Journals / MN Kardiyoloji / 2000 / Cilt: 7 - Sayı: 4

The relation between free fatty acid levels and arrhythmia in the course of acute myocardial infarction

Akut myokard infarktüsü seyri sırasında serbest yağ asidi düzeyleri ile aritmi arasındaki ilişki

Pages
299–303
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

From this we can conclude that high FFA levels might play a role in developing arrhytmia.

📌 3 Key Takeaways

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Objective & Hypothesis:Acute myocardial infarction (AMI) is still one of the most common causes of death in the world.
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Key Findings & Data:METHODS: FFA levels were measured in 40 patients who were admitted to our clinic with AMI.
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Conclusion & Impact:From this we can conclude that high FFA levels might play a role in developing arrhytmia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Yağ asitleri · esterleşmemiş · Akut hastalık

Abstract

Acute myocardial infarction (AMI) is still one of the most common causes of death in the world. In AMI-related deaths rhythm problems commonly occur in the first hours. AIM: Among the metabolic events following infarction, rising levels of free fatty acids (FFA) deserve attention. In some studies it has been reported that high levels of FFA may cause arrhythmia. For this reason, in our study FFA levels were measured in patients who had AMI, and the effect of FFA levels on AMI and arrhythmia were investigated. METHODS: FFA levels were measured in 40 patients who were admitted to our clinic with AMI. The results of these measurements were compared against a control group (n=25). The FFA levels for AMI patients were studied in two separate groups: those who developed arrhythmias after having AMI (n=l4), and those who did not develop arrhythmias (n=26). The FFA levels were then compared between the two groups. RESULTS: When the FFA levels were compared between the control group (0.302 ± 0.10) and the AMI group (1.362 ± 0.56), a significant difference was observed. When the FFA levels were compared between the group which developed arrhythmias after AMI (1.56 ± 0.37), and the group which did not develop arrhythmias after AMI (1.2 ±0.63) the FFA levels in those who had developed arrhythmia was significantly higher. CONCLUSION: We observered that in AMI patients FFA levels were higher. If we look at the AMI groups, FFA levels were significantly higher in the arrhytmia and AMI group than in the AMI and nonarrhytmia group. From this we can conclude that high FFA levels might play a role in developing arrhytmia.

Özet

Akut miyokard İnfarktüsü (AMI) halen en sık ölüm nedenlerinden biri olmaya devam etmektedir. AMI'ne bağlı ölümlerin en başta geleni ise ilk saatlerde ortaya çıkan ritim problemleridir. AMAÇ: İnfarktüsü takiben gelişen metabolik olaylar zinciri içerisinde, serbest yağ asidi (SYA) düzeylerinin yükselişi dikkati çekmektedir. Bazı çalışmalarda, yüksek SYA düzeylerinin aritmi sebebi olabileceği bildirilmiştir. Bu nedenle, çalışmamızda, AMI geçiren olgularda kan SYA düzeyleri ölçülmüş ve bunun AMI da aritmi üzerine olan etkisi araştırılmıştır. YÖNTEM: Kliniğimize AMI ile başvuran 40 hastada SYA düzeyleri ölçüldü. Bu ölçüm sonuçları kontrol grubu (s=25) ile karşılaştırıldı. AMI geçiren olgulardaki SYA düzeyleri, AMI geçirip de aritmisi olan (s=14) ve olmayan grup (s=26) olarak iki ayrı bölümde incelendi ve her iki gruptaki SYA düzeyleri karşılaştırıldı. BULGULAR: SYA düzeyleri, kontrol gurubu (0.302 ± 0.10) ile, AMI gurubunda (1.362 ± 0.56) karşılaştırıldığında AMI olgularda kontrol grubuna göre anlamlı farklılık gözlendi. AMI geçiren olguların SYA düzeyleri aritmi gelişen ve gelişmeyen grup ile karşılaştırıldığında, aritmi gelişen AMI vakalarında ölçülen SYA değerlerinin (l.56 ± 0.37mmol/L), aritmi geçirmeyen AMI grubuna (1.2 ± 0.63) göre SYA anlamlı olarak yüksek olduğu gözlendi. SONUÇ: AMI geçiren olgularda SYA düzeylerinin yükseldiği gözlenmiştir. AMI olguları kendi içlerinde incelendiğinde aritmi gelişen grupta anlamlı derece yüksek SYA düzeyleri, yüksek SYA düzeylerinin aritmi gelişiminde rol oynayabileceğini düşündürmüştür.

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Cite This Article

ERDOĞDU, S., TUNCEL, P., CANKURTARAN, C., SOYSAL, D., Arı, H. (2000). The relation between free fatty acid levels and arrhythmia in the course of acute myocardial infarction. MN Kardiyoloji, Cilt: 7 - Sayı: 4, 299–303. https://ajindex.com/articles/297849

References (1)

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