-72. doi: 10.1159/000456676 Fujita K, Kawamura A, Yuzawa M. Choriocapillaris Changes Imaged by OCT Angiography After Half-Dose Photodynamic Therapy for Chronic Central Serous Chorioretinopathy. Ophthalmic Surg Lasers Imaging Retina. 2017;48(4):302-10. doi: 10.3928/23258160-20170329-04