Journals / MN Kardiyoloji / 2003 / Cilt: 10 - Sayı: 6

Right ventricular long-axis functions in patients with untreated essential hypertension: Tissue Doppler study

Tedavisiz esansiyel hipertansiyonlu hastalarda sağ ventrikül uzun aks fonksiyonları: Doku Doppler çalışması

Pages
441–446
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The results of this study indicated that right ventricular long-axis myocardial systolic and diastolic functions measured by TDI deteriorated in patients with untreated essential hypertension.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: We aimed to investigate right ventricular long-axis functions by tissue Doppler imaging (TDI) in patients with untreated essential hypertension in this study.
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Key Findings & Data:Material and Methods: 36 patients with untreated essential hypertension and 20 normotensive healthy subjects were included in this study.
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Conclusion & Impact:Conclusion: The results of this study indicated that right ventricular long-axis myocardial systolic and diastolic functions measured by TDI deteriorated in patients with untreated essential hypertension.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hipertansiyon · Ventriküler fonksiyon · sağ

Abstract

Aim: We aimed to investigate right ventricular long-axis functions by tissue Doppler imaging (TDI) in patients with untreated essential hypertension in this study. Material and Methods: 36 patients with untreated essential hypertension and 20 normotensive healthy subjects were included in this study. From the echocardiographic apical 4-chamber views, peak systolic (S), peak early (E) and late diastolic (A) velocities and deceleration time of early diastolic velocity (DT) of the tricuspid annulus at the RV free wall were recorded by tissue Doppler imaging technique. In addition, the tricuspid annulus isovolumic relaxation time (IVRT, from the end of S wave velocity to the beginning of E) was measured. Results: There was no difference between two groups in terms of age. Left ventricular mass index (175.9±5.0 g/m2 vs 104.1±6.3 g/m2 p<0.001), mean blood pressure (139.4±19.6 mmHg vs 91.3±6.6 mmHg p<0.001) and right ventricular anterior wall thickness (4.70±0.33 mm vs 3.49±0.30 mm) were greater in hypertensive patients than in controls. Significant changes in right ventricular longitudinal motion were present in hypertensive patients. In diastole, the E/A ratio was significantly reduced. Relaxation time was negatively correlated with right ventricular anterior wall thickness. In systole, the peak tricuspid annulus S-wave velocity was reduced in hypertensive patients and correlated with right ventricular anterior wall thickness. There was significant correlation between left ventricular mass index and right ventricular anterior wall thickness. In addition to these, there were also similar correlations between left ventricular mitral annulus and tricuspid annulus parameters. Right ventricular anterior wall thickn ess (p<0.001) and diastolic blood pressure (p<0.005) were found to be independent predictors of the tricuspid annulus S wave velocity shortening in multiple regression analysis taken as independent variables systolic blood pressure, diastolic blood pressure, right ventricular anterior wall thickness, left ventricular mass index and age. Conclusion: The results of this study indicated that right ventricular long-axis myocardial systolic and diastolic functions measured by TDI deteriorated in patients with untreated essential hypertension.

Özet

Amaç: Bu çalışmada doku Doppler yöntemi kullanarak tedavisiz esansiyel hipertansiyonlu hastalarda sağ ventrikül uzun aks fonksiyonlarını araştırmayı amaçladık. Gereç ve Yöntem: 36 tedavisiz esansiyel hipertansiyonlu hasta ve 20 normotansif sağlıklı olgu bu çalışmaya alındı. Apikal 4-boşluk yaklaşımdan doku Doppler görüntüleme tekniğinin kullanımı ile sağ ventrikül serbest duvarında trikuspid anulus pik sistolik (S), pik erken (E) ve geç diyastolik (A) akım hızları, erken diyastolik hızın deselerasyon zamanı (DZ) kaydedildi. İlave olarak trikuspid anulus izovolümik relaksasyon zamanı (İVRZ: S dalga velositesinin sonundan E dalgasının başlangıcına kadar) ölçüldü. Bulgular: Her iki grup arasında yaş açısından farklılık yoktu. Sol ventrikül kitle indeksi (175.9±5.0 g/m2 vs 104.1±6.3 g/m2 p<0.001), ortalama kan basıncı (139.4±19.6 mmHg vs 91.3±6.6 mmHg p<0.001) ve sağ ventrikül ön duvar kalınlığı (4.70±0.33 mm vs 3.49±0.30 mm) hipertansiyonlu hastalarda kontrollerden önemli derecede fazla idi. Hipertansif hastalarda sağ ventrikül uzun aks hareketlerinde önemli değişiklikler mevcuttu. Diyastolde E/A oranı belirgin derecede azdı. Relaksasyon zamanı sağ ventrikül ön duvar kalınlığı ile negatif olarak ilişkiliydi. Sistolde trikuspid anulus zirve S dalga hızı hipertansif olgularda azdı ve sağ ventrikül ön duvar kalınlığı ile arasında anlamlı derecede negatif ilişki bulundu. Sol ventrikül kitle indeksi ile sağ ventrikül ön duvar kalınlığı arasında anlamlı ilişki olduğu saptandı. Bunlara ilaveten benzer ilişkiler sol ventrikül mitral anulus ve trikuspid anulus parametreleri arasında da mevcuttu. Yaş, sol ventrikül kas kitle indeksi, sistolik kan basıncı, diyas tolik kan basıncı ve sağ ventrikül ön duvar kalınlığının bağımsız değişken olarak alındığı multipl regresyon analizinde; trikuspid anulus S dalgasının bağımsız belirleyicileri olarak sağ ventrikül ön duvar kalınlığı (p<0.001) ve diyastolik kan basıncı (p<0.005) bulundu. Sonuç: Bu çalışmanın sonuçları tedavisiz esansiyel hipertansiyonlu hastalarda sağ ventrikül uzun aks sistolik ve diyastolik fonksiyonlarının bozulduğunu göstermektedir.

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Cite This Article

YILMAZ, M., AÇIKEL, M., GÜRLERTOP, Y., EROL, M. K., BOZKURT, E., GÜNDOĞDU, F., KARAKELLEOĞLU, Ş. (2003). Right ventricular long-axis functions in patients with untreated essential hypertension: Tissue Doppler study. MN Kardiyoloji, Cilt: 10 - Sayı: 6, 441–446. https://ajindex.com/articles/298021

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