Journals / MN Kardiyoloji / 2004 / Cilt: 11 - Sayı: 4

Value to tissue doppler echocardiographic parameters of diastolic function in the diagnosis of ischemic heart disease: A study in young adult males with typical angina

İskemik kalp hastalığı tanısında diyastolik fonksiyona ait doku doppler ekokardiyografi parametrelerinin değeri: Tipik anginası olan genç erişkin erkeklerde yapılan bir çalışma

Pages
254–259
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: None of the parameters were excellent in discriminating ischemic ones from nonischemic ones, however there are some cut-off values that may promote the using or not using the further more sophisticated tests.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Prevalence of coronary heart disease is progressively increasing.
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Key Findings & Data:Materials and Methods: The study included 66 young adult male patients with typical angina (age=42$\pm$9 years).
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Conclusion & Impact:Conclusion: None of the parameters were excellent in discriminating ischemic ones from nonischemic ones, however there are some cut-off values that may promote the using or not using the further more sophisticated tests.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Erişkin · Koroner hastalık · Ekokardiyografi

Abstract

Aim: Prevalence of coronary heart disease is progressively increasing. Although the history and physical examination is the main part of the examination, importance of adjuvant diagnostic tests is increasing. Tissue Doppler is becoming a routine part of the echo examinations. In this study, we aimed at finding out the role of tissue Doppler echocardiography in diagnosing ischemic heart disease in young adult female patients with typical angina and no wall motion abnormality in echo examination. Materials and Methods: The study included 66 young adult male patients with typical angina (age=42$\pm$9 years). The patients with previously diagnosed other entities that may influence tissue Doppler findings such as diabetes, hypertension, connective tissue disease, obesity and elders were excluded. In addition to the routine parameters, these parameters were also obtained from five consecutive beats: mitral E-peak velocity (E), mitral A peak velocity (A), annular E peak velocity (Em), annular A peak velocity (Am), annular peak systolic velocity (Sm), isovolumetric contraction peak velocity (IVC), isovolumetric relaxation peak velocity (IVR), mitral E/A and annular Em/Am. The diagnosis of ischemic heart disease was established by myocardial perfusion scintigraphy. Results: Only Em and Em/Am was significantly different between ischemic and nonischemic patients (p=0.027 and p=0.023), while E and E/A was at borderline significance (p=0.073 and p=0.055). None of the parameters showed a good ROC analysis result as assessed by area under ROC curve. However ROC curve values at 90% specificity for the diagnosis of ischemic heart disease were as follows: 11 and 19.5 for Em; 0.85 and 1.78 for Em/Am. Between these cut-off values, Em and Em/Am were deemed as nonsignificant. Conclusion: None of the parameters were excellent in discriminating ischemic ones from nonischemic ones, however there are some cut-off values that may promote the using or not using the further more sophisticated tests.

Özet

Amaç: Koroner kalp hastalıklarının prevalansı gün geçtikçe artmaktadır. Her ne kadar anamnez ve fizik muayene tanının temel taşı olsalar da ek tetkikler de önemli bir yere sahiptir. Doku Doppler ekokardiyografi, ekokardiyografik incelemelerin rutin bir parçası haline gelmektedir. Bu çalışmada tipik anginası olan ancak ekokardiyografi incelemesinde duvar hareket bozukluğu olmayan genç erişkin erkek hastalarda ölçülen longitudinal doku Doppler parametrelerinin iskemik kalp hastalığı tanısındaki yeri araştırılmıştır. Gereç ve Yöntem: Çalışmaya 66 genç erişkin erkek hasta alındı (42$\pm$9 yıl). Doku Doppler parametrelerini etkileyebileceği düşünülen diabetes mellitus, hipertansiyon, obesite, bağ doku hastalığı ve ileri yaş hastaları çalışma dışında tutuldu. Rutin parametreler yanında ardışık beş atımdan mitral E (E), mitral E/A, mitral A, anuler E (Em), anuler A (Am), izovolumetrik kontraksiyon dalgası, izovolumetrik relaksasyon dalgası belirlendi. İskemik kalp hastalığı tanısı miyokardiyal perfuzyon sintigrafisi ile kondu. Bulgular: İskemik ve iskemik olmayan grup arasında yalnızca Em ve Em/Am açısından fark vardı (p=0.027 ve p=0.023). Mitral E ve mitral E/A açısından fark sınırda idi (p=0.073 ve p=0.055). ROC (receiver operating characteristics) grafiğine göre hiçbir parametre için iyi biri sınır değeri bulunamadı. Bununla birlikte ROC eğrilerinden iskemik kalp hastalığını dışlamak için ve tanı koymak için %90 spesifisiteye sahip değerler Em için 11 ve 19.5; Em/Am için 0.85 ve 1.78 olarak saptandı. Bu değerler arasında ise bu parametrelerin anlamlı olmadığı sonucuna varıldı. Sonuç: Doku Doppler parametrelerinin hiçbirisi iskemik olguların iskemik olmayanlardan ayırımında yeterli kesinliğe sahip değildi ancak bazı sınır değerleri daha ileri testlerin kullanılıp kullanılmaması konusunda yol gösterici olabilir.

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Cite This Article

UZUN, M., BAYSAN, O., KIRILMAZ, A., SAĞ, C., KÖZ, C., ERİNÇ, K., ÖZKAN, M., KARAEREN, H., GENÇ, C., IŞIK, E. (2004). Value to tissue doppler echocardiographic parameters of diastolic function in the diagnosis of ischemic heart disease: A study in young adult males with typical angina. MN Kardiyoloji, Cilt: 11 - Sayı: 4, 254–259. https://ajindex.com/articles/299200

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