Journals / Nöropsikiyatri Arşivi / 2015 / Cilt: 52 - Sayı: 1

Neuropathy and Dysautonomia in Patients with Obstructive Sleep Apnea Syndrome

Obstruktif Uyku Apne Sendromunda Nöropati ve Disotonomi

Pages
24–28
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: OSAS indicates a risk of possible peripheral neuropathy and autonomic dysfunction risk increases in positive correlation with level of OSAS

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: The aim of our study is to search for the existence of neuropathy, dysautonomia and to identify the correlations of sickness level of patients with Obstructive Sleep Apnea Syndrome (OSAS).Methods: The research is based on the real cases at Dokuz Eylul University of Medicine Sleep and Epilepsy Center, observed during September 2008May 2009.
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Key Findings & Data:The patients were selected by polysomnography samples based on 20 persons at same ages with following criteria; high leveled OSAS (AHİ>=30), low OSAS (5<=AHİ<30) and healthy participants.
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Conclusion & Impact:Conclusion: OSAS indicates a risk of possible peripheral neuropathy and autonomic dysfunction risk increases in positive correlation with level of OSAS
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Introduction: The aim of our study is to search for the existence of neuropathy, dysautonomia and to identify the correlations of sickness level of patients with Obstructive Sleep Apnea Syndrome (OSAS).Methods: The research is based on the real cases at Dokuz Eylul University of Medicine Sleep and Epilepsy Center, observed during September 2008May 2009. The patients were selected by polysomnography samples based on 20 persons at same ages with following criteria; high leveled OSAS (AHİ>=30), low OSAS (5<=AHİ<30) and healthy participants. Classical ENMG protocol, symphatic skin response and R-R interval variation test were performed on these samples esults: High and low leveled OSAS patients had a statistically significant (p<0.05) decrease in the average velocity of motor conduction in right tibialis posterior when compared to the control group. Besides we observed an statistically significant (p<0.05) increase in the average amplitud of symphatic skin responses in high leveled OSAS patients than control group. Conclusion: OSAS indicates a risk of possible peripheral neuropathy and autonomic dysfunction risk increases in positive correlation with level of OSAS

Özet

Amaç: Bu çalışmanın amacı obstruktif uyku apne sendromu (OUAS) hastalarında nöropati ve otonomik disfonksiyon varlığının araştırılması, bunların hastalık şiddeti ile ilişkisinin belirlenmesidir. Yöntem: Çalışmaya Dokuz Eylül Üniversitesi Tıp Fakültesi Uyku ve Epilepsi Merkezi'ne Eylül 2008 ve Mayıs 2009 tarihleri arasında başvuran polisom-nografisi çekilerek ağır OUAS (AHİ>=30) tanısı almış 20 hasta, hafif OUAS (5<=AHİ<30) tanısı almış 20 hasta ve aynı yaş grubundaki 20 sağlıklı olgu alınmıştır. Olgulara klasik elektronöromiyografi (ENMG) polinöropati pro-tokolü, sempatik deri yanıtı, R-R aralık değişkenliği testleri yapılmıştır.Bulgular: Ağır ve hafif OUAS gruplarında tibialis posterior sinir iletim hız-larının kontrol grubuna göre istatistiksel olarak anlamlı azaldığı saptanmıştır (p<0,05). Ağır OUAS grubu sempatik deri yanıtı amplitüdlerinde kontrol grubuna göre istatistiksel olarak anlamlı artış gözlenmiştir (p<0,05).Sonuç: OUAS'da hastalığın şiddeti ile korele olarak otonomik disfonksiyon görülme riskinin artabileceği ve OUAS'ın periferal nöropati oluşumunda risk faktörü olabileceği gözlenmiştir.

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Cite This Article

EVLİCE, A. T., UGUREL, B., BAKLAN, B., ÖZTURA, İ. (2015). Neuropathy and Dysautonomia in Patients with Obstructive Sleep Apnea Syndrome. Nöropsikiyatri Arşivi, Cilt: 52 - Sayı: 1, 24–28. https://ajindex.com/articles/292429

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