Journals / Osteoporoz Dünyasından / 2007 / Cilt: 13 - Sayı: 1

Bone mineral density in men

Erkeklerde kemik mineral yoğunluğu

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Routine analysis of blood biochemistry and DXA should be performed in adult men. (From the World of Osteoporosis 2007;13:1-5)

📌 3 Key Takeaways

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Objective & Hypothesis:Aims: This study is designed to evaluate bone mineral density (BMD) in men who attend to Physical Medicine and Rehabilitation outpatient clinic.
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Key Findings & Data:Patients and Medhods: 42 men were included into the study.
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Conclusion & Impact:Routine analysis of blood biochemistry and DXA should be performed in adult men. (From the World of Osteoporosis 2007;13:1-5)
🔬Design:Research Article
📍Scope:2007 Verileri
⚙️Variables:Osteokalsin · Kemik yoğunluğu · Absorptiyometri

Abstract

Aims: This study is designed to evaluate bone mineral density (BMD) in men who attend to Physical Medicine and Rehabilitation outpatient clinic. Patients and Medhods: 42 men were included into the study. They were evaluated in 3 groups according to their age (30-75); age between 30-45, 45-60 and over 60 yrs. BMD of lumbar spine (L2-L4) and femur neck were evaluated by using dual x-ray absorptiometry (DXA). Serum paratiroid hormone, osteocalcin, 25 (OH) D3 vitamine levels and urinary deoxypridinoline levels were evaluated. Results: Mean age of the patients were 51.24±12.23 yrs in femur neck and in lumbar region, 70% and 15% of the patients between 60-75 yrs, 53% and 7% of the patients between 45-60 yrs and 23% and 8% of the patients between 30-45 yrs have osteoporosis, respectively. Between the groups femur neck BMD and L2-L4 BMD were significantly different (p=0.043 and p=0.008, respectively). Serum PTH levels were high and serum 25(OH)D3 levels were low in all groups. There were no significant difference between the groups regarding bone turnover markers. Seven patients had osteoporotic fractures (6 vertebral, 1 hip). Correlation was found between fractures and L2-L4 BMD ( r=-0.322, p=0.043). Conclusion: Osteoporosis is common also in men, particularly in the middle and old ages. Routine analysis of blood biochemistry and DXA should be performed in adult men. (From the World of Osteoporosis 2007;13:1-5)

Özet

Amaç: Bu çalışma Fiziksel Tıp ve Rehabilitasyon polikliniğine başvuran erkek hastalarda kemik mineral yoğunluğunu (KMY) değerlendirmek amacıyla düzenlenmiştir. Hastalar ve Yöntem: 42 erkek hasta çalışmaya dahil edildi. Hastalar yaşlarına göre (30-75 yaş) 30-45, 45-60 ve 60 yaş üstü olmak üzere 3 gruba ayrıldı. Lomber omurga (L2-L4) ve femur boynu KMY değerleri dual energy x ray absorpsiyometri (DXA) ile değerlendirildi. Serum parathormon, osteokalsin, 25(OH)D3 ve 24 saatlik idrar deoksipridinolin düzeyleri ölçüldü. Bulgular: Hastaların yaş ortalaması 51,24±12,23 yıldı. Femur boynunda ve lomber bölgede sırasıyla hastaların 60-75 yaş grubunda %70 ve %15, 45-60 yaş grubunda %53 ve % 7 ve 30-45 yaş grubunda %23 ve %8 osteoporoz vardı. Gruplar arasında lomber omurga ve femur boynu KMY değerleri anlamlı olarak farklı bulundu (sırasıyla p=0,043 ve p=0,008). Her üç grupta da serum PTH seviyeleri yüksek, serum 25(OH)D3 seviyeleri düşüktü. Kemik döngüsü belirleyicileri açısından fark saptanmadı. Yedi hastada osteoporotik kırık vardı (6 vertebral, 1 kalça). Kırık ile L2-L4 KMY arasında korelasyon saptandı ( r=-0,322, p=0,043). Sonuçlar: Osteoporoza özellikle orta yaş ve yaşlı erkeklerde de sık rastlanmaktadır. Her yetişkin erkekte rutin kan biyokimyası ve DXA ile KMY ölçümleri yapılması önerilmektedir. (Osteoporoz Dünyasından 2007;13:1-5)

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Cite This Article

KÜLCÜ, D. G., YANIK, B., YALÇIN, P. (2007). Bone mineral density in men. Osteoporoz Dünyasından, Cilt: 13 - Sayı: 1, 1–5. https://ajindex.com/articles/286360

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References (20)

  1. Gökçe Kutsal Y. Osteoporoz. Beyazova M, Gökçe-Kutsal Y (Eds). Fiziksel Tıp ve Rehabilitasyon, Cilt 2. Ankara Güneş Kitabevi Ltd Şti, 2000: 1872-93
  2. Eastell R, Boyle IT, et al. Management of male osteoporosis: report of the UK Consensus Group. QJM 1998; 91: 71-92
  3. Pernow Y, Granberg B,et al. Osteoblast dysfunction in male idiopathic osteoporosis. Calcif Tissue Int 2006; 78: 90-7
  4. Esenyel M, Özaras N,et al. Erkeklerde Osteoporoz. Osteoporoz Dünyasından 2004; 10: 11-5
  5. Campion JM, Maricic MJ. Osteoporosis in men. Am Fam Physician 2003; 67: 1521-6
  6. Tüzün, Akırmak Ü, Dinç A. Osteoporozun tanımı ve sınıflandırılması. Kemik ve eklem dekadında osteoporoz. Aventis Pharma Türkiye, İstanbul 2002: 9-13
  7. Lems WF, Jahangier ZN, Raymakers A et al. Methods to score vertebral deformities in patients with rheumatoid arthritis. Br J Rheum 1997: 36: 220-4
  8. Orwoll ES. Osteoporosis in men. Endocr Rev 1995; 16: 87-116
  9. Riggs BL, Melton LJ, Rob RA, et al. Population based study of age and sex differences in bone volumetric density, s,ze, geometry and structure at different skeletal sites. J Bone Miner Res 2004; 19: 1945-54
  10. Finkelstein JS. Overview of osteoporosis in men. Available at: http://www.uptodate.com/patient_info/topicpages/topics/2092819.asp. Accessed in January 15, 2002
  11. Binkley N. Osteoporosis in men. Arq Bras Endocrinol Metab 2006; 50: 572-83
  12. Seeman E. The dilemma of osteoporosis in men. Am J Med 1995; 98: 76-88
  13. Stepan JJ, Lachman M, Zverina J, et al. Castrated men exhibit bone loss: effect of calcitonin treatment on biochemical indices of bone remodeling. J Clin Endocrinol Metab 1989; 69: 523-7
  14. Shahinian VB, Kuo YF, Freeman JL, et al. Risk of fracture after androgen deprivation for prostate cancer. N Eng J Med 2005; 352: 154-64
  15. Benito M, Vasilic B, Wehrli FW, et al. Deterioration of trabecular architecture in hypogonadal men. J Clin Endocrinol Metab 2003; 88: 1497-502
  16. Kurland ES, Rosen CJ, Cosman F, et al. Insulin-like growth factor-I in men with idiopathic osteoporosis. J Clin Endocrinol Metab 1997; 82: 2799-805
  17. Looker AC, Orwoll ES, Johnston Jr CC, et al. Prevalence of low femoral bone density in older US adults from NHANES III. J Bone Miner Res 1997; 12: 1761–8
  18. Kanis JA, Melton LJ, Christiansen C, et al. The diagnosis of osteoporosis. J Bone Miner Res 1994; 9: 1137–41
  19. Kelepouris N, Harper KD, Gannon F, et al. Severe osteoporosis in men. Ann Intern Med 1995; 123: 452-60
  20. Campston J. Se