Journals / Nöropsikiyatri Arşivi / 2015 / Cilt: 52 - Sayı: 2

The Effects of Cognitive Rehabilitation on Relapsing Remitting Multiple Sclerosis Patients

Relaps ve Remisyonla Seyreden Multipl Skleroz Olgularında Kognitif Rehabilitasyonun Etkileri

Pages
174–179
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This approach is hopeful and further comprehensive studies are needed.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: The aims of this study were to determine the severity of cognitive impairment with Brief Repeatable Battery Neuropsychology (BRB-N) and to show the benefits of cognitive rehabilitation programs to develop coping strategies for the retardation of cognitive losses in relapsing remitting multiple sclerosis (RRMS) patients.
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Key Findings & Data:Methods: The cognitive screening with BRB-N was performed in RRMS patients who had applied to the MS outpatient clinic of Bakırköy Psychiatric and Neurological Diseases Hospital, had an Expanded Disability Status Scale (EDSS) score between 1.0 and 5.5, and had no other cognitive disease or used drugs that effected the cognitive status.
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Conclusion & Impact:This approach is hopeful and further comprehensive studies are needed.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: The aims of this study were to determine the severity of cognitive impairment with Brief Repeatable Battery Neuropsychology (BRB-N) and to show the benefits of cognitive rehabilitation programs to develop coping strategies for the retardation of cognitive losses in relapsing remitting multiple sclerosis (RRMS) patients. Methods: The cognitive screening with BRB-N was performed in RRMS patients who had applied to the MS outpatient clinic of Bakırköy Psychiatric and Neurological Diseases Hospital, had an Expanded Disability Status Scale (EDSS) score between 1.0 and 5.5, and had no other cognitive disease or used drugs that effected the cognitive status. Thirty two patients with cognitive impairment underwent consecutive computer-assisted cognitive rehabilitation program once a week for 8 weeks conducted by psychologists. The effects of the program were evaluated with the tests repeated every 4 weeks. Results: The mean age of the patients was 36.09±7.19 years. Their initial and control test scores were found to be paced auditory serial addition test (PASAT) 29.21±17.97; 42.43±15.43, Selective Reminding Test-Total Learning (SRT-TL) 8.03±2.36; 10.09±1.77, Selective Reminding TestLong-term Memory (SRT-DR) 6.72±2.74; 9±2.29, Spatial Recall TestTotal Learning (SPART-TL) 4.72±2.02; 4.22±1.74, Spatial Recall TestLong-term Memory (SPART-DR) 5.94±2.54; 5.16±2.23, Symbol Digit Modalities Test (SDMT) 40.44±17.04; 46.47±17.94, Word Fluency Test (WLG) 32.88±9.87; 40.44±9.95 respectively. There was no significant statistical difference between Multiple Sclerosis Neuropsychological Screening Questionnaire (MSNQ) and SPART values of preface, 1st control and 2nd control (p>0.05). There was significant statistical difference between PASAT, WLG, SDMT, SRT-TL, SRT-DR values of Preface, 1st control, and 2nd control (p=0.0001). Conclusion: It was determined that on distinctive improvement on sustaining attention, working memory and information processing speed, and verbal fluency and verbal learning with cognitive rehabilitation, no changes were observed on visuospatial learning. This approach is hopeful and further comprehensive studies are needed.

Özet

Amaç: Relaps ve remisyonla seyreden multipl skleroz (RRMS) olgularında Brief Repeatable Battery Neuropsychology (BRB-N) ile kognitif bozukluk şiddetinin belirlenerek, bilişsel kayıpların yavaşlatılması ve başa çıkma stratejileri geliştirilmesi için yürütülen kognitif rehabilitasyon programlarının faydalarının gösterilmesi amaçlanmıştır. Yöntem: Bakırköy Ruh ve Sinir Hastalıkları Hastanesi MS polikliniğine baş- vuran RRMS tanısı almış, Expanded Disability Status Scale (EDSS) 1,0-5,5 arasında, kognitif durumunu etkileyecek hastalığı ya da ilaç kullanımı olmayan hastalara BRB-N ile kognitif tarama yapılmıştır. Kognitif bozukluk saptanan 32 hasta, ardışık 8 hafta süresince haftada 1 kez psikolog eşliğinde bilgisayar destekli kognitif rehabilitasyon programına alınmış; 4 hafta arayla tekrarlanan testlerle kognitif rehabilitasyon programının etkileri değerlendirilmiştir. Bulgular: Yaş ortalaması 36,09±7,19 olan hastaların sırasıyla giriş ve kontrol test skorları: PASAT 29,21±17,97; 42,43±15,43, seçici hatırlama testi-total öğrenme (SRT-TL) 8,03±2,36; 10,09±1,77, seçici hatırlama testi-uzun süreli bellek (SRT-DR) 6,72±2,74; 9±2,29, görsel bellek testi-total öğrenme (SPART-TL) 4,72±2,02; 4,22±1,74, görsel bellek testi-uzun süreli bellek (SPART-DR) 5,94±2,54; 5,16±2,23, sembol sayı modaliteleri testi (SDMT) 40,44±17,04; 46,47±17,94, kelime akıcılığı (WLG) 32,88±9,87; 40,44±9,95 olarak bulunmuştur. Başlangıç, 1. kontrol, 2. kontrol MSNQ (Multiple Sclerosis Neuropsychological Screening Questionare) ve SPART değerleri arasında istatistiksel olarak anlamlı farklılık gözlenmemiştir (p>0,05). Başlangıç, 1. kontrol, 2. kontrol PASAT, WLG, SDMT, SRT-TL ve SRT-DR değerleri arasında istatistiksel olarak çok anlamlı farklılık gözlenmiştir (p=0,0001). Sonuç: Kognitif rehabilitasyon ile dikkati sürdürme, çalışma belleği ve bilgi işleme hızında, verbal akıcılık ve verbal öğrenmede belirgin düzelme saptanmıştır, vizyospasyal öğrenme üzerinde değişiklik gözlenmemiştir. Bu uygulama umut vaad etmekle beraber daha kapsamlı çalışmalara ihtiyaç olduğunu göstermiştir.

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Cite This Article

ALTUN, İ. G., KIRBAŞ, D., ALTUN, D. U., SOYSAL, A., SUTLAS, P. N., KUŞÇU, D. Y., GAYIR, N. B., ARSLAN, E., TOPÇULAR, B. (2015). The Effects of Cognitive Rehabilitation on Relapsing Remitting Multiple Sclerosis Patients. Nöropsikiyatri Arşivi, Cilt: 52 - Sayı: 2, 174–179. https://ajindex.com/articles/294394

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