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Journals / Retina-Vitreus / 2020 / Cilt: 29 - Sayı: 1

Posterior Segment Effects of Prostaglandin Analogues

Neslihan SINIM
Sarper KARAKÜÇÜK
Pages
30–34
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

PG analogue therapy should be kept in mind in clinical conditions where choroidal thickness is signifi cant.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: Prostaglandin (PG) analogues are commonly used in the treatment of glaucoma.
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Key Findings & Data:Materials and Methods: Patients diagnosed with POAG and treated for 1 to 3 years were included in the study.
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Conclusion & Impact:PG analogue therapy should be kept in mind in clinical conditions where choroidal thickness is signifi cant.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Purpose: Prostaglandin (PG) analogues are commonly used in the treatment of glaucoma. In this study, we aimed to investigate the posterior segment effects of the drug with long-term use of topical PG analogue monotherapy in patients with the diagnosis of primary open angle glaucoma (POAG). Materials and Methods: Patients diagnosed with POAG and treated for 1 to 3 years were included in the study. A total of 25 patients treated with latanoprost monotherapy formed the 1st group, 25 patients who received dorzolamide timolol combination monotherapy constituted the 2nd group, 25 patients with brimonidine monotherapy formed the 3rd group and 31 healthy volunteers made up the 4th group. Routine ophthalmological examination, intraocular pressure (IOP) measurement and fundus examinations were performed thoroughly. Central macular and choroidal thicknesses were measured by optical coherence tomography (OCT). Results: There was no signifi cant difference in the mean macular thickness between the groups. The mean choroidal thickness was signifi cantly higher in patients using PG analogue than the other groups. None of the patients had intraocular infl ammation or cystoid macular edema (CME). Conclusion: The choroidal thickness was signifi cantly higher in the group receiving topical latanoprost monotherapy than the other groups. None of the patients had CME or infl ammation. PG analogue monotherapy can be used safely in POAG cases. PG analogue therapy should be kept in mind in clinical conditions where choroidal thickness is signifi cant.

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Cite This Article

SINIM, N., KARAKÜÇÜK, S. (2020). Posterior Segment Effects of Prostaglandin Analogues. Retina-Vitreus, Cilt: 29 - Sayı: 1, 30–34. https://ajindex.com/articles/304783

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