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Journals / Neurological sciences and neurophysiology (Online) / 2018 / Cilt: 35 - Sayı: 3

Impaired autonomic and repolarization abnormalities in patients with facioscapulohumeral dystrophy

Çağlar Emre ÇAĞLIYAN
Hakan GELİNCİK
Aziz İnan ÇELİK
Filiz KOÇ
Pages
127–131
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: These findings suggest that autonomic and repolarization abnormalities might be observed in patients with FSHD in spite of normal structural and functional myocardial function.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Facioscapulohumeral Dystrophy (FSHD) is one of the most common adult muscular dystrophies.
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Key Findings & Data:We aim to investigate structural, functional and arrhythmic abnormalities in patients with FSHD Type-1.
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Conclusion & Impact:Conclusion: These findings suggest that autonomic and repolarization abnormalities might be observed in patients with FSHD in spite of normal structural and functional myocardial function.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objective: Facioscapulohumeral Dystrophy (FSHD) is one of the most common adult muscular dystrophies. We aim to investigate structural, functional and arrhythmic abnormalities in patients with FSHD Type-1. Methods: Left ventricular mass, left ventricular tissue doppler analysis and myocardial performance index (MPI) were calculated in Type-1 FSHD and healthy controls. A 24-hour ambulatory electrocardiogram (ECG) analysis was performed. T wave peak to end (Tp-e) interval and Tp-e/QT ratio was calculated. Results: In the study average heart rate was significantly higher (93.6±10.1 min-1 vs 74.3±5.6 min-1; p=0.0001) and standard deviation of N-N intervals was significantly lower (47.43±15.49 vs 69.85±19.18; p=0.001) in FSHD Group. Tp-e interval was longer (78.6±14.6 msec vs 64.3±16.5 msec; p=0.031) and Tp-e/QT ratio was larger (22.9±3.2 vs 17.8±5.4; p=0.018) in the FHSD Group. Conclusion: These findings suggest that autonomic and repolarization abnormalities might be observed in patients with FSHD in spite of normal structural and functional myocardial function.

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Cite This Article

ÇAĞLIYAN, Ç. E., GELİNCİK, H., ÇELİK, A. İ., KOÇ, F. (2018). Impaired autonomic and repolarization abnormalities in patients with facioscapulohumeral dystrophy. Neurological sciences and neurophysiology (Online), Cilt: 35 - Sayı: 3, 127–131. https://ajindex.com/articles/290607

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References (2)

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