Journals / MN Kardiyoloji / 2018 / Cilt: 25 - Sayı: 2

The Association Between Serum Procalcitonin Levels and Selvester QRS Score in ST Elevation Myocardial Infarction Patients

ST Segment Yükselmeli Miyokard Enfarktüsü Hastalarında Serum Prokalsitonin Düzeyleri ve Selvester QRS Skoru Arasındaki İlişki

Pages
52–59
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Procalcitonin is a promising, simple biomarker with a similar accuracy to the Selvester QRS score in predicting the extent of infarct size.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The value of Selvester score have been documented by previous studies in predicting prognosis ST elevation myocardial infarction.
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Key Findings & Data:Material and Method: This was a cross-sectional, observational clinical study involving 873 consecutive ST elevation myocardial infarction patients.
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Conclusion & Impact:Conclusion: Procalcitonin is a promising, simple biomarker with a similar accuracy to the Selvester QRS score in predicting the extent of infarct size.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The value of Selvester score have been documented by previous studies in predicting prognosis ST elevation myocardial infarction. Higher procalcitonin levels were reported as a novel marker with prognostic value in STEMI. To evaluate the relationship between serum procalcitonin level and the Selvester score in ST elevation myocardial infarction population. Material and Method: This was a cross-sectional, observational clinical study involving 873 consecutive ST elevation myocardial infarction patients. After exclusion, biochemical parameters, complete blood count, medical data and initial electrocardiogram QRS scores of 811 eligible patients were examined. Procalcitonin levels were measured at the time of admission in all patients. Patients were classified into two groups according to their estimated infarct size by median values: QRS score 0.41 predicted the Selvester QRS score with a sensitivity of 72.8% and a specificity of 87.6% (area under the curve = 0.796, 95%: CI = 0.767- 0.823, p<0.001). Conclusion: Procalcitonin is a promising, simple biomarker with a similar accuracy to the Selvester QRS score in predicting the extent of infarct size.

Özet

Amaç: Selvester QRS skorunun değeri, ST segment yükselmeli miyokard enfarktüsü prognozunu öngörmede daha önceki çalışmalarla kanıtlanmıştır. Yüksek prokalsitonin düzeyleri, ST segment yükselmeli miyokard enfarktüsünde prognostik değere sahip yeni bir belirteç olarak bildirilmiştir. Bu çalışmada, ST segment yükselmeli miyokard enfarktüsü popülasyonunda serum prokalsitonin düzeyi ile Selvester skoru arasındaki ilişkinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Bu çalışma, ardışık 873 ST segment yükselmeli miyokard enfarktüsü tanılı hastayı kapsayıp, kesitsel gözlemsel olarak tasarlandı. Dışlama kriterlerinden sonra çalışmaya uygun 811 hastanın biyokimyasal, tam kan parametreleri, tıbbi verileri ve başlangıç elektrokardiyogram QRS skorları incelendi. Hastalar hospitalize edildikten sonra tüm hastaların prokalsitonin seviyeleri ölçüldü. Hastalar tahmini enfarktüs boyutlarına göre medyan değerler baz alınarak iki gruba ayrıldı: QRS skor 0,41 değeri ile Selvester QRS skoru, %72,8 duyarlılık ve %87,6 özgüllük ile (eğri altındaki alan=0,796, %95: CI=0,767-0,823, p<0,001) ile predikte edildi. Sonuç: Prokalsitonin, enfarktüs boyutunu tahmin etmede, Selvester QRS skoru ile benzer doğrulukta umut verici, basit bir biyolojik belirteçtir.

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Cite This Article

AŞKIN, L., AŞKIN, H. Ş. (2018). The Association Between Serum Procalcitonin Levels and Selvester QRS Score in ST Elevation Myocardial Infarction Patients. MN Kardiyoloji, Cilt: 25 - Sayı: 2, 52–59. https://ajindex.com/articles/297254

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