Journals / Nöropsikiyatri Arşivi / 2016 / Cilt: 53 - Sayı: 2

Withdrawal-Emergent Dyskinesia and Supersensitivity Psychosis Due to Olanzapine Use

Olanzapin Kullanımına Bağlı Çekilme Diskinezisi ve Süpersensitivite Psikozu

Pages
178–180
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study, a case of WE-D because of discontinuing olanzapine use and supersensitivity psychosis is discussed.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Tardive dyskinesia (TD) usually appears after years of antipsychotic drug use and appears to be related to the total lifetime medication dose.
📊
Key Findings & Data:In withdrawal-emergent dyskinesia (WE-D), which is considered to be a subtype of TD, dyskinetic symptoms often appear shortly after a rapid reduction in antipsychotic drug dose or sudden discontinuation of the drug.
💡
Conclusion & Impact:In this study, a case of WE-D because of discontinuing olanzapine use and supersensitivity psychosis is discussed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Tardive dyskinesia (TD) usually appears after years of antipsychotic drug use and appears to be related to the total lifetime medication dose. In withdrawal-emergent dyskinesia (WE-D), which is considered to be a subtype of TD, dyskinetic symptoms often appear shortly after a rapid reduction in antipsychotic drug dose or sudden discontinuation of the drug. Supersensitivity psychosis, which is frequently observed along with TD and is considered to have a similar etiology as TD, is a psychotic relapse phenomenon that occurs after the withdrawal of an antipsychotic drug or a rapid reduction in the drug dosage. In general, atypical antipsychotics tend to be associated with less propensity to cause TD when compared with typical antipsychotics. Furthermore, olanzapine and clozapine may have a therapeutic potential in improving or totally curing TD. In this study, a case of WE-D because of discontinuing olanzapine use and supersensitivity psychosis is discussed.

Özet

Tardiv diskinezi sıklıkla yıllar boyu antipsikotik ilaç kullanımından sonra ortaya çıkmaktadır ve yaşam boyu tedavi dozu ile ilişkili görünmektedir. Tardiv diskinezinin bir alt tipi olarak kabul edilen çekilme diskinezisi tablosunda diskinezi belirtileri ilaç dozunun hızlı azaltılması veya ani kesilmesinden kısa bir süre sonra ortaya çıkar. Sıklıkla tardiv diskineziyle birlikte görülen ve oluşumunda tardiv diskineziyle benzer mekanizmaların rol oynadığı öne sürülen bir durum olan süpersensitivite psikozu, kullanılan antipsikotiğin hızlı azaltılması veya ani kesilmesine bağlı olarak oluşan psikotik relaps durumudur. Genel olarak atipik antipsikotikler tipik olanlarla kıyaslandığında tardiv diskineziye daha az yatkınlık oluş- turma ile ilişkilendirilir. Bunun da ötesinde klozapinin ve olanzapinin tardiv diskinezi bulgularında düzelme veya tamamen iyileşme sağlama potansiyeli olduğu bildirilmiştir. Bu yazıda olanzapin tedavisinin kesilmesine bağlı olarak çekilme diskinezisi ve supersensitivite psikozu olgusu tartışılmıştır.

🔖

Cite This Article

KARAŞ, H., GÜDÜK, M., SAATÇİOĞLU, Ö. (2016). Withdrawal-Emergent Dyskinesia and Supersensitivity Psychosis Due to Olanzapine Use. Nöropsikiyatri Arşivi, Cilt: 53 - Sayı: 2, 178–180. https://ajindex.com/articles/292846

References (2)

  1. American Psychiatric Association. Tardive dyskinesia: a task force report of the American Psychiatric Association. Washington DC: American Psychiatric Association, 1992
  2. Chouinard G. Severe cases of neuroleptic-induced supersensitivity psychosis. Diagnostic criteria for the disorder and its treatment. Schizophr Res 1991; 5:21-33. [CrossRef] 3. Chouinard G, Chouinard VA. Atypical antipsychotics: CATIE study, drug-ınduced movement disorder and resulting iatrogenic psychiatric-like symptoms, supersensitivity rebound psychosis and withdrawal discontinuation syndromes. Psychother Psychosom 2008; 77:69-77. [CrossRef] 4. Sachdev PS. The current status of tardive dyskinesia. Aust N Zeal J Psychiatry 2000; 34:355-369. [CrossRef] 5. Fallon, P, Dursun, S. A naturalistic controlled study of relapsing schizophrenic patients with tardive dyskinesia and supersensitivity psychosis. J Psychopharmacol 2011; 25:755-762. [CrossRef] 6. Correll CU, Leucht S, Kane JM. Lower risk for tardive dyskinesia associated with secondgeneration antipsychotics: A systematic review of 1-year studies. Am J Psychiatry 2004; 161:414-425. [CrossRef] 7. Kimberly HL, Johnson CG, Littrell S, Peabody CD. Marked reduction of tardive dyskinesia with olanzapine. Arch Gen Psychiatry 1998; 55:279-280. [CrossRef] 8. Schooler NR, Kane JM. Research diagnoses for tardive dyskinesia. Arch Gen Psychiatry 1982; 39:486-487. [CrossRef] 9. Dunayevich E, Strakowski SM. Olanzapine-induced tardive dystonia. Am J Psychiatry 1999; 156:1662. [CrossRef]