Journals / MN Kardiyoloji / 2019 / Cilt: 26 - Sayı: 4

P-Wave Dispersion in Patients with Depressive Disorder

Depresif Bozukluğu Olan Hastalarda P Dispersiyonu

Pages
235–239
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: In conclusion, it was found that P-dispersion, which indicates an increased atrial arrhythmia and cardiovascular mortality risk, was high in depressive patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Increased sympathetic activity in patients with depression may be a risk factor for arrhythmia.
📊
Key Findings & Data:Material and Method: Thirty patients with depressive disorder and 30 healthy controls with similar sociodemographic characteristics were included in our case control study.
💡
Conclusion & Impact:Conclusion: In conclusion, it was found that P-dispersion, which indicates an increased atrial arrhythmia and cardiovascular mortality risk, was high in depressive patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Increased sympathetic activity in patients with depression may be a risk factor for arrhythmia. It was reported that P-wave dispersion is a sensitive and specific precursor of atrial fibrillation in various clinical cases and can be used as an indicator for paroxysmal atrial fibrillation. In the present study, we aimed to investigate whether P-dispersion differed between patients diagnosed with depression and the control group and whether this was correlated with depression scores. Material and Method: Thirty patients with depressive disorder and 30 healthy controls with similar sociodemographic characteristics were included in our case control study. All participants completed a sociodemographic data form and the Beck Depression Inventory was applied to all participants. P-dispersion was calculated using twelve-lead ECGs. Results: The Beck Depression Scale scores of the patient group (33.53±11.4) were significantly higher when compared to the control group (2.73±3.17) (p <0.001). P-dispersion values (milliseconds) were significantly higher in the patient group when compared to the control group (43.67±12.73 vs 29.67±10.33) (p <0.001). It was determined that there was a positive correlation between P-dispersion values and Beck Depression Inventory scores (r =0.445, p =0.000). Conclusion: In conclusion, it was found that P-dispersion, which indicates an increased atrial arrhythmia and cardiovascular mortality risk, was high in depressive patients. Also, P-dispersion values increased in direct proportion to the depression scores.

Özet

Amaç: Depresyon hastalarında artan sempatik aktivite aritmiler için bir risk faktörü oluşturabilmektedir. P dalga dispersiyonunun, çeşitli klinik durumlarda atriyal fibrilasyonun sensitif ve spesifik bir habercisi olduğu ve paroksismal atriyal fibrilasyon için bir gösterge olarak kullanılabileceği bildirilmiştir. Çalışmamızda depresyon tanısı almış hastalarda P-dispersiyonunun kontrol grubuna göre farklılık gösterip göstermediğini ve bunun depresyon puanları ile ilişkili olup olmadığını araştırmayı amaçladık. Gereç ve Yöntem: Vaka kontrol çalışmamıza, depresif bozukluk tanısı konan 30 hasta ve hasta grubuyla benzer sosyodemografik özelliklere sahip olan 30 sağlıklı kontrol grubu alındı. Tüm katılımcılara sosyodemografik veri formu doldurulup, Beck Depresyon Ölçeği uygulandı. Tüm katılımcıların on iki derivasyonlu EKG’leri çekilerek, P - dispersiyonu hesaplandı. Bulgular: Hasta grubunun Beck Depresyon Ölçekleri (33,53±11,4) kontrol grubundan (2,73±3,17) anlamlı olarak daha yüksek bulundu (p<0,001). P-dispersiyonu değerleri (milisaniye), hasta grubunda, kontrol grubuna göre (43,67±12,73 vs 29,67±10,33) istatistiksel olarak anlamlı düzeyde yüksek bulundu (p<0,001). P-dispersiyonu değerleri ile Beck Depresyon Ölçeği puanları arasında pozitif bir korelasyon belirlendi (r= 0,445, p =0,000). Sonuç: Çalışmamızda, atriyal aritmi ve kardiyovasküler mortalite için artmış riski işaret eden P-disp, depresyonlu hastalarda yüksek olarak saptandı. Yine P-dispersiyonu değerleri depresyon puanları ile doğru orantılı olarak artmakta idi.

🔖

Cite This Article

KORKMAZ, H., KORKMAZ, S., AKSOY, D. B., ÇAKAR, M. (2019). P-Wave Dispersion in Patients with Depressive Disorder. MN Kardiyoloji, Cilt: 26 - Sayı: 4, 235–239. https://ajindex.com/articles/287659

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Ferketich AK, Schwartzbaum JA, Frid DJ, Moeschberger ML. Depression as an antecedent to heart disease among women and men in the NHANES I study. Arch Intern Med. 2000;160:1261-8
  2. Whooley MA, de Jonge P, Vittinghoff E, et al. Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease. JAMA. 2008;300:2379-88
  3. Frasure-Smith N, Lesperance F, Talajic M. Depression following myocardial infarction. Impact on 6-month survival. JAMA. 1993;270:1819-25
  4. Remme WJ. The sympathetic nervous system and ischaemic heart disease. Eur Heart J. 1998;19:62-71
  5. Podrid PJ, Kowey PR. Cardiac Arrhythmia, Mechanisms, Diagnosis&Management. 2nd ed; Lippincott Williams& Wilkins, Philadelphia. 2001, p:111-651
  6. Uyarel H, Okmen E, Cobanoglu N, Karabulut A, Cam N. Effects of anxiety on QT dispersion in healthy young men. Acta Cardiol. 2006;61:83-7
  7. Yavuzkir M, Atmaca M, Dagli N, et al. P-wave dispersion in panic disorder. Psychosom Med. 2007;69(4):344-7
  8. Tosu AR, Demir S, Kaya Y, et al. Increased QT dispersion and P wave dispersion in major depressive disorder. Exp Clin Cardiol. 2013;18(2):110-2
  9. Beck AT. An inventory for measuring depression. Arch Gen Psychiatry. 1961;4:561-71
  10. Rosmond R. Role of stress in the pathogenesis of the metabolic syndrome. Psychoneuroendocrinology. 2005;30:1-10
  11. Grippo AJ, Johnson AK. Biological mechanisms in the relationship between depression and heart disease. Neurosci Biobehav Rev. 2002;26:941-62 12. Uyarel H, Uzunlar B, Unal Dayi S, Tartan Z, Samur H, Kasikcioglu H. Anxiety and P wave dispersion in a healthy young population. Cardiology. 2005;104:162-8
  12. Erdem M, Sarıçam E, Çelik C, Isılak Z, Aparcı A, Uz O. Sağlıklı genç erkeklerde sürekli öfke düzeyi ve öfke tarzının P dalga değişkenliği üzerine etkisi. Hipokrat Kardiyoloji. 2008;42: 65-9
  13. Yeragani VK, Pohl R, Jampala VC, et al. Increased QT variability in patients with panic disorder and depression. Psychiatry Res. 2000;93:225-35
  14. Oksuz F, Yarlioglues M, Ozturk S, et al. Atrial electromechanical delay analysed by tissue Doppler echocardiography is prolonged in patients with generalised anxiety disorders. Kardiol Pol. 2017;75(6):581-8
  15. Köse S, Aytemir K, Sade E, et al. Detection of patients with hypertrophic cardiomyopathy at risk for paroxysmal atrial fibrillation during sinus rhythm by P-wave dispersion. Clin Cardiol 2003;26:431-4
  16. Perzanowski C, Ho AT, Jacobson AK. Increased P-wave dispersion pre