Journals / MN Oftalmoloji / 2004 / Cilt: 11 - Sayı: 2

The relationship between diabetic retinopathy and serum levels of calcium, magnesium and fibrinogen

Diabetik retinopati ile serum kalsiyum, magnezyum ve fibrinojen düzeyleri arasındaki ilişki

Pages
179–181
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further studies are needed to understand the etiopathogenesis of diabetic retinopathy in which multifactorial mechanisms play role.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To investigate the relationship between the diabetic retinopathy and the levels of serum calcium, magnesium and fibrinogen in patients with type 2 diabetes mellitus (DM).
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Key Findings & Data:Material and Method: Patients with type 2 diabetes mellitus recorded at Adnan Menderes University Medical Faculty, Department of Ophthalmology, Retina unit were included in the study.
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Conclusion & Impact:Further studies are needed to understand the etiopathogenesis of diabetic retinopathy in which multifactorial mechanisms play role.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Fibrinojen · Kalsiyum · Diabetes mellitus

Abstract

Purpose: To investigate the relationship between the diabetic retinopathy and the levels of serum calcium, magnesium and fibrinogen in patients with type 2 diabetes mellitus (DM). Material and Method: Patients with type 2 diabetes mellitus recorded at Adnan Menderes University Medical Faculty, Department of Ophthalmology, Retina unit were included in the study. Of the patients, 31 cases had no retinopathy, 30 cases had nonproliferative diabetic retinopathy and 32 cases had proliferative diabetic retinopathy. Thirty cases were taken as the control group. Serum levels of magnesium, calcium and fibrinogen were analyzed. Results were compared with variance analyses. Results: Serum levels of calcium in patients with no retinopathy, nonproliferative diabetic retinopathy and proliferative diabetic retinopathy were significantly higher from control group. Serum magnesium and fibrinogen levels were not statistically different between patient groups and control group. Conclusion: In this study, serum calcium level was found significantly higher in patients with type II DM from control group. Further studies are needed to understand the etiopathogenesis of diabetic retinopathy in which multifactorial mechanisms play role.

Özet

Amaç: Tip II diabetes mellituslu (DM) olgularda serum kalsiyum, magnezyum ve fibrinojen düzeyleri ile diabetik retinopati arasındaki ilişkinin araştırılması. Gereç ve Yöntem: Adnan Menderes Üniversitesi Tıp Fakültesi Göz Hastalıkları Anabilim Dalı Retina Birimine kayıtlı tip II DM'lu 93 olgu çalışma kapsamına alındı. Olguların 31'i retinopatisi olmayan, 30'u nonproliferatif retinopatili, 32'si ise proliferatif retinopatili olgulardı. 30 olgu kontrol grubu olarak alındı. Olgularda açlık kan şekeri, serum kalsiyum, magnezyum ve fibrinojen düzeyleri ölçüldü. Sonuçlar tek yönlü varyans analizi ile karşılaştırıldı. Bulgular: Serum kalsiyum düzeyi, retinopatisi olmayan diabetik, nonproliferatif diabetik retinopatili ve proliferatif diabetik retinopatili olgularda kontrol grubuna oranla anlamlı derecede daha yüksek bulundu (p<0.05). Diabetik gruplar arasında serum kalsiyum düzeyi açısından anlamlı farklılık saptanmadı. Serum magnezyum ve fibrinojen düzeylerinde ise kontrol grubu ile diabetik olgular arasında ve diabetik grupların kendi arasında anlamlı fark gözlenmedi. Sonuç: Bu çalışmada, tip II DM'lu olgularda serum kalsiyum düzeyleri kontrollere göre istatistiksel olarak anlamlı yüksek bulundu. Multifaktöryel mekanizmaların rol oynadığı diabetik retinopati etyopatogenezinin aydınlatılabilmesi için daha geniş kapsamlı çalışmaların yapılması gerektiği kanaatindeyiz.

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Cite This Article

DÜNDAR, O. S., SAKARYA, R., KIR, E., AKTUNÇ, T. O. (2004). The relationship between diabetic retinopathy and serum levels of calcium, magnesium and fibrinogen. MN Oftalmoloji, Cilt: 11 - Sayı: 2, 179–181. https://ajindex.com/articles/296174

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