Journals / MN Kardiyoloji / 2010 / Cilt: 17 - Sayı: 1

When should we reinitiate anticoagulant therapy in patients with prosthetic heart valves and who suffer from major bleeding? a review of the literature

Majör kanaması olan protez kapaklı hastada yeniden antikoagülasyona ne zaman başlanmalı? olgular eşliğinde literatürde gözden geçirme

Pages
67–71
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The aim of this study is to go over the available studies in the literature and to provide the clinicians with an approach about this group of patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Usage of long term anticoagulant accompanies bleeding episodes.
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Key Findings & Data:Bleeding rates change according to the accompanying disorders and age of the patient.
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Conclusion & Impact:The aim of this study is to go over the available studies in the literature and to provide the clinicians with an approach about this group of patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Usage of long term anticoagulant accompanies bleeding episodes. Bleeding rates change according to the accompanying disorders and age of the patient. Our knowledge related to how and when anticoagulation should be started in patients using warfarin due to mechanic heart valves or other serious risk factors is limited to the case reports and serials because of absence of randomized controlled studies in the literature. The aim of this study is to go over the available studies in the literature and to provide the clinicians with an approach about this group of patients.

Özet

Uzun dönem antikoagülan tedavi kullanımı, kanama epizotları ile birliktelik gösterir. Kanama oranları, hastanın eşlik eden hastalıkları ve yaşına bağlı olarak değişmektedir. Mekanik kalp kapakları veya diğer risk faktörleri nedeniyle warfarin kullanan hastalarda majör kanama epizotları sonrasında tekrar antikoagülasyona nasıl ve ne zaman başlanması gerektiği konusunda bilgimiz, mevcut literatürde randomize kontrollü çalışma olmaması sebebiyle olgu raporları ve olgu serileri ile sınırlıdır. Bu yayının amacı literatürdeki mevcut yayınların gözden geçirilmesi ve böylelikle bu hasta grubuna yaklaşım için klinisyenlerde bir fikir oluşturmaktır.

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Cite This Article

YONTAR, O. C., TANDOĞAN, İ. (2010). When should we reinitiate anticoagulant therapy in patients with prosthetic heart valves and who suffer from major bleeding? a review of the literature. MN Kardiyoloji, Cilt: 17 - Sayı: 1, 67–71. https://ajindex.com/articles/297472

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References (4)

  1. Hylek EM, Singer DE. Risk factors for intracranial hemorrhage in outpatients taking warfarin. Ann Intern Med 1994; 120: 897–902
  2. Stein PD, Grandison D, Hua TA et al. Therapeutic levels of oral anticoagulation with warfarin in patients with mechanical prosthetic heart valves: review of literature and recommendations based on international normalized ratio. Postgrad Med J 1994; 70(suppl 1):S72-S83 3. Cannegieter SC, Rosendaal FR, Wintzen AR, van der Meer FJ, Vandenbroucke JP, Briët E. Optimal oral anticoagulant therapy in patients with mechanical heart valves. N Engl J Med 1995; 333:11-17 4. Cannageiter SC, Rosendaal FR, Briet E. Thromboembolic and bleeding complications in patients with mechanical prosthetic heart valve prostheses. Circulation 1994; 89:635-41 5. Gomez CR, Sandhu J, Mehta P. Resumption of anticoagulation during hypertensive cerebral hemorrhage with prosthetic heart valve [letter]. Stroke 1988;19:407 6. Babikian VL, Kase CS, Pessin MS, Caplan LR, Gorelick PB. Resumption of anticoagulation after intracranial bleeding in patients with prosthetic heart valves. Stroke 1988; 19:407-8 7. Kawamata T, Takeshita M, Kubo O, Izawa M, Kagawa M, Takakura K. Management of intracranial hemorrhage associated with anticoagulant therapy. Surg Neurol 1995; 44:438-43 8. Nagano N, Tabata H, Hashimoto K. Anticoagulant related intracerebral hemorrhage in patients with prosthetic heart valves: report of two patients. Neurol Med Chir (Tokyo) 1991; 31:743-5 9. Peyman MA. The significance of hemorrhage during treatment of patients with coumadin anticoagulants. Acta Med Scand 1958; 162 (suppl):1-62 10. Lau CP, Chang CM, Lau GKK, Wong CK, Fong PC, Yu YL. Cerebral hemorrhage in anticoagulated patients with nonseptic mechanical valvular prothesis. International Journal of Cardiology 1991; 30:289-96 11. Butler AC, Tait RC. Restarting anticoagulation in prosthetic heart valve patients after hemorrhage: a 2-year follow-up. British Journal of Haemotolgy. 1998; 103, 1064-6 12.,Leker RR, Abramsky O. Early anticoagulation in patients with prosthetic heart valves and intracerebral hema - toma. Neurology 1998;50:1489-91
  3. Wijdicks EF, Schievink WI, Brown RD, Mullany CY. Early anticoagulation in patients with prosthetic heart valves and intracerebral hematoma. Neurology. 1999; 52:676-7
  4. Wijdicks EF, Schievink WI, Brown RD, Mullany CY. The dilemma of discontinuation of anticoagulation therapy for patients with intracranial hemorrhage and mechanical heart valves. Neuros