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Journals / Molecular Imaging and Radionuclide Therapy / 2014 / Cilt: 23 - Sayı: 1

FDG-PET/BT’de malignite ile karışan multi-fokal kemik tüberkülozu ve mediastinal lenfadenit: olgu sunumu

Multifoci bone tuberculosis and lymphadenitis in mediastinum mimics malignancy on FDG-PET/CT: A Case Report

Nalan SELÇUK ALAN
AYŞEN FENERCİOĞLU
H. Hakan SELÇUK
Çağatay ULUÇAY
Esin YENCİLEK
Pages
39–42
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We present a 60-year-old woman with lytic bone lesions and mediastinal hypermetabolic foci, initially suspected to be malignant by means of FDG-PET and the other imaging modalities; however, bone biopsy confirmed the diagnosis of bone tuberculosis.

📌 3 Key Takeaways

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Objective & Hypothesis:Positron Emission Tomography with 2-deoxy-[F-18]-fluoro-D-glucose (FDG-PET) has become a reliable diagnostic tool in clinical practice similar to Magnetic Resonance (MR) imaging and Computed Tomography (CT).
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Key Findings & Data:Bone tuberculosis may be confused with malignant tumors of bone and its metastases, and can accumulate focally increased FDG in active period.
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Conclusion & Impact:We present a 60-year-old woman with lytic bone lesions and mediastinal hypermetabolic foci, initially suspected to be malignant by means of FDG-PET and the other imaging modalities; however, bone biopsy confirmed the diagnosis of bone tuberculosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Positron Emission Tomography with 2-deoxy-[F-18]-fluoro-D-glucose (FDG-PET) has become a reliable diagnostic tool in clinical practice similar to Magnetic Resonance (MR) imaging and Computed Tomography (CT). FDG-PET has especially been used to differentiate malignant from benign lesions, and for staging and follow- up malignant tumors. However, FDG-PET has some pitfalls in cancer screening and FDG tracer accumulates at sites of infection and inflammation. Bone tuberculosis may be confused with malignant tumors of bone and its metastases, and can accumulate focally increased FDG in active period. We present a 60-year-old woman with lytic bone lesions and mediastinal hypermetabolic foci, initially suspected to be malignant by means of FDG-PET and the other imaging modalities; however, bone biopsy confirmed the diagnosis of bone tuberculosis.

Özet

[F-18]-floro-deoksi-glikoz Pozitron Emisyon Tomografisi (FDG-PET), klinik uygulamalarımızda Manyetik Rezonans (MR) ve Bilgisayarlı Tomografi (BT) gibi güçlü bir tanı aracı haline gelmiştir. Özellikle lezyonların benign malign ayrımında, malign tümörlerin evrelendirilmesinde ve takibinde kullanılmaktadır. Ancak FDG-PET tümöre spesifik bir yöntem değildir ve infeksiyon/ inflamasyon gibi durumlarda da FDG birikimi görülebilir. Kemik tüberkülozu kemiğin malign tümörü veya metastazları ile karışabilir ve aktif dönemde ise artmış FDG tutulumu gösterebilir. Bu yazıda diğer görüntüleme tekniklerinde ve FDG-PET’de malign gibi gözüken kemikte litik lezyonları ve mediastende malignite düzeyinde hipermetabolik lenf adenopatileri mevcut olan 60 yaşındaki kadın olgu sunulmaktadır. İlk planda malignite lehine değerlendirilen olguda, tanıyı teyit amaçlı yapılan mediastenoskopik incelemede ve kemik biyopsisinde tüberkülozis tanısı kondu

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Cite This Article

ALAN, N. S., FENERCİOĞLU, A., SELÇUK, H. H., ULUÇAY, Ç., YENCİLEK, E. (2014). FDG-PET/BT’de malignite ile karışan multi-fokal kemik tüberkülozu ve mediastinal lenfadenit: olgu sunumu. Molecular Imaging and Radionuclide Therapy, Cilt: 23 - Sayı: 1, 39–42. https://ajindex.com/articles/295216

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