Journals / Osteoporoz Dünyasından / 2005 / Cilt: 11 - Sayı: 2

Relation between smoking and bone mineral density

Sigara kullanımı ve kemik mineral yoğunluğu ilişkisi

Pages
68–74
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was concluded that with this study group, nicotine intake did not alter the BMD values measured at the region of L2-L4 vertebrae in both genders.

📌 3 Key Takeaways

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Objective & Hypothesis:Studies examining the relation between the nicotine intake through cigarette smoking and Bone Mineral Density (BMD) are limited and contradictory.
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Key Findings & Data:Relation between BMD of L2-L4 vertebrae and total femur was measured with dual-photon X-ray absorptiometry (DXA) and data of nicotine intake of the 708 female and 307 male, total 1015 individuals who performed the “identification form concerning the risk factors for hip fractures, such as dietary factors and physical activity, between cases and population controls, in several countries” from the World Health Organization (WHO) was investigated.
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Conclusion & Impact:It was concluded that with this study group, nicotine intake did not alter the BMD values measured at the region of L2-L4 vertebrae in both genders.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Lumbar omurga · Sigara içme · Kemik yoğunluğu

Abstract

Studies examining the relation between the nicotine intake through cigarette smoking and Bone Mineral Density (BMD) are limited and contradictory. The aim of this study was to investigate the relation between nicotine intake through smoking and BMD. Relation between BMD of L2-L4 vertebrae and total femur was measured with dual-photon X-ray absorptiometry (DXA) and data of nicotine intake of the 708 female and 307 male, total 1015 individuals who performed the “identification form concerning the risk factors for hip fractures, such as dietary factors and physical activity, between cases and population controls, in several countries” from the World Health Organization (WHO) was investigated. It was concluded that with this study group, nicotine intake did not alter the BMD values measured at the region of L2-L4 vertebrae in both genders. In men, however, nicotine intake altered the total femur BMD values significantly. Nicotine intake is significantly higher in osteoporotic males when total proximal BMD values are considered.

Özet

Sigara içimiyle alınan nikotin miktarı ve kemik mineral yoğunluğu (KMY) arasındaki ilişkiyi inceleyen sınırlı sayıda kapsamlı çalışma bulunmaktadır. Ayrıca nikotin ve KMY arasındaki ilişkiyi inceleyen çalışmaların sonuçları farklılık göstermektedir. Bu amaçla sigara içimiyle alınan nikotin miktarı ve KMY arasındaki ilişkinin incelenmesi amaçlanmıştır. Çalışma kapsamında lomber omurga L2-L4 ve femur üst uç toplamında çift enerjili X-ışını absorbsiyometresiyle (DXA) ölçülen KMY ve eş zamanlı olarak Dünya Sağlık Örgütünün (WHO) “Farklı ülkelerdeki olgular ve toplumlar arasında kalça kırığı risk faktörlerini örneğin diyet ve fiziksel etkinlik bağlamında inceleme formunu” dolduran 708 kadın, 307 erkek, toplam 1015 bireyin sigara içimiyle aldıkları nikotin miktarı verileri arasındaki ilişki incelenmiştir. Alınan nikotin miktarının her iki cinste de L2-L4 omurga KMY’nu istatistiksel olarak etkilemediği belirlenmiştir. Buna karşın erkeklerin femur üst uç bölgesinde KMY’nun alınan nikotinden anlamlı olarak etkilendiği sonucuna varılmıştır. Sonuç olarak osteoporozun değiştirilebilir belirleyicilerinden birisi olan sigara içimiyle alınan nikotin miktarı ile KMY arasındaki ilişki incelendiğinde cinse ve ölçümün yapıldığı bölgeye bağlı farklılıkların olduğu saptanmıştır. Örneklem özelinde nikotin tüketim miktarının toplam femur üst uç osteoporotik erkeklerde istatistiksel olarak anlamlı yüksek olduğu belirlenmiştir.

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Cite This Article

BAŞARAN, M. A., SARIBAY, G. F., AKIN, S., KORKUSUZ, F. (2005). Relation between smoking and bone mineral density. Osteoporoz Dünyasından, Cilt: 11 - Sayı: 2, 68–74. https://ajindex.com/articles/286846

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References (16)

  1. Lin JT, Lane JM. Osteoporosis. A Review. Clin Orthop Rel Res 2004;425:126-134
  2. Lee LL, Lee JSC, Waldman SD, et al. Polycylic aroma- tic hydrocarbons present in cigarette smoke cause bo- ne loss in an ovariectomized rat model. Bone. 2002;30:917-923
  3. Ward KD, Klesges RC. A meta-analysis of the effects of cigarette smoking on bone mineral density. Calcifi- ed Tissue Int. 2001;68: 259-270
  4. Hildebolt CE, Pilgram TK, Yokoyama-Crothers N, et al. Alveolar bone height and postcranial bone mineral density: Neagtive effects of cigarette-smoking and parity. J Periodontol. 2000;71:683-689
  5. Payne JB, Reinhardt RA, Nummikoski PV, et al. The association of cigarette smoking with alveolar bone loss in postmenopausal females. J Clin Periodontol. 2000:27: 658-664
  6. Hermann AP, Brot C, Gram J, et al. Premenopausal smoking and bone density in 2015 perimenopausal women. J Bone Miner Res. 2000; 15: 780-787
  7. Bjarnason NH, Christiansen C. The influence of thin¬ness and smoking on bone loss and response to hormone replacement therapy in early postmenopausal women. J Clin Endocr Metab. 2000;85: 590-596
  8. Fung YK, Iwaniecz U, Cullen DM, et al. Long-term effects of nicotine on bone and calciotropic hormones in adult female rats. Pharmacol Toxicol. 1999;85: 181-187
  9. Vogel JM, Davis JW, Nomura A, et al. The effects of smoking on bone mass and the rates of bone loss among elderly Japanese-American men. J Bone Miner Res. 1997;12: 1495-1501
  10. Broulik PD, Jarab J. The Effect of Chronic Nicotine Administration on Bone-Mineral Content in Mice. Horm Metab Res. 1993;25: 219-221
  11. Krall EA, Dawsonhughes B. Smoking and Bone Loss Among Postmenopausal Women. J Bone Miner Res. 1991;6:331-338
  12. Rapuri PB, Gallagher JC, Balhorn KE, et al. Alcohol intake and bone metabolism in elderly women. Am J Clin Nutr. 2000;72: 1206-1213
  13. Gerdhem P, Obrant KJ. Effects of cigarette-smoking on bone mass as assessed by dual-energy X-ray ab- sorptiometry and ultrasound. Osteoporosis Int. 2002;13: 932-936
  14. Franceschi S, Schinella D, Bidoli E, et w. The influen- ce of body size, smoking, and diet on bone density in pre and postmenopausal women. Epidemiology. 1996;7:411-414
  15. Silvennoinen JA, Lehtola JK, Niemela SE. Smoking is a risk factor for osteoporosis in women with inflamma- tory bowel disease. Scandinavian J Gastroenterol. 1996;31: 367-371
  16. Albrand G, Munoz F, Sornay-Rendu E, etal. Indepen- dent predictors of all osteoporosis-related fractures in healthy postmenop