Aortic root function in patients with rheumatoid arthritis

Objective & Hypothesis:AIM: To investigate the aortic root function in patients with rheumatoid arthritis, a chronic multisystemic disease that can be complicated by aortitis.

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Key Findings & Data:MATERIAL AND METHODS: 29 patients with RA and 29 healthy subjects were included in the study.

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Conclusion & Impact:This may be due to aortitis and may affect cardiac function in patients with RA at long term.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Aort · Artrit · romatoid

Abstract

AIM: To investigate the aortic root function in patients with rheumatoid arthritis, a chronic multisystemic disease that can be complicated by aortitis. MATERIAL AND METHODS: 29 patients with RA and 29 healthy subjects were included in the study. In addition to the standard echocardiographic examination, aortic root function was evaluated in these groups by transthoracic M-mode echocardiography. RA was diagnosed according to the ARA criteria of 1987. Blood pressure with end-systolic (AoS) and end-diastolic (AoD) M-mode measurements of ascending aorta were used to calculate the indices of aortic root function: beta index (Peterson's elastic modulus), cross-sectional aortic compliance, aortic stiffness index and aortic root distensibility. RESULTS: AoS and AoD were significantly higher in patients with RA than the control group (p<0.05). Aortic stiffness and beta indexes were significantly higher in RA group when compared with the controls. On the other hand, there were no significant differences in cross-sectional aortic compliance and aortic root distensibility between the two groups (p>0.05). CONCLUSION: When compared with the healthy subjects AoS, AoD, beta index and aortic stiffness index are significantly higher in patients with RA. This may be due to aortitis and may affect cardiac function in patients with RA at long term.

Özet

AMAÇ: Bu çalışmanın amacı kronik bir multisistemik hastalık olan ve birlikte aortit görülebilen romatoid artritte (RA) aort kökü fonksiyonunu araştırmak idi. GEREÇ VE YÖNTEM: RA'li 29 hasta ve benzer yaşlardan 29 sağlıklı bireyi standart ekokardiyografik incelemeye ek olarak aort kökü fonksiyonları açısından transtorasik M-mode ekokardiyografi ile değerlendirdik. RA tanısı 1987 ARA kriterlerine göre kondu. Kan basıncı ölçümleri ve M-mode ile alınan sistol-sonu (AoS) ve diyastol-sonu (AoD) aort çapı ölçümlerinden beta indeksi (Peterson'un elastik modülü), kesitsel aort kompliyansı, aort sertlik indeksi ve aort kökü distensibilitesi hesaplandı. BULGULAR: AoS ile AoD RA grubunda kontrol grubuna göre anla mlı derecede yüksek idi (p<0.05). Beta ve aort sertlik indeksi, RA grubunda kontrol grubuna göre anlamlı derecede yüksek iken (p<0.05), KAK ve AKD açısından her iki grup arasında anlamlı bir fark bulunamadı. SONUÇ: RA hastalarında AoS, AoD, beta indeksi ve aort sertlik indeksi sağlıklı bireylerden daha yüksektir. Bu durum RA'de daha önce bildirilmiş olan aortite bağlı olabilir ve uzun dönemde RA hastalarında kalp fonksiyonlarını etkileyebilir

Keywords

Aort Artrit romatoid Kan basıncı tayini Tanı teknikleri kalp damar Ekokardiyografi Aorta Arthritis Rheumatoid Blood Pressure Determination Diagnostic Techniques Cardiovascular Echocardiography

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Cite This Article

ALPASLAN, M., EVCİK, D., ONRAT, E. (2001). Aortic root function in patients with rheumatoid arthritis. MN Kardiyoloji, Cilt: 8 - Sayı: 2, 102–105. https://ajindex.com/articles/297733

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