AI Summary & Key Takeaways
AI InsightConclusion: Aortic stiffness and epicardial fat tissue thickness were found to be increased in patients diagnosed with cardiac syndrome X.
📌 3 Key Takeaways
Abstract
Objective: The aim of this study was to investigate the epicardial fat tissue thickness and aortic stiffness in patients with cardiac syndrome X. Material and Method: This prospective study included 85 patients with typical anginal symptoms and a positive exercise stress test or ischemia in myocardial perfusion scintigraphy and normal coronary arteries detected angiographically, and 85 otherwise healthy subjects with a negative stress test for ischemia. Epicardial fat tissue, aortic stiffness index and aortic distensibility were calculated echocardiographically. The results of two groups were compared to each other. Results: Age, gender, and body mass index were similar between the groups. Aortic stiffness index was higher in cardiac syndrome X patients compared to healthy individuals (2.44±0.33 and 3.75±0.53, p<0.001). Also, aortic distensibility was lower in cardiac syndrome X patients than those with control groups (2.98±1.24 and 5.31±2.82, p<0.001). Epicardial fat tissue thickness was significantly higher in the cardiac syndrome X group than in the control group (0.66±0.21 cm and 0.46±0.38 cm respectively, p<0.001). Patients with diagnosis of cardiac syndrome X had significantly higher serum C-reactive protein levels than the control group (p<0.001). Conclusion: Aortic stiffness and epicardial fat tissue thickness were found to be increased in patients diagnosed with cardiac syndrome X.
Özet
Amaç: Bu çalışmanın amacı kardiyak sendrom X olan hastalarda epikardiyal yağ dokusu kalınlığı ve aortik sertliği araştırmaktır. Gereç ve Yöntem: Bu prospektif çalışmaya, tipik anjinal şikayetleri olan ve egzersiz stres testinde veya miyokard perfüzyon sintİgrafisinde iskemisi olan ve anjiyografik olarak normal koroner arterler saptanan 85 hasta ile iskemi açısından negatif stres testi sonucu olan 85 sağlıklı hasta dahil edildi. Ekokardiyografik olarak epikardiyal yağ dokusu, aortik sertlik indeksi ve aortik distensibilite hesaplandı. İki grubun sonuçları karşılaştırıldı. Bulgular: Her iki grupta da yaş, cinsiyet ve vücut kÜtle indeksi benzerdi. Aortik sertlik indeksi sağlıklı bireylere göre kardiyak sendrom X’i olan hastalarda daha yüksekti (2,44±0,33 ve 3,75±0,53 p<0,001). Aortik distenbilite ise kardiyak sendrom X grubunda kontrol grubuna göre daha düşüktü (2,98±1,24 ve 5,31±2,82 p<0,001). Epikardiyal yağ dokusu kalınlığı kardiyak sendrom X grubunda kontrol grubuna göre daha düşüktü (0,66±0,21 cm ve 0,46±0,38 cm p<0,001). Kardiyak sendrom X tanısı olan hastalar, kontrol grubuna göre daha yüksek serum C-reaktif protein değerlerine sahipti (p<0,001). Sonuç: Kardiyak sendrom X tanısı olan hastalarda aortik sertliğin ve epikardiyal yağ dokusu kalınlığının arttığı bulunmuştur