Journals / Ondokuz Mayıs Üniversitesi Tıp Dergisi (. Journal of Experimental and Clinical Medicine) / 1999 / Cilt: 16 - Sayı: 2

Perinatal asfiksi ve trombositopeni

Perinatal asphyxia and thrombocytopenia

Pages
100–105
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We couldn't find any effect of the thrombocytopenia on mortality in perinatal asphyxia, Moreover, the severity of hypoxic ischemic encephalopathy didn't show any relation with platelet count.

📌 3 Key Takeaways

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Objective & Hypothesis:In this study, thrombocytopenia incidence and the mechanism responsible for the thrombocytopenia in asphyxiated infants were investigated within 2 weeks of life.
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Key Findings & Data:We studied 24 full-term newborn infants with asphyxia and 10 term healthy newborns, Thrombocytopenia developed in 25% of the infants in 0-2 days, 36.8% in 3-6 days and 26.6% in 7-14 days after birth.
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Conclusion & Impact:We couldn't find any effect of the thrombocytopenia on mortality in perinatal asphyxia, Moreover, the severity of hypoxic ischemic encephalopathy didn't show any relation with platelet count.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Asfiksi neonatorum · Trombositopeni · Süt çocuğu

Abstract

In this study, thrombocytopenia incidence and the mechanism responsible for the thrombocytopenia in asphyxiated infants were investigated within 2 weeks of life. We studied 24 full-term newborn infants with asphyxia and 10 term healthy newborns, Thrombocytopenia developed in 25% of the infants in 0-2 days, 36.8% in 3-6 days and 26.6% in 7-14 days after birth. The mortality ratio in perinatal asphyxia was 29.1% and only one patient had thrombocytopenia. Although the mean platelet volume values of asphyxiated-thrombocytopenic patients were higher than those of the asphyxiated-nonthrombocytopenic patients, no statistical difference was found. We couldn't find any effect of the thrombocytopenia on mortality in perinatal asphyxia, Moreover, the severity of hypoxic ischemic encephalopathy didn't show any relation with platelet count.

Özet

Bu çalışmada asfiktik term yenidoğanlarda hayatın ilk iki haftası içinde trombositopeni insidansı ve trombositopeniden sorumlu mekanizma araştırıldı. 24 asfiksili bebek ve 10 sağlıklı bebek çalışıldı. Asfiktik bebeklerde hayatın ilk iki günü içinde %25.0, 3-6. günlerde %36.8 ve 7-14. günlerde %26.6 oranında trombositopeni gelişti. Perinatal asfiksili infantlarda mortalite oranı %29.1'di ve yalnızca bir hastada trombositopeni vardı. Bu çalışmada perinatal asfikside trombositopeninin mortalite üzerine etkisi bulunamadı. Asfiktik trombositopenik hastaların ortalama trombosit volümü asfiktik nontrombositopenik bebeklerden yüksek olmasına rağmen istatistiksel fark gözlenmedi. Ayrıca hipoksik-iskemik ensefalopati şiddeti trombosit sayısıyla ilişkili değildi.

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Cite This Article

BELET, N., KÜÇÜKÖDÜK, Ş., SANCAK, R., UYSAL, S. (1999). Perinatal asfiksi ve trombositopeni. Ondokuz Mayıs Üniversitesi Tıp Dergisi (. Journal of Experimental and Clinical Medicine), Cilt: 16 - Sayı: 2, 100–105. https://ajindex.com/articles/293427