Journals / MN Kardiyoloji / 2006 / Cilt: 13 - Sayı: 1

Effect of blood glucose control on right and left ventricular diastolic functions in diabetic patients

Diabetik hastalarda insülin tedavisinin sağ ve sol ventrikül diyastolik fonksiyonları üzerine etkisi

Pages
15–19
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: It was demonstrated that insulin therapy in the patients of type-II diabetes did not affect left and right ventricle dias­to­lic parameters

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The aim of this study was to investigate whether there are changes in left and right ventricular diastolic func­tions in type-II diabetes after six mounth insulin therapy.
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Key Findings & Data:Materials and Methods: Thirty five consecutive patients with newly diagnosed type-II diabetes were studied by ec­hocardiography, and their fasting glucose and HbA1c were studied before and after 6 months insulin therapy.
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Conclusion & Impact:Conclusion: It was demonstrated that insulin therapy in the patients of type-II diabetes did not affect left and right ventricle dias­to­lic parameters
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kan şekeri · Diabetes mellitus · Diyastol

Abstract

Aim: The aim of this study was to investigate whether there are changes in left and right ventricular diastolic func­tions in type-II diabetes after six mounth insulin therapy. Materials and Methods: Thirty five consecutive patients with newly diagnosed type-II diabetes were studied by ec­hocardiography, and their fasting glucose and HbA1c were studied before and after 6 months insulin therapy. By using Doppler tissue imaging, peak early diastolic (Em), peak late diastolic (Am) and peak sistolic annular (Sm) ve­lo­cities were measured from both left and right ventricles. The Em/Am ratio was determined. Results: Although fasting glucose and HbA1c were significantly different (before therapy (BT)=286.11±150.42, af­ter therapy (AT)=164.97±39.75, p<0.001), blood pressure, heart rate and echocardiographic parameters did not chan­ge after therapy (Sm; BT=9.81±2.09, AT=10.05±2.13, p=0.422, Em; BT=7.81±2.19, AT=8.08±2.01, p=0.328, Am; BT=8.27±2.66, AT=8.77±2.59, p=0.062, Em/Am; BT=0.98±0.21, AT=0.95±0.18, p=0.156). Conclusion: It was demonstrated that insulin therapy in the patients of type-II diabetes did not affect left and right ventricle dias­to­lic parameters

Özet

Amaç: Bu çalışmanın amacı, tip-II diyabetlilerde altı ay insülin tedavisinden sonra sol ve sağ ventrikülün diyastolik fonksiyonlarında değişiklik olup olmadığını araştırmak. Gereç ve Yöntem: Ardışık 35 yeni tanı konulmuş tip-II diyabetik hasta tedavi öncesi ve sonrasında e­ko­kar­di­yog­ra­fiyle çalışıldı ve bu hastaların açlık kan şekeri (AKŞ) ve HbA1c değerleri tedavi öncesi ve sonrasında ölçüldü. Do­ku Doppler görüntüleme kullanılarak zirve erken diyastolik akım (Em ), zirve geç diyastolik akım (Am), zirve sistolik a­kım (Sm) annuler velositeler hem sol hem de sağ ventrikülden ölçüldü. Bulgular: AKŞ ve HbA1c tedavi sonrasında önemli derecede farklı olmasına rağmen (tedavi öncesi (TÖ)=­286.11­±­150.42, te­davi sonrası (TS)=164.97±39.75, p<0,001), ortalama kan basıncı, kalp hızı ve e­ko­kar­di­yog­ra­fik pa­ra­met­relerde (Sm; TÖ=9.81±2.09, TS=10.05±2.13, p=0.422, Em; TÖ=7.81±2.19, TS=8.08±2.01, p=0.328, Am; TÖ=8.27±2.66, TS=8.77±2.59, p=0.062, Em/Am; TÖ=0.98±0.21, TS=0.95±0.18, p=0.156) tedavi sonrasında de­ği­şik­lik gözlenmedi. Sonuç: Tip-II diyabetik hastalarda kan şekeri kontrolünün sağ ve sol ventrikül diyastolik fonksiyonları etkilemediği gös­terildi.

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Cite This Article

GÜR, M., ÖZDOĞRU, İ., İNANÇ, T., KALAY, N., YILMAZ, R., DEMİRBAĞ, R., ÇALIŞKAN, M., GÜL, İ. (2006). Effect of blood glucose control on right and left ventricular diastolic functions in diabetic patients. MN Kardiyoloji, Cilt: 13 - Sayı: 1, 15–19. https://ajindex.com/articles/299187

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