The relationship between coronary artery disease and Chlamydia pneumoniae infection

CONCLUSION: In this study CP positivity didn't show any difference between the control group and coronary angiographically proven CAD group which suggested that CP infection was not an independent risk factor for CAD.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: To investigate Chlamydia pneumoniae (CP) as a risk factor for coronary artery disease (CAD).

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Key Findings & Data:METHOD: In this study 90 patients who had undergone coronary angiography with initial diagnosis of CAD were investigated.

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Conclusion & Impact:CONCLUSION: In this study CP positivity didn't show any difference between the control group and coronary angiographically proven CAD group which suggested that CP infection was not an independent risk factor for CAD.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Chlamydia pneumoniae · Koroner anjiyografi · Risk faktörleri

Abstract

AIM: To investigate Chlamydia pneumoniae (CP) as a risk factor for coronary artery disease (CAD). METHOD: In this study 90 patients who had undergone coronary angiography with initial diagnosis of CAD were investigated. Just before left ventriculography, ventricle blood was taken from the patients and the relationship between CAD and CP seroactivity (IgG, IgM and IgA) was examined. For this reason the patients were separated into 3 groups who have 1, 2 and 3 vessel lesions and the results were compared with the group who have normal coronary angiography. RESULTS: 21 patients had I vessel, 23 had 2 vessel and 24 had 3 vessel disease. The control group consisted of 22 people. When the group with normal coronary arteries were compared with the groups of 1, 2 and 3 vessel .lesions, no statistically meaningful difference was obtained considering CP, IgG, IgM and IgA antibody response (p>0.05). CONCLUSION: In this study CP positivity didn't show any difference between the control group and coronary angiographically proven CAD group which suggested that CP infection was not an independent risk factor for CAD.

Özet

AMAÇ: Chlamydia pneumoniae (CP) 'nin koroner arter hastalığı (KAH) için bir risk faktörü olup olmadığını araştırmak. YÖNTEM: Çalışmaya KAH ön tanısı ile başvurup, koroner anjiografileri yapılan 90 hasta alındı. Hastalardan sol ventrikülografı yapılmadan hemen önce ventrikül kanı alınarak, CP seroaktivitesi (IgG, IgM ve IgA) ile KAH arasındaki ilişki incelendi. Bu amaçla olgular l damar. 2 damar ve 3 damar lezyonu olan hastalar olmak üzere üç gruba ayrılarak, koroner anjiografisi normal olan grupla karşılaştırıldı. BULGULAR: Olguların 21 'inde l damar, 23'ünde 2 damar ve 24'ünde 3 damar lezyonu vardı. Kontrol grubu ise 22 kişi idi. Koroner arterleri normal olan.grupla l damar, 2 damar ve 3 damar lezyonu olan gruplar karşılaştırıldığında CP IgG, IgM ve IgA antikor cevabı bakımından istatistiki olarak anlamlı bir farklılık bulunamadı (p>0,05). SONUÇ: Bu çalışmada, koroner anjiografi ile KAH tesbit edilen hastalarda CP.pozitifliği kontrol grubundan farklı bulunmadı. Bu da bize CP enfeksiyonunun KAH için bağımsız bir risk faktörü olmadığını düşündürdü.

Keywords

Chlamydia pneumoniae Koroner anjiyografi Risk faktörleri Chlamydia enfeksiyonları Koroner hastalık Coronary Angiography Risk Factors Chlamydia Infections Coronary Disease

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Cite This Article

BAYKAN, M., ÇELİK, Ş., GÖKÇE, M., KARAHAN, B., ÖREM, C., CİHANYURDU, M., AYDIN, F., CANYILMAZ, D., ERDÖL, C. (2000). The relationship between coronary artery disease and Chlamydia pneumoniae infection. MN Kardiyoloji, Cilt: 7 - Sayı: 1, 11–13. https://ajindex.com/articles/298076

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