Journals / Retina-Vitreus / 2020 / Cilt: 29 - Sayı: 3

Effectiveness of Ranibizumab and Afl ibercept in Branch Retinal Vein Occlusion

Pages
232–237
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: In our study, no signifi cant difference was detected in reduction of central foveal thickness, improvement in visual acuity and number of injections between two agents.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: To assess functional and anatomic effectiveness of intravitreal ranibizumab and afl ibercept injection given to patients with macular edema secondary to branch retinal vein occlusion.
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Key Findings & Data:Method: We retrospectively reviewed fi les of 62 treatment-naive patients with macular edema due to branch retinal vein occlusion.
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Conclusion & Impact:Conclusion: In our study, no signifi cant difference was detected in reduction of central foveal thickness, improvement in visual acuity and number of injections between two agents.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Purpose: To assess functional and anatomic effectiveness of intravitreal ranibizumab and afl ibercept injection given to patients with macular edema secondary to branch retinal vein occlusion. Method: We retrospectively reviewed fi les of 62 treatment-naive patients with macular edema due to branch retinal vein occlusion. The best-corrected visual acuity and optic coherence parameters were recorded on months 0, 1, 3, 6 and 12 in all patients. First 3 injections were performed in a monthly manner. Pro re nata (PRN) regimen was given during follow-up. Findings: Baseline visual acuity was 50.7±7.6 letters in ranibizumab group and 49.2±6.7 letters in afl ibercept group (p=0.403). No signifi cant difference was detected in visual acuity on month 12 between groups (p=0.313). Again, no signifi cant difference was detected in central foveal thickness on month 12 between groups (p=0.408). Mean number of intravitreal injection was 6.2±1.4 in ranibizumab group and 5.7±1.0 in afl ibercept group (p=0.174). At the end of month 12, complete recovery in subretinal detachment was detected in 16 patients (88.8%) receiving ranibizumab and 15 patients receiving afl ibercept (93.8%) (p=0.525). Conclusion: In our study, no signifi cant difference was detected in reduction of central foveal thickness, improvement in visual acuity and number of injections between two agents.

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Cite This Article

KABATAŞ, N., BİÇER, T., ÇALIŞKAN, S., ÇELİKAY, O., GÜRDAL, C. (2020). Effectiveness of Ranibizumab and Afl ibercept in Branch Retinal Vein Occlusion. Retina-Vitreus, Cilt: 29 - Sayı: 3, 232–237. https://ajindex.com/articles/298732

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