Journals / MN Oftalmoloji / 2021 / Cilt: 28 - Sayı: 1

Limbal Stem Cell Transplantation and Penetran Keratoplasty in Patient with Corneal Chemical Burn Scar

Korneada Kimyasal Yanık İzi Olan Hastada Limbusa Kök Hücre Nakli ve Penetran Keratoplasti

Pages
63–66
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

After 3 months from the second surgery, the patient had a clear corneal graft and his visual acuity increased to 0.15 on decimal scale.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The patient complaining low vision on his right eye applied to our clinic.
📊
Key Findings & Data:Central corneal scar persisted during follow up, however his vision increased to finger count from 2 meters.
💡
Conclusion & Impact:After 3 months from the second surgery, the patient had a clear corneal graft and his visual acuity increased to 0.15 on decimal scale.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The patient complaining low vision on his right eye applied to our clinic. On the biomicroscopic exam vascularized corneal leukoma was detected. The patient’s eye had an exposure to plaster and lime mixture five years ago. His visual acuity on the right eye was hand movements. Amniotic membrane transplantation and autologous limbal stem cell transplantation from the fellow eye was performed to the patient with limbal stem cell deficiency. Central corneal scar persisted during follow up, however his vision increased to finger count from 2 meters. After 6 months penetrating keratoplasty and autologous limbal stem cell transplantation with amniotic membrane transplantation were performed in the second surgery session. After 3 months from the second surgery, the patient had a clear corneal graft and his visual acuity increased to 0.15 on decimal scale.

Özet

Sağ gözünde az görme şikayetiyle kliniğimize başvuran, beş yıl önce gözüne alçı ve kireç karışımına maruz kalan hastanın biyomikroskopik muayenesinde vaskülarize korneal lökom tespit edildi. Hastanın görme keskinliği el hareketi düzeyindeydi. Limbal hücre yetmezliği olan hastaya önce amniyon membran transplantasyonu ile birlikte diğer gözünden otolog limbal kök hücre transplantasyonu yapıldı. Kontrollerinde görme keskinliği 2 metreden parmak sayma (mps) düzeyine ulaşan hastada santral korneal alanda iz tespit edil-mesi üzerine ikinci bir ameliyatla penetran keratoplasti, amniyon membran transplantasyonu ve otolog limbal kök hücre transplantasyonu işlemi yapıldı. Postoperatif üçüncü ay kontrolünde hastanın görme keskinliğinin Snellen eşeline göre 0,15 düzeyine yükseldiği tespit edildi.

🔖

Cite This Article

HAN, Ç. Ç., ÇINAR, Y. (2021). Limbal Stem Cell Transplantation and Penetran Keratoplasty in Patient with Corneal Chemical Burn Scar. MN Oftalmoloji, Cilt: 28 - Sayı: 1, 63–66. https://ajindex.com/articles/295307

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Sangwan VS. Basu S. MacNeil S. Balasubramanian D. Simple limbal epithelial transplantation (SLET): a novel surgical technique for the treatment of unilateral limbal stem cell deficiency. Br J Ophthalmol. 2012;96(7):931-4
  2. Haring RS. Sheffield ID. Channa R. Canner JK. Schneider EB. Epidemiologic trends of chemical ocular burns in the United States. JAMA Ophthalmol. 2016;134(10):1119-24
  3. Grant WM. Thomas CC. Toxicology of the eye, third edition. J Toxicol Cutan Ocul Toxicol. 1987;6(2):155-6
  4. Moon ME. Robertson IF. Retrospective study of alkali burns of the eye. Aust J Ophthalmol. 1983;11(4):281-6
  5. Friedenwald JS, Hughes WF. Herrmann H. Acid burns of the eye. Arch Ophthalmol. 1946;35(2):98-108
  6. Roper-Hall MJ. Thermal and chemical burns. Trans Ophthalmol Soc UK. 1965;85:631-53
  7. Bizrah M. Yusuf A. Ahmad S. An update on chemical eye burns. Eye (Lond). 2019;33(9):1362-77
  8. Kam K. Patel C. Nikpoor N. Yu M. Basu S. Limbal ischemia: Reliability of clinical assessment and implications in the manage-ment of ocular burns. Indian J Ophthalmol. 2019;67(1):32-6
  9. Saghizadeh M. Kramerov AA. Svendsen CN, Ljubimov AV. Concise Review: Stem Cells for Corneal Wound Healing. Stem Cells. 2017;35(10):2105-14
  10. Shanbhag SS. Saeed HN, Paschalis EI. Chodosh J. Keratolimbal allograft for limbal stem cell deficiency after severe corneal chemical injury: a systematic review. Br J Ophthalmol. 2018;102(8):1114-21.