Journals / MN Kardiyoloji / 2010 / Cilt: 17 - Sayı: 3

The comparison of mean platelet volume in patients with normal coronary arteries with and without hypertension

Hipertansiyonu olan ve olmayan koroner arterleri normal hastalarda ortalama trombosit hacminin karşılaştırılması

Pages
155–159
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: MPV value alone remains inadequate in showing the presence of platelet activation in patients with hypertension not having coronary artery disease

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Hypertension (HT) is an important risk factor known for vascular diseases.
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Key Findings & Data:Material and Method: 80 patients having angiographically proven normal coronary arteries were included in the study.
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Conclusion & Impact:Conclusion: MPV value alone remains inadequate in showing the presence of platelet activation in patients with hypertension not having coronary artery disease
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Hypertension (HT) is an important risk factor known for vascular diseases. The presence of platelet activation in hypertension is well known. Mean platelet volume (MPV) is an indicator of platelet activation. In this study, we aimed to compare MPV in patients with or without HT all having angiographically proven normal coronary arteries, in order to confirm the presence of platelet activation in HT. Material and Method: 80 patients having angiographically proven normal coronary arteries were included in the study. The patients were classified into two groups according to the presence of HT, as the hypertensive group (HTG, n=40) and the non-hypertensive group (NHTG, n=40). MPV values were obtained from all patients. Results: No significant difference was found between the groups in terms of age, gender and other demographic characteristics (p>0.05). Both groups were also compared in terms of MPV value and no statistically significant difference was detected between the groups (8.21 ± 0.63 to 8:17 ± 0.69 fl, respectively; p = 0.81). Conclusion: MPV value alone remains inadequate in showing the presence of platelet activation in patients with hypertension not having coronary artery disease

Özet

Hipertansiyon (HT) vasküler hastalıklar için bilinen önemli bir risk faktörüdür. HT’da trombosit aktivasyonunun varlığı iyi bilinmektedir. Ortalama trombosit hacmi (OTH) trombosit aktivasyonunun bir göstergesidir. Biz bu çalışmada, HT’u olan hastalarda trombosit aktivasyonunun varlığını desteklemek için anjiyografik olarak koroner arterleri normal HT’u olan ve olmayan hasta gruplarında OTH’ ni kıyaslamayı amaçladık. Gereç ve Yöntem: Çalışmaya anjiyografik olarak kanıtlanmış normal koroner arterleri olan 80 hasta alındı. Bu hastalar HT’u olan (n=40) ve olmayan (n=40) şeklinde iki gruba ayrıldı. Tüm hastaların OTH değerleri ölçüldü. Bulgular: Her iki grup arasında yaş, cinsiyet ve diğer demografik özellikler açısından fark saptanmadı (p>0,05). Ayrıca her iki grup OTH değeri açısından kıyaslandığında gruplar arasında istatistiksel olarak fark saptanmadı (8,21± 0,63 karşın 8,17±0,69 fl, sırasıyla; p=0,81). Sonuç: Koroner arter hastalığı gelişmemiş HT hastalarında sadece OTH değeri trombosit aktivasyonun varlığını göstermede yetersiz gibi gözükmektedir.

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Cite This Article

AÇIKGÖZ, N., ERMİŞ, N., YAĞMUR, J., ÇUĞLAN, B., ATAŞ, H., ÖZDEMİR, R. (2010). The comparison of mean platelet volume in patients with normal coronary arteries with and without hypertension. MN Kardiyoloji, Cilt: 17 - Sayı: 3, 155–159. https://ajindex.com/articles/297424

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