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Journals / Osteoporoz Dünyasından / 2002 / Cilt: 8 - Sayı: 3

Risk factors in osteoporotic vertebra fractures

Osteoporotik vertebra fraktürlerinde risk faktörleri

Rezzan GÜNAYDIN
Neşe ÖLMEZ
Taciser KAYA
Dirim Berna VİDİNLİ
Asuman MEMİŞ
Pages
105–109
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Of the 5 risk factors chosen (age, L.2-L4 BMD, L.2-L.4 T score, body weight <57 kg, milk consumption before age 50) only patient's age was found to be statistically important in estimating vertebral fracture risk (p=0.032).There was statistically significant positive correlation between vertebral deformity score (evaluated according to Kleerekoper method) and patient's age and postmenopausal years (respectively p=0.001, p=0.006).

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to investigate the risk factors for osteoporotic vertebral fractures in postmenopausal women. 44 postmenopausal women whose L 2-L4 T scores were < -2.5 SD with a mean age of 66.38+ 6.47 years were included in this study.
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Key Findings & Data:Age, postmenopausal years, body mass index, milk consumption (before and after age 50), family history of osteoporosis and osteoporotic fracture, patient's previous fracture history, tobacco use, number of pregnancies, surgical menopause were questioned in all patients.
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Conclusion & Impact:Of the 5 risk factors chosen (age, L.2-L4 BMD, L.2-L.4 T score, body weight <57 kg, milk consumption before age 50) only patient's age was found to be statistically important in estimating vertebral fracture risk (p=0.032).There was statistically significant positive correlation between vertebral deformity score (evaluated according to Kleerekoper method) and patient's age and postmenopausal years (respectively p=0.001, p=0.006).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Aile özellikleri · Osteoporoz · Omurga

Abstract

The aim of this study was to investigate the risk factors for osteoporotic vertebral fractures in postmenopausal women. 44 postmenopausal women whose L 2-L4 T scores were < -2.5 SD with a mean age of 66.38+ 6.47 years were included in this study. Age, postmenopausal years, body mass index, milk consumption (before and after age 50), family history of osteoporosis and osteoporotic fracture, patient's previous fracture history, tobacco use, number of pregnancies, surgical menopause were questioned in all patients. DEXA was used to evaluate bone mineral density . Kleerekoper method was used to evaluate the fractures between T4 and L5 vertebra on lateral thoracal and lumbar X rays. When 25 patient with vertebral fractures compared with 19 patients without fracture ,only patient's age showed statistically significant difference between groups ( p=0.035). Of the 5 risk factors chosen (age, L.2-L4 BMD, L.2-L.4 T score, body weight <57 kg, milk consumption before age 50) only patient's age was found to be statistically important in estimating vertebral fracture risk (p=0.032).There was statistically significant positive correlation between vertebral deformity score (evaluated according to Kleerekoper method) and patient's age and postmenopausal years (respectively p=0.001, p=0.006).

Özet

Bu çalışma osteoporoz için tanımlanmış çeşitli risk faktörlerinin postmenopozal kadınlarda radyolojik vertebra fraktürü oluşumundaki etkisini değerlendirmek amacı ile yapıldı. L2-L.4 vertebra T skoru < -2.5 SD olan 44 olgu (yaş ört: 66.38+ 6.47 yıl) çalışmaya alındı. Olgularda yaş, postmenopozal süre, vücut kitle indeksi, süt tüketimi ( 50 yaş altı ve üstü), ailede osteoporoz ve osteoporotik kırık öyküsü, hastada vertebra dışı osteoporotik kırık, sigara kullanımı, gebelik sayısı sorgulandı. Kemik mineral yoğunluğu ölçümleri (KMY) DEXA ile değerlendirildi. Olguların lateral torakal ve lomber vertebra grafileri çektirildi. T4-L5 arası vertebral fraktürler Kleerekoper yöntemi ile değerlendirildi. Fraktürlü 25 ve fraktürsüz 19 olgu risk faktörleri açısından karşılaştırıldığında sadece hasta yaşı istatistiksel olarak anlamlı fark göstermekteydi (p= 0.035). Logistic regresyon analizi ile incelendiğinde seçilen 5 risk faktöründen (yaş, L2-L4 KMY, L2-L4 T skoru, kilo <57 kg, 50 yaş öncesi süt tüketimi) sadece ileri hasta yaşının vertebral fraktür riskini kestirmede istatistiksel olarak anlamlı rolü olduğu saptandı (p= 0.032). Kleerekoper yöntemi ile hesaplanan vertebra deformite skoru ile risk faktörlerinin korelasyonu istatistiksel olarak incelendiğinde hasta yaşı ve postmenopozal sürenin vertebra deformite skoru ile pozitif korelasyon gösterdiği saptandı ( sırasıyla p=0.001, p=0.006).

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Cite This Article

GÜNAYDIN, R., ÖLMEZ, N., KAYA, T., VİDİNLİ, D. B., MEMİŞ, A. (2002). Risk factors in osteoporotic vertebra fractures. Osteoporoz Dünyasından, Cilt: 8 - Sayı: 3, 105–109. https://ajindex.com/articles/286877

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