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Journals / MN Oftalmoloji / 2013 / Cilt: 20 - Sayı: 2

Evaluation of the relationship between the blood hormone levels and ocular response analyzer and pascal dynamic contour tonometer measurements in patients with thyroid disease without ophthalmopathy

Oftalmopati Gelişmemiş Tiroid Hastalarında Kan Hormon seviyeleri ile oküler cevap analizörü ve pascal dinamik kontur tonometre ölçümlerinin ilişkilerinin incelenmesi

Canan Aslı UTİNE
Şule ZİYLAN
Muhsin ALTUNSOY
Destan Nil KULAÇOĞLU
Halit PAZARLI
Ferda ÇİFTÇİ
Pages
117–122
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results of the two groups were compared and correlation of these measurements with blood free T3, free T4 and thyroid stimulating hormone (TSH) levels of were analysed.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Evaluation of the relationship between the Ocular Response Analyzer (ORA) and Pascal Dynamic Countour Tonometer (DCT) mesurements and blood hormone levels in pa- tients with thyroid disease without eye involvement.
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Key Findings & Data:Material and Method: Corneal hysteresis (CH), corneal resistance factor (CRF), Goldman correlated and corneal compansated intraocular pressure (IOPg and IOPcc, respectively) and ultrasonic central corneal thickness (CCT) measurements with ORA and OPA measurements with DCT were performed in a total of 16 eyes of 8 patients under treatment for hypothyroidy (Group 1) and 16 eyes of 8 patients under treatment for hyperthyroidy (Group 2) in the Endocrinology Department.
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Conclusion & Impact:Results of the two groups were compared and correlation of these measurements with blood free T3, free T4 and thyroid stimulating hormone (TSH) levels of were analysed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Evaluation of the relationship between the Ocular Response Analyzer (ORA) and Pascal Dynamic Countour Tonometer (DCT) mesurements and blood hormone levels in pa- tients with thyroid disease without eye involvement. Material and Method: Corneal hysteresis (CH), corneal resistance factor (CRF), Goldman correlated and corneal compansated intraocular pressure (IOPg and IOPcc, respectively) and ultrasonic central corneal thickness (CCT) measurements with ORA and OPA measurements with DCT were performed in a total of 16 eyes of 8 patients under treatment for hypothyroidy (Group 1) and 16 eyes of 8 patients under treatment for hyperthyroidy (Group 2) in the Endocrinology Department. Results of the two groups were compared and correlation of these measurements with blood free T3, free T4 and thyroid stimulating hormone (TSH) levels of were analysed.

Özet

Amaç: Göz tutulumu gelişmemiş tiroid hastalarında Oküler Cevap Analizörü (OCA) ve Pascal Dinamik Kontur Tonometre (DKT) ölçümlerinin kan hormon seviyeleri ile ilişkilerinin incelenmesi. Gereç ve Yöntem: Endokrinoloji kliniğinde hipotiroidi nedeniyle tedavi gören 8 olgunun 16 gözü (Grup 1) ile hipertiroidi nedeniyle tedavi gören 8 olgunun 16 gözünde (Grup 2) OCA ile kornea histerezisi (KH), kornea direnç faktörü (KDF), Goldman uyumlu ve kornea kom- panse göz içi basıncı (sırasıyla GİBg ve GİBkk) ölçümleri, ultrasonik merkezi kornea kalınlı- ğı (MKK) ölçümü ve DKT ile oküler nabız genliği (ONG) ölçümleri yapıldı. Sonuçlar iki grup arasında karşılaştırıldı ve ölçüm sonuçlarının hastaların kanda serbest T3, serbest T4 ve tiro- id uyarıcı hormon (TSH) değerleri ile korelasyonu incelendi. Bulgular: Sırasıyla Grup 1 ve Grup 2’de serum TSH seviyesi 3,90±4,76μmol ve 0,46±1,10 μmol; KH 10,63±1,28mmHg ve 10,24±1,25mmHg; KDF 10,54±1,22mmHg ve 10,06±1,59mm Hg; GİBg 15.23±3.54mmHg ve 14.99±2.50mmHg; GİBkk 15.50±3.78mmHg ve 15.73±2.01 mmHg; MKK 530,07±23,54μm ve 533,57±46,37μm; ONG 2,65±0,87mmHg ve 2,86±1,06mm Hg idi (hepsi için p>0,05). Olguların tümü birlikte değerlendirildiğinde serbest T3 seviyesi ile MKK, KH and KDF değerleri arasında anlamlı negatif korelasyon saptandı (sırasıyla r(18)=- 0,590, p=0,01; r(18)=-0,494, p=0,03; r(18)=-0,582, p<0,01). Sonuç: Tiroid oftalmopati gelişmemiş hipotiroidi ve hipertiroidili olgularda serum serbest T3 seviyesi ile korneanın kalınlık ve viskoelastik özellikleri arasında anlamlı negatif korelas- yon saptanmıştır.

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Cite This Article

UTİNE, C. A., ZİYLAN, Ş., ALTUNSOY, M., KULAÇOĞLU, D. N., PAZARLI, H., ÇİFTÇİ, F. (2013). Evaluation of the relationship between the blood hormone levels and ocular response analyzer and pascal dynamic contour tonometer measurements in patients with thyroid disease without ophthalmopathy. MN Oftalmoloji, Cilt: 20 - Sayı: 2, 117–122. https://ajindex.com/articles/295701

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