SavedAdd your journal

Journals / MN Kardiyoloji / 2000 / Cilt: 7 - Sayı: 4

Morphological characteristics of in-stent restenosis in diabetes mellitus

Diabetes mellitusta stent içi restenozların morfolojik özellikleri

Ahmet ALPMAN
Pages
281–285
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

CONCLUSION: Restenosis patterns did not differ between the patients with and without diabetes mellitus.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:AIM: Restenosis remains a major limitation to percutaneous revascularization.
📊
Key Findings & Data:MATERIAL AND METHODS: Between November 1997 and December 1998, 285 patients underwent coronary stenting and control angiography.
💡
Conclusion & Impact:CONCLUSION: Restenosis patterns did not differ between the patients with and without diabetes mellitus.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Diabetes mellitus · Koroner restenoz · Stentler

Abstract

AIM: Restenosis remains a major limitation to percutaneous revascularization. Stents reduce angiographic restenosis in comparison with balloon angioplasty. Patients with diabetes mellitus have a greater incidence of restenosis. The purpose of the present study is to compare restenosis patterns of patients with and those without diabetes. MATERIAL AND METHODS: Between November 1997 and December 1998, 285 patients underwent coronary stenting and control angiography. Eighty five were diabetic. In-stent restenosis rate was significantly higher in diabetic than nondiabetic patients (51.8% vs 26.5%, p=0.0002). We evaluated angiographic classification of in-stent restenosis. according to the geographic distribution of intimal hyperplasia in reference to implanted stent. Patterns include focal, diffuse and total occlusion. The stent size and length were similar between groups. There was no observed difference in the vessel treated and stent types in both groups. CONCLUSION: Restenosis patterns did not differ between the patients with and without diabetes mellitus.

Özet

AMAÇ: Restenoz, perkutan revaskülarizasyon girişimlerinin en büyük problemlerinden birisidir. Balon anjiyoplasti ile kıyaslandığında stentler restenozu azaltmaktadır. Ancak diabetes mellitusta restenoz çok daha fazla olmaktadır. Bu çalışma ile diabetes mellitus olan ve olmayan hastalardaki restenoz tipleri karşılaştırılmıştır. GEREÇ VE YÖNTEM: Kasım 1997 ile Aralık 1998 tarihleri arasında stent konulup kontrol koroner anjiografisi yapılan toplam 285 hasta incelendi. Bu hastaların 85 'inde diabetes mellitus vardı. Diabetik hastalardaki stent içi restenoz oranı çok daha yüksek bulundu (%51.8 ve %26.5, p=0.0002). İmplante edilen stentteki intimal hiperplazinin lokalizasyonuna göre stent içi restenozlar; fokal, diffüz ve total olarak sınıflandırıldı. Kullanılan stent çapı ve uzunluğu, gruplar arasında benzerdi. Yine, her iki grup arasında stentin konulduğu arter ve stent tipleri arasında da farklılık yoktu. SONUÇ: Diabetes mellitus olan ve olmayan hastalardaki restenoz tipleri arasında anlamlı farklılık bulunmadı.

🔖

Cite This Article

ALPMAN, A. (2000). Morphological characteristics of in-stent restenosis in diabetes mellitus. MN Kardiyoloji, Cilt: 7 - Sayı: 4, 281–285. https://ajindex.com/articles/297847

References (7)

  1. Kannel WB, McGee DL. Diabetes and cardivascular disease: the Framingham study. JAMA 1979;241:2035-2038.
  2. Hamby Rl, Sherman L, Mehta J, Aintablian A. Repraisal of the role of diabetic state in coronary artery disease. Chest 1976;70:241-247.
  3. Dortimer AC, Shenoy PN, Shiroff RA, et al. Diffuse coronary artery disease in diabetic patients: fact or fiction? Circulation 1978:57; 133- 136. Krolewski AS,. Kozinski EJ, Warram JH, et al. Magnitude and determinants of coronary artery disease in juvenile onset, insulin- dependent diabetes mellitus. Am J Cardiol 1987;59:750-755.
  4. Stamler J, Vaccaro O, Neaton JD, Wenworth D, for the Multiple risk factor interventional trial research group. Diabetes, other risk factors and 12 year cardiovascular mortality for men screened in the multiple risk faktör interventional trial. Diabetes Care 1993; 16:434- 444. Barzilay Jl, Kronmal RA, Bittner V, Eaker E, Evans C, Foster ED. Coronary artery disease and coronary artery bypass grafting in diabetic patients aged > 65 years: report from the coronary artery surgery study (CASS) registry! Am J Cardiol 1994;74:334-339.
  5. Lawrie GM, Morris GC, Glaeser DH. Influence of diabetes mellitus on the results of coronary bypass surgery. JAMA 1986;21:2967- 2971. Morris JJ, Smith LR, Jones RH, et al. Influence of diabetes and mammary artery grafting on survival after coronary bypass. Circulation 1991;84 (suppl 3)III275-III283. Stein B, Weintraub WS, Gebhart S, et al. Influence of diabetes mellitus on early and late outcome after percutaneous transluminal coronary angioplasty. Circulation 1995;91:979-989.
  6. Kip KE, Faxon DP, Detre KM, for the Investigators of the NHLBI PTCA registry. Coronary angioplasty in diabetic patients: the National Heart, Lung, and Blood Institute Percutaneous Transluminal Coronary Angioplasty Registry. Circulation 1996;94:1818-1825.
  7. Savage MP, Fischman DL, Slota P, et al. Coronary intervention in the diabetic patients: improved outcome following stent implantation versus balloon angioplasty. J Am Coll Cardiol 1997;29(Suppl A):188A. Van B, Bauters C, Hubert KL, et al. Restenosis rates in diabetic patients: a comparison of coronary stenting and balloon angioplasty in native coronary arteries. Circulation 1997;96:1454-1460. The Bypass Angioplasty Revascularization Investigation (BARI) Investigators. Comparison of coronary bypass surgery with, angioplasty in patients with multivessel disease. N Engl J Med 1996;335:217-225. Serruys PW, de Jaegere P, Kiemenei F, for the Benestent Study