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Journals / Psychiatry and behavioral sciences (Online) / 2020 / Cilt: 10 - Sayı: 2

Increased of Platelet Indices in Patients with Attention Deficit/ Hyperactivity Disorder

Sinan AKBAYRAM
Cem GÖKÇEN
Mehmet Ali KARADAĞ
Pages
86–89
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although the significance and cause of increased MPV, PDW, and PCT levels in ADHD remain unclear in our study, further studies are warranted to investigate relationships among MPV, PDW, PCT levels, ADHD in children.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The relationship between platelet activation and psychiatric disorders has been previously investigated by several studies.
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Key Findings & Data:Methods: The records of a total of 47 children with ADHD (aged 6-16 years), diagnosed using the DSM-V, have been scanned.
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Conclusion & Impact:Although the significance and cause of increased MPV, PDW, and PCT levels in ADHD remain unclear in our study, further studies are warranted to investigate relationships among MPV, PDW, PCT levels, ADHD in children.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objective: The relationship between platelet activation and psychiatric disorders has been previously investigated by several studies. The aim of the present study was to investigate any probable difference in the platelet indices of patients with attention deficit/hyperactivity disorder(ADHD). Methods: The records of a total of 47 children with ADHD (aged 6-16 years), diagnosed using the DSM-V, have been scanned. The study consisted of 47 patients, who were admitted to our hospital, and 50 healthy controls (aged 6-16 years). Platelet indices, including platelet count, MPV, PDW, and PCT levels were retrospectively recorded. Results: The MPV, PDW and PCT values in the ADHD group were found to be increased significantly compared to those of the healthy control group. (p<0.001). Conclusion: Platelet indices may be important to display ADHD’s etiology. Although the significance and cause of increased MPV, PDW, and PCT levels in ADHD remain unclear in our study, further studies are warranted to investigate relationships among MPV, PDW, PCT levels, ADHD in children.

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Cite This Article

AKBAYRAM, S., GÖKÇEN, C., KARADAĞ, M. A. (2020). Increased of Platelet Indices in Patients with Attention Deficit/ Hyperactivity Disorder. Psychiatry and behavioral sciences (Online), Cilt: 10 - Sayı: 2, 86–89. https://ajindex.com/articles/302873

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References (9)

  1. Association AP. Diagnostic and statistical manual of mental disorders (DSM-5®): American Psychiatric Pub; 2013. Biederman J. Attention-deficit/hyperactivity disorder: a selective overview. J Biological Psychiatry. 2005;57(11):1215- 20. Yorbik O, Mutlu C, Tanju IA, Celik D, Ozcan O. Mean platelet volume in children with attention deficit hyperactivity disorder. J Medical Hypotheses. 2014;82(3):341-5.
  2. Camacho A, Dimsdale JE. Platelets and psychiatry: lessons learned from old and new studies. J Psychosomatic Medicine. 2000;62(3):326-36.
  3. Kilincalp S, Çoban Ş, Akinci H, Hamamcı M, Karaahmet F, Coşkun Y, et al. Neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and mean platelet volume as potential biomarkers for early detection and monitoring of colorectal adenocarcinoma. European Journal of Cancer Prevention. 2015;24(4):328-33.
  4. Dai Y, Huo X, Cheng Z, Wang Q, Zhang Y, Xu X. Alterations in platelet indices link polycyclic aromatic hydrocarbons toxicity to low-grade inflammation in preschool children. Environment International. 2019;131:105043. Zalsman G, Aslanov-Farbstein D, Rehavi M, Roz N, Vermeiren R, Laor N, et al. Platelet vesicular monoamine transporter 2 density in the disruptive behavior disorders. Journal of Child Adolescent Psychopharmacology. 2011;21(4):341-4.
  5. Metin Ö, Ray PC, Shamkhalova U, Karci CK, Tahiroglu AY, Kaypakli GY. The Relationship between platelet activation markers and anxiety symptoms in ADHD. Klinik Psikofarmakoloji Bulteni. 2018;28:113. Fluegge K, Fluegge K. Environmental factors influencing the link between childhood ADHD and risk of adult coronary artery disease. Medical Hypotheses. 2018;110:83-5.
  6. Ozdemir R, Karadeniz C, Doksoz O, Celegen M, Yozgat Y, Guven B, et al. Are mean platelet volume and platelet distribution width useful parameters in children with acute rheumatic carditis? J Pediatric Cardiology. 2014;35(1):53-6.
  7. Martin J, Trowbridge E, Salmon G, Plumb J. The biological significance of platelet volume: its relationship to bleeding time, platelet thromboxane B2 production and megakaryocyte nuclear DNA concentration. J Thrombosis Research. 1983;32(5):443-60.
  8. Ataoglu A, Canan F. Mean platelet volume in patients with major depression: effect of escitalopram treatment. Journal of Clinical Psychopharmacology. 2009;29(4):368-71.
  9. Canan F, Dikici S, Kutlucan A, Celbek G, Coskun H, Gungor A, et al. Association of mean platelet volume with DSM-IV major depression in a large community-based population: the MELEN study. Journal o