Journals / MN Kardiyoloji / 2017 / Cilt: 24 - Sayı: 2

A New Predictor of Amural Thrombus in Post Myocardial Infarction Patients: R2CHADS2 Score

Miyokard Enfarktüsü Sonrası Apikal Mural Trombüsü Öngermede Yeni Bir Skor: R2CHADS2 Skoru

Pages
50–55
DOI
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Conclusion: R2CHADS2 score is a simple and easily accessible test that can predict left ventricular apical thrombus formation.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Left ventricular apical thrombus formation are generally associated with ischemic and non-ischemic cardiomyopathies.
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Key Findings & Data:Components of R2CHADS2 had predictive value for both prognosis and complications of ischemic heart disease.
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Conclusion & Impact:Conclusion: R2CHADS2 score is a simple and easily accessible test that can predict left ventricular apical thrombus formation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Left ventricular apical thrombus formation are generally associated with ischemic and non-ischemic cardiomyopathies. Components of R2CHADS2 had predictive value for both prognosis and complications of ischemic heart disease. The aim of the study to investigate the association between R2CHADS2 score and left ventricular apical thrombus formation in post-MI patients. Material and Method: Forty-five patients with left ventricular apical thrombus and 28 patients without left ventricularapical thrombus were enrolled in this study. We evaluated post-myocardial infarction echocardiographic parameters of all patients. Results: There were no significant differences in terms of demographic features, echocardiographic and biochemical parameters be-tween two groups. There was a significant difference in terms of R2CHADS2 score between patients with and without apical thrombus (p =0.001). In univariate analysis, there was a significant correlation between R2CHADS2 score and the presence of thrombus. In multi-variate analysis, R2CHADS2 score was found to be an independent risk factor for the formation of apical thrombus. The receiver operat-ing characteristic analysis yielded a cutoff value of 4.5 for the R2CHADS2 score to predict apical thrombus, with sensivity and specifity of 62.2% and 68.9%, respectively. Conclusion: R2CHADS2 score is a simple and easily accessible test that can predict left ventricular apical thrombus formation.

Özet

Amaç: Sol ventrikül apikal trombüsleri genellikle iskemik ve noniskemik kardiyomiyopatilerle ilişkilidir. R2CHADS2 skorunu oluşturan kom-ponentler iskemik kalp hastalığının prognoz ve komplikasyonları için prediktif değere sahiptir. Bu araştırmanın amacı R2CHADS2 skoru ile sol ventrikül apikal trombüsü ile arasındaki ilişkiyi araştırmaktır. Gereç ve Yöntem: Sol ventriküler apikal trombüsü olan 45 hasta ve sol ventriküler apikal trombüsü olmayan 28 hasta çalışmaya dahil edildi. Tüm hastalara mİyokard enfarktüsü sonrası ekokardiyografik inceleme yapıldı. Bulgular: İki grup arasında demografik parametreler, ekokardiyografik ve biyokimyasal parametreler açısından fark yoktu. Apikal trom-büsü olan ve olmayan hasta grupları arasında R2CHADS2 skoru açısından anlamlı farklılık saptandı (p=0,001). Tek değişkenli analizde, R2CHADS2 skoru ile tromboz varlığı arasında anlamlı korelasyon mevcuttu. Çok değişkenli analizde, R2CHADS2 skorunun apikal trombü-sü oluşumu için bağımsız bir risk faktörü olduğu bulundu. ROC analizine göre R2CHADS2 skorunun 4,5’tan büyük olması %62,2 duyarlılık ve %68,9 özgüllük ile apikal trombüsü oluşumu öngördürücüsü olarak bulundu. Sonuç: R2CHADS2 skoru sol ventrikül apikal trombüs oluşumunu öngörmede basit ve ucuz bir test olarak kullanılabilir.

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Cite This Article

ÜNAL, S., AÇAR, B., YAYLA, Ç., ERTEM, A. G., KARANFİL, M., EFE, T. H., ÇELEBİ, Ö. Ö., TEMİZHAN, A., AYDOĞDU, S. (2017). A New Predictor of Amural Thrombus in Post Myocardial Infarction Patients: R2CHADS2 Score. MN Kardiyoloji, Cilt: 24 - Sayı: 2, 50–55. https://ajindex.com/articles/297219

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