Journals / Nöropsikiyatri Arşivi / 2010 / Cilt: 47 - Sayı: 2

Parkinson hastalığı geliştiren esansiyel tremor ile esansiyel tremor arasındaki farklılıklar

Differences between essential tremor developing parkinson’s disease and essential tremor

Pages
101–104
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusions: Our results point out that some patients with ET, having asymmetrical tremor, late onset and REM-SBD history may develop PD.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Essential tremor (ET) is the most prevalent extrapyramidal disorder and some ET patients may later develop Parkinson’s disease (PD).
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Key Findings & Data:Methods: One hundred forty-four patients with ET and 336 PD patients were retrospectively assessed from their clinical charts, and their current age, gender, onset age of ET, family history of ET, asymmetrical or symmetrical tremor and history of REM-Sleep Behavior Disorders (REM-SBD) were recorded.
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Conclusion & Impact:Conclusions: Our results point out that some patients with ET, having asymmetrical tremor, late onset and REM-SBD history may develop PD.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Essential tremor (ET) is the most prevalent extrapyramidal disorder and some ET patients may later develop Parkinson’s disease (PD). However, up to date, precise association was not determined. To understand the relationship between ET and PD, we investigated differences between patients with ET and ET developing PD (ETPD) in terms of demographic and clinical characteristics. Methods: One hundred forty-four patients with ET and 336 PD patients were retrospectively assessed from their clinical charts, and their current age, gender, onset age of ET, family history of ET, asymmetrical or symmetrical tremor and history of REM-Sleep Behavior Disorders (REM-SBD) were recorded. Results: Thirty-three patients who had ET prior to PD were evaluated as ETPD patients based on previous clinical records. The mean duration from ET to PD was 12±11.4 years (range: 1-47). There was no difference in gender between the groups. The mean age, the mean age at ET onset, asymmetrical tremor and REM-SBD history were significantly lower in ET patients compared to ETPD patients. The family history of ET and head tremor was more frequent in ET patients than in ETPD. Conclusions: Our results point out that some patients with ET, having asymmetrical tremor, late onset and REM-SBD history may develop PD.

Özet

Amaç: Esansiel tremor (ET) en yaygın ekstrapiramidal hastalıktır ve bazı ET hastaları sonradan Parkinson Hastalığı (PH) geliştirebilirler. Ancak bugüne kadar kesin bir birliktelik tanımlanmamıştır. Biz ET ve PH arasındaki ilişkiyi anlamak için, ET ile ET sonrası PH geliştiren hastalar arasındaki farklılıkları demografik ve klinik açıdan araştırdık. Yöntemler: Yüz kırk dört ET ve 336 PH hastası retrospektif olarak klinik kayıtlarından değerlendirildi ve yaş, cinsiyet, ET başlama yaşı, ailede ET öyküsü, asimetrik veya simetrik tremor REM-uyku davranış bozukluğu (REM-SBD) öyküsü kaydedildi. Bulgular: Otuz üç PH öncesi ET’si olan hasta önceki klinik kayıtlarına dayanarak ETPD hastası olarak değerlendirildi. ET’den PH’e dönme süresi ortalama 12±11.4 yıl idi (1-47). Gruplar arasında cinsiyet farklılığı yoktu. ET hastalarında ETPD hastaları ile karşılaştırıldığında ortalama yaş, ET başlama yaşı, asimetrik tremor ve REM-SBD öyküsü anlamlı olarak daha azdı. ET hastalarında ailede ET öyküsü ve baş tremoru ETPD’den daha fazla idi. Sonuç: Bizim sonuçlarımız asimetrik tremor, geç başlangıçlı ET ve REM-SBD öyküsü olan ET hastalarının sonradan PH geliştirebileceğine dikkati çekmiştir.

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Cite This Article

YILDIZ, B. G., ÇOBAN, A., HANAĞASI, H. A., GÜRVİT, İ. H., YAZICI, J. (2010). Parkinson hastalığı geliştiren esansiyel tremor ile esansiyel tremor arasındaki farklılıklar. Nöropsikiyatri Arşivi, Cilt: 47 - Sayı: 2, 101–104. https://ajindex.com/articles/292724

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