Journals / MN Oftalmoloji / 2017 / Cilt: 24 - Sayı: 1

The Clinical Features and Course in Posner Schlossman Syndrome

Posner Schlossman Sendromunda Klinik Özellikler ve Seyir

Pages
30–32
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Ocular damages can be minimized if the patients informed well and if followed-up regularly and treated appropriately

📌 3 Key Takeaways

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Objective & Hypothesis:To evaluate the clinical features and prognosis in long term followed-up patients with Posner Schlossman Syndrome.
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Key Findings & Data:The mean age of the patients at diagnosis was 34.2±12.5 (21-55) years.
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Conclusion & Impact:Ocular damages can be minimized if the patients informed well and if followed-up regularly and treated appropriately
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

To evaluate the clinical features and prognosis in long term followed-up patients with Posner Schlossman Syndrome. Material and Method: The patients with Posner Schlossman Syndrome were evaluated retrospectively. The demographic characteristics of the patients, age of the patients at diagnosis, the findings of ocular examination at follow-up visits, the visual acuity, the intraocular pressure, the cup/disc ratio, the visual field values and the number of attacks were analysed. Results: Posner Schlossman Syndrome was diagnosed in fifteen eyes of fourteen patients. The mean age of the patients at diagnosis was 34.2±12.5 (21-55) years. In two eyes of one patient attacks were seen at different times. The mean follow-up time of the patients and the number of attacks were 59.6±24.8 (16-120) months and 4.9±2.3 (2-9) respectively. Visual acuity decresaed from 20/20 to 20/25 in one eye and from 20/20 to 20/32 in the other. The cup/disc ratio values were 0.26±0.06 and 0.28 ± 0.09 at first and last visits, respectively, and there were no statistically significant differences between the first and last visits values (p=0.180). At first and last visits, the mean values of mean deviation (MD) in visual field tests were -1.3±1.0, and -1.7±1.2 and pattern standard deviation were 2.1±0.7 and 2.2±0.9 respectively. There were no statistically significant differences (p=0.221, p=0.343). During the acute attack, the maximum mean intraocular pressure was 37.1±8.2 (27-55) mmHg. These values decreased to 16.8±1.6 (14-22) mmHg with topical antiglaucoma medication and during the period without attack. In one eye, due to high intraocular pressure course after attack, antiglaucoma medication was continued. In another patient, intraocular pressure didn’t decrease despite medical treatment and trabeculectomy was performed. Conclusion: Posner Schlossman Syndrome is a chronic disease characterised by slight uveal inflammation andintraocular pressure increase during attacks. Ocular damages can be minimized if the patients informed well and if followed-up regularly and treated appropriately

Özet

Amaç: Posner Schlossman Sendromu hastalarında klinik özelliklerin ve uzun dönem takiplerindeki prognozun değerlendirilmesi. Gereç ve Yöntem: Hastalara ait veriler retrospektif olarak incelendi. Hastaların demografik özellikleri, ilk tanı sırasındaki yaşı, tanı ve takiplerdeki oküler muayene bulguları, görme keskinliği, göz içi basıncı, çanaklaşma/disk oranı, görme alanı değerleri mean deviasyon, paternstandart deviyasyon ve atak sayısı incelendi.Bulgular: 14 hastanın 15 gözüne Posner Schlossman Sendromu tanısı konmuştu. İlk tanı sırasında ortalama yaş 34,2±12,5 yıldı.Bir hastanın farklı zamanlarda olmak üzere her iki gözünde de atak gelişmişti. Ortalama takip süresi ve sayısı sırasıyla 59,6±24,8 ayve 4,9±2,3 idi. Görme keskinliği bir gözde 20/20'den 20/25'e, bir diğer gözde 20/20'den 20/32'ye düşmüştü. İlk ve son kontroldeki çanaklaşma/disk oranı değerleri sırasıyla 0,26 ± 0,06 ve 0,28 ± 0.09 olup, ilk ve son kontroldeki değerler arasında istatistiksel olarak anlamlıfark yoktu (p=0,180). İlk ve son kontroldeki görme alanı değerleri sırasıyla mean deviyasyon -1,3±1,0 ve -1,7±1,2, patern standart deviyasyon2,1±0,7 ve 2,2±0,9 olup, ilk ve son değerler arasında istatistiksel olarak anlamlı fark yoktu (p=0,221 ve p=0,343). Akut atak boyunca ortalama göz içi basıncı 37,1±8,2 mmHg iken, topikal antiglokomatöz tedavi ile ortalama göz içi basıncı 16,8±1,6 mmHg'yedüşmüştü. Bir gözde atak sonrası devam eden yüksek göz içi basıncı değerleri nedeniyle antiglokomatöz tedaviye devam edildi. Bir diğer hastada göz içi basıncı medikal tedaviye rağmen düşmedi ve bu hastaya trabekülektomi yapıldı.Sonuç: Posner Schlossman Sendromu ataklar sırasında hafif üveal enflamasyon ve göz içi basıncı artışı ile karakterize kronik bir hastalıktır. Oküler hasar, hastalar iyi bilgilendirilir ve düzenli takip edilip, uygun şekilde tedavi edilirse minimize edilebilir

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Cite This Article

Takmaz, T., ÇAĞLAYAN, M., AKMEŞE, H. E. (2017). The Clinical Features and Course in Posner Schlossman Syndrome. MN Oftalmoloji, Cilt: 24 - Sayı: 1, 30–32. https://ajindex.com/articles/295542

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References (19)

  1. Posner A, Schlossman A. Syndrome of unilateral recurrent attacks of glaucoma with cyclitic symptoms. Arch Ophthalmol 1948; 39: 517-35
  2. Shazly TA, Aljajeh M, Latina MA. Posner-Schlossman glaucomatocyclitic crisis. Semin Ophthalmol 2011;26:282-28
  3. Sangha SS. Posner Schlossman syndrome. Ophthalmology 2002; 109:409
  4. Kim R, Van Stavern G, Juzych M. Nonarteritic anterior ischemic optic neuropathy associated with acute glaucoma secondary to Posner-Schlossman syndrome. Arch Ophthalmol 2003;121:127-8
  5. Irak I, Katz BJ, Zabriskie NA, Zimmerman PL. Posner Schlossman syndrome and nonarteritic anterior ischemic optic neuropathy. J Neuroophthalmol 2003;23:264-7
  6. Jap A, Sivakumar M, Chee SP. Is Posner-Schlossman syndrome benign? Ophthalmology 2001;108:913-8
  7. Shen SC, Ho WJ, Wu SC, et al. Peripheral vascular endothelial dysfunction in glaucomatocyclitic crisis: a preliminary study. Invest Ophthalmol Vis Sci 2010;51:272-6
  8. Knox DL. Glaucomatocyclitic crises and systemic disease: peptic ulcer, other gastrointestinal disorders, allergy and stress. Trans Am Ophthalmol Soc 1988;86:473-95
  9. Hirose S, Ohno S, Matsuda H. HLA-Bw54 and glaucomatocyclitic crisis. Arch Ophthalmol 1985;103:1837-9
  10. Teoh SB, Thean L, Koay E. Cytomegalovirus in aetiology of Posner-Schlossman syndrome: evidence from quantitative polymerase chain reaction. Eye (Lond) 2005;19:1338-40
  11. Chee SP, Jap A. Cytomegalovirus anterior uveitis: outcome of treatment. Br J Ophthalmol 2010;94:1648-52
  12. Hedayatfar A, Chee SP. Posner Schlossman syndrome associated with cytomegalovirus infection: a case series from a non-endemic area. Int Ophthalmol 2014;13
  13. Bayraktutar B.N, Tekeli O, Tekeli A, Yalçındağ N. PosnerSchlossman sendromunda sitomegalavirüs pozitifliği. Glo-Kat 2015;10:224-6
  14. Yamamoto S, Pavan-Langston D, Tada R, et al. Possible role of herpes simplex virus in the origin of PosnerSchlossman syndrome. Am J Ophthalmol 1995;119:796-8
  15. Takusagawa HL, Liu Y, Wiggs JL. Infectious theories of Posner Schlossman syndrome. Int Ophthalmol Clin 2011;51:105-115
  16. Shazly TA, Aljajeh MA, Latina MA. Posner-Schlossman Glauco - matocyclitic Crisis. Semin Ophthalmol 2011;26: 282-4
  17. Kass MA, Becker B, Kolker AE. Glaucomatocyclitic crisis and primary open angle glaucoma. Am J Ophthalmol 1973;75:668- 673
  18. Darchuk V, Sampaolesi J, Mato L, Nicoli C, Sampaolesi R. Optic nerve head behavior in Posner-Schlossman syndrome. Int Ophthalmol 2001;23:373-379
  19. Dinakaran S, Kayarkar V.